glyV:Gene
{{#css:Suppresslinks.css}}<css>h1 .editsection { display:none;} h2 .editsection { display:none;}</css>
| Quickview | Gene | Gene Product(s) | Expression | Evolution | On One Page |
| Nomenclature | Location(s) and DNA Sequence | Sequence Features | Alleles and Phenotypes | Genetic Interactions | Genetic Resources | Accessions | Links | References | Suggestions |
<protect>
Nomenclature
See Help:Gene_nomenclature for help with entering information in the Gene Nomenclature table.
| Standard name |
glyV |
|---|---|
| Mnemonic |
Glycine |
| Synonyms |
ECK4159, b4163, JWR0112, mutA, glnValpha, suA58, suA78, glyValpha, ins[1], ins |
| edit table |
</protect>
Notes
Location(s) and DNA Sequence
<protect>
See Help:Gene_location for help entering information in the Gene Location and DNA sequence table.
| Strain | Map location | Genome coordinates | Genome browsers | Sequence links |
|---|---|---|---|---|
|
MG1655 |
94.63 minutes, 94.63 minutes |
MG1655: 4390383..4390458 |
||
|
NC_012967: 4370515..4370590 |
||||
|
NC_012759: 4329118..4329193 |
||||
|
W3110 |
|
W3110: 4397040..4397115 |
||
|
DH10B: 4490745..4490820 |
||||
| edit table |
</protect>
Notes
Sequence Features
See Help:Gene_sequence_features for help in entering sequence features in EcoliWiki.
| Feature Type | Strain | Genomic Location | Evidence | Reference | Notes |
|---|---|---|---|---|---|
| edit table |
<protect></protect>
Notes
Alleles and Phenotypes
See Help:Gene_alleles for how to enter or edit alleles and phenotypes in EcoliWiki.
| Allele | Nt change(s) | AA change(s) | Phenotype: Type | Phenotype: Description | Reference | Availability | Comments |
|---|---|---|---|---|---|---|---|
|
glyV55 |
|||||||
|
glyV-50 |
|||||||
|
glyV(mutA1) |
C35T |
mutator |
mutator |
Changes the anticodon to read GAU/C aspartate codons. Thought to be a mutator by virtue of rare mistranslation of proteins involved in DNA fidelity. Alters the first of 3 glycine-tRNA genes at the glyV locus. | |||
|
glyV(mutA2) |
C35T |
mutator |
mutator |
Changes the anticodon to read GAU/C aspartate codons. Thought to be a mutator by virtue of rare mistranslation of proteins involved in DNA fidelity. Alters the second of 3 glycine-tRNA genes at the glyV locus. | |||
|
glyV(mutA) |
C35T |
UVM-constitutive phenotype |
Changes the anticodon to read GAU/C aspartate codons. | ||||
| edit table |
<protect></protect>
Notes
Genetic Interactions
<protect>
| Interactor | Interaction | Allele | Score(s) | Reference(s) | Accessions | Notes |
|---|---|---|---|---|---|---|
| edit table |
</protect>
Notes
Genetic Resources
See Help:Gene_resources for help entering information into the Genetic Resources table.
| Resource | Resource Type | Source | Notes/Reference |
|---|---|---|---|
|
Plasmid clone |
Status: Primer 1: Primer 2: | ||
|
Kohara Phage |
|||
|
Linked marker |
est. P1 cotransduction: 26% [8] | ||
|
Linked marker |
est. P1 cotransduction: 23% [8] | ||
| edit table |
<protect></protect>
Notes
Accessions in Other Databases
See Help:Gene_accessions for help with entering information into the Gene Accessions table.
| Database | Accession | Notes |
|---|---|---|
|
Escherichia coli str. K-12 substr. MG1655 | ||
|
Escherichia coli str. K-12 substr. MG1655 | ||
|
Escherichia coli str. K-12 substr. MG1655 | ||
|
Escherichia coli str. K-12 substr. MG1655 | ||
|
Escherichia coli str. K-12 substr. MG1655 | ||
|
Escherichia coli str. K-12 substr. MG1655 | ||
| edit table |
<protect></protect>
Notes
Links
| Name | URL | Comments |
|---|---|---|
| edit table |
<protect>
References
See Help:References for how to manage references in EcoliWiki.
- ↑ Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
- ↑ Chernyaeva, NS et al. (1999) Suppression of nonsense mutations induced by expression of an RNA complementary to a conserved segment of 23S rRNA. J. Bacteriol. 181 5257-62 PubMed
- ↑ 3.0 3.1 Slupska, MM et al. (1996) Mutator tRNAs are encoded by the Escherichia coli mutator genes mutA and mutC: a novel pathway for mutagenesis. Proc. Natl. Acad. Sci. U.S.A. 93 4380-5 PubMed
- ↑ Murphy, HS & Humayun, MZ (1997) Escherichia coli cells expressing a mutant glyV (glycine tRNA) gene have a UVM-constitutive phenotype: implications for mechanisms underlying the mutA or mutC mutator effect. J. Bacteriol. 179 7507-14 PubMed
- ↑ Kitagawa, M et al. (2005) Complete set of ORF clones of Escherichia coli ASKA library (a complete set of E. coli K-12 ORF archive): unique resources for biological research. DNA Res. 12 291-9 PubMed
- ↑ Kohara, Y et al. (1987) The physical map of the whole E. coli chromosome: application of a new strategy for rapid analysis and sorting of a large genomic library. Cell 50 495-508 PubMed
- ↑ 7.0 7.1 CGSC: The Coli Genetics Stock Center
- ↑ 8.0 8.1 The Tn10 insertion sites determined by Nichols et al. 1998 (PMID:9829956) were reannotated by alignment with E. coli K-12 genome sequence (GenBank accession NC_000913). P1 contransduction frequencies were calculated using the formula of Wu (PMID:5338813).
