fliK:Gene Product(s)

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Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.

Standard name

FliK

Synonyms

flagellar hook-length control protein[1], B1943[2][1], FlaR[2][1], FlaE[2][1], FliK[2][1] , ECK1941, flaE, JW1927, b1943

Product description

flagellar hook-length control protein FliK[2][3]

EC number (for enzymes)


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Notes

Function

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<protect> Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0003774

motor activity

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001635

F

Seeded from EcoCyc (v14.0)

complete

GO:0009296

flagellum assembly

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001635

P

Seeded from EcoCyc (v14.0)

complete

GO:0009424

bacterial-type flagellum hook

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001635

C

Seeded from EcoCyc (v14.0)

complete

GO:0071973

bacterial-type flagellar cell motility

PMID:8631687[4]

IMP: Inferred from Mutant Phenotype

P

complete

GO:0009424

bacterial-type flagellum hook

PMID:16949608[5]

IMP: Inferred from Mutant Phenotype

C

complete

Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type Partner Notes References Evidence

Protein

rsuA

PMID:16606699[6]

Experiment(s):EBI-1141461

Protein

cydC

PMID:16606699[6]

Experiment(s):EBI-1141461

Protein

pinE

PMID:16606699[6]

Experiment(s):EBI-1141461

Protein

nuoE

PMID:16606699[6]

Experiment(s):EBI-1141461

Protein

nadE

PMID:16606699[6]

Experiment(s):EBI-1141461

Protein

purL

PMID:16606699[6]

Experiment(s):EBI-1141461

Protein

dnaK

PMID:16606699[6]

Experiment(s):EBI-1141461

Protein

rhsC

PMID:16606699[6]

Experiment(s):EBI-1141461

Protein

rpsA

PMID:16606699[6]

Experiment(s):EBI-1141461

Protein

rplF

PMID:16606699[6]

Experiment(s):EBI-1141461

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Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

Compartment Description Evidence Reference/Source Notes

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Notes

Structure and Physical Properties

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<protect> Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Name
Sequence

at EcoCyc

MIRLAPLITA DVDTTTLPGG KASDAAQDFL ALLSEALAGE TTTDKAAPQL LVATDKPTTK
GEPLISDIVS DAQQANLLIP VDETPPVIND EQSTSTPLTT AQTMALAAVA DKNTTKDEKA
DDLNEDVTAS LSALFAMLPG FDNTPKVTDA PSTVLPTEKP TLFTKLTSEQ LTTAQPDDAP
GTPAQPLTPL VAEAQSKAEV ISTPSPVTAA ASPLITPHQT QPLPTVAAPV LSAPLGSHEW
QQSLSQHISL FTRQGQQSAE LRLHPQDLGE VQISLKVDDN QAQIQMVSPH QHVRAALEAA
LPVLRTQLAE SGIQLGQSNI SGESFSGQQQ AASQQQQSQR TANHEPLAGE DDDTLPVPVS
LQGRVTGNSG VDIFA
Length

375

Mol. Wt

39.311 kDa

pI

4.2 (calculated)

Extinction coefficient

5,500 (calc based on 0 Y, 1 W, and 0 C residues)


Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Type Residues Description Notes References

Domain

245..336

PF02120 Flagellar hook-length control protein FliK

PMID:19920124[7]

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Structure
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

<beststructure> gene=fliK taxon=562,83333 </beststructure>

Models

View models at:

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Structure figures

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Notes

Gene Product Resources

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See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type Source Notes/Reference

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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

NCBI (Protein) (EcoliWiki Page)

GI:16129890

Escherichia coli str. K-12 substr. MG1655

NCBI (Protein) (EcoliWiki Page)

GeneID:946449

Escherichia coli str. K-12 substr. MG1655

ASAP

ASAP:ABE-0006464

Escherichia coli str. K-12 substr. MG1655

UniProt (EcoliWiki Page)

UniProtKB/Swiss-Prot:P52614

Escherichia coli str. K-12 substr. MG1655

EcoCyc

EcoCyc:G379

Escherichia coli str. K-12 substr. MG1655

EcoGene

EcoGene:EG20268

Escherichia coli str. K-12 substr. MG1655

NCBI (Gene) (EcoliWiki Page)

GeneID:946449

Escherichia coli str. K-12 substr. MG1655

RegulonDB

RegulonDB:ECK120002694

Escherichia coli str. K-12 substr. MG1655

EchoBASE

EchoBASE:EB4165

Escherichia coli str. K-12 substr. MG1655

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Notes

Links

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References

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See Help:References for how to manage references in EcoliWiki.

  1. 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 2.2 2.3 2.4 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. Kawagishi, I et al. (1996) Characterization of the flagellar hook length control protein fliK of Salmonella typhimurium and Escherichia coli. J. Bacteriol. 178 2954-9 PubMed
  5. Minamino, T et al. (2006) Two parts of the T3S4 domain of the hook-length control protein FliK are essential for the substrate specificity switching of the flagellar type III export apparatus. J. Mol. Biol. 362 1148-58 PubMed
  6. 6.0 6.1 6.2 6.3 6.4 6.5 6.6 6.7 6.8 6.9 Arifuzzaman, M et al. (2006) Large-scale identification of protein-protein interaction of Escherichia coli K-12. Genome Res. 16 686-91 PubMed
  7. Finn, RD et al. (2010) The Pfam protein families database. Nucleic Acids Res. 38 D211-22 PubMed

Categories

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