frvR:Gene Product(s)

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Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.

Standard name

FrvR

Synonyms

predicted regulator[1], B3897[2][1], YiiH[2][1], FrvR[2][1] , ECK3890, JW3868, yiiH, b3897

Product description

FrvR predicted transcriptional regulator[2][3]

Putative frv operon regulator[4]

EC number (for enzymes)


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Notes

Function

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<protect> Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0003677

DNA binding

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0238

F

Seeded from EcoCyc (v14.0)

complete

GO:0005215

transporter activity

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR016152

F

Seeded from EcoCyc (v14.0)

complete

GO:0005351

sugar:hydrogen symporter activity

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR002178

F

Seeded from EcoCyc (v14.0)

complete

GO:0006350

transcription

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0804

P

Seeded from EcoCyc (v14.0)

complete

GO:0006350

transcription

PMID:8019415[5]

ISS: Inferred from Sequence or Structural Similarity

Swiss-Prot:P0A2P8

P

Seeded from EcoCyc (v14.0)

complete

GO:0006810

transport

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR002178

P

Seeded from EcoCyc (v14.0)

complete

GO:0006810

transport

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR016152

P

Seeded from EcoCyc (v14.0)

complete

GO:0009401

phosphoenolpyruvate-dependent sugar phosphotransferase system

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR002178

P

Seeded from EcoCyc (v14.0)

complete

GO:0016301

kinase activity

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0418

F

Seeded from EcoCyc (v14.0)

complete

GO:0016564

transcription repressor activity

PMID:8019415[5]

ISS: Inferred from Sequence or Structural Similarity

Swiss-Prot:P0A2P8

F

Seeded from EcoCyc (v14.0)

complete

GO:0016740

transferase activity

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0808

F

Seeded from EcoCyc (v14.0)

complete

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Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type Partner Notes References Evidence

Protein

groL

PMID:16606699[6]

Experiment(s):EBI-1146937
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Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

Compartment Description Evidence Reference/Source Notes
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Notes

Structure and Physical Properties

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<protect> Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Name
Sequence

at EcoCyc 

MLNERQLKIV DLLEQQPRTP GELAQQTGVS GRTILRDIDY LNFTLNGKAR IFASGSAGYQ
LEIFERRSFF QLLQKHDNDD RLLALLLLNT FTPRAQLASA LNLPETWVAE RLPRLKQRYE
RTCCLASRPG LGHFIDETEE KRVILLANLL RKDPFLIPLA GITRDNLQHL STACDNQHRW
PLMQGDYLSS LILAIYALRN QLTDEWPQYP GDEIKQIVEH SGLFLGDNAV RTLTGLIEKQ
HQQAQVISAD NVQGLLQRVP GIASLNIIDA QLVENITGHL LRCLAAPVWI AEHRQSSMNN
LKAAWPAAFD MSLHFITLLR EQLDIPLFDS DLIGLYFACA LERHQNERQP IILLSDQNAI
ATINQLAIER DVLNCRVIIA RSLSELVAIR EEIEPLLIIN NSHYLLDDAV NNYITVKNII
TAAGIEQIKH FLATAFIRQQ PERFFSAPGS FHYSNVRGES WQHITRQICA QLVAQHHITA
DEAQRIIARE GEGENLIVNR LAIPHCWSEQ ERRFRGFFIT LAQPVEVNNE VINHVLIACA
AADARHELKI FSYLASILCQ HPAEIIAGLT GYEAFMELLH KG
Length

582

Mol. Wt

66.001 kDa

pI

6.4 (calculated)

Extinction coefficient

56,380 - 57,630 (calc based on 12 Y, 7 W, and 10 C residues)

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Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Type Residues Description Notes References

Domain

447..581

PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2

PMID:19920124[7]

Domain

5..60

PF08279 HTH domain

PMID:19920124[7]

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Structure
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

<beststructure> gene=frvR taxon=12017 </beststructure>

Models

View models at:

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Structure figures

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Notes

Gene Product Resources

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See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type Source Notes/Reference
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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

NCBI (Protein) (EcoliWiki Page)

GI:16131737

Escherichia coli str. K-12 substr. MG1655

NCBI (Protein) (EcoliWiki Page)

GeneID:948389

Escherichia coli str. K-12 substr. MG1655

ASAP

ASAP:ABE-0012720

Escherichia coli str. K-12 substr. MG1655

UniProt (EcoliWiki Page)

UniProtKB/Swiss-Prot:P32152

Escherichia coli str. K-12 substr. MG1655

EcoCyc

EcoCyc:EG11861

Escherichia coli str. K-12 substr. MG1655

EcoGene

EcoGene:EG11861

Escherichia coli str. K-12 substr. MG1655

NCBI (Gene) (EcoliWiki Page)

GeneID:948389

Escherichia coli str. K-12 substr. MG1655

RegulonDB

RegulonDB:ECK120001792

Escherichia coli str. K-12 substr. MG1655

EchoBASE

EchoBASE:EB1807

Escherichia coli str. K-12 substr. MG1655

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Notes

Links

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References

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See Help:References for how to manage references in EcoliWiki.

  1. ↑ 1.0 1.1 1.2 1.3 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  5. ↑ 5.0 5.1 Reizer, J et al. (1994) Novel phosphotransferase system genes revealed by bacterial genome analysis: unique, putative fructose- and glucoside-specific systems. Protein Sci. 3 440-50 PubMed
  6. ↑ Arifuzzaman, M et al. (2006) Large-scale identification of protein-protein interaction of Escherichia coli K-12. Genome Res. 16 686-91 PubMed
  7. ↑ 7.0 7.1 Finn, RD et al. (2010) The Pfam protein families database. Nucleic Acids Res. 38 D211-22 PubMed

Categories

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