flhA:Gene Product(s)

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Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.

Standard name

FlhA

Synonyms

predicted flagellar export pore protein[1], B1879[2][1], FlaH[2][1], FlhA[2][1] , ECK1880, flaH, JW1868, b1879

Product description

flagellar biosynthesis protein FlhA[2][3];

Component of Flagellar Export Apparatus[3]; Flagellum[3]

Flagellar export pore protein, integral membrane protein[4]

EC number (for enzymes)


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Notes

Function

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<protect> Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0005886

plasma membrane

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0997

C

Seeded from EcoCyc (v14.0)

complete

GO:0005886

plasma membrane

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-1003

C

Seeded from EcoCyc (v14.0)

complete

GO:0006810

transport

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0813

P

Seeded from EcoCyc (v14.0)

complete

GO:0009306

protein secretion

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001712

P

Seeded from EcoCyc (v14.0)

complete

GO:0015031

protein transport

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR006301

P

Seeded from EcoCyc (v14.0)

complete

GO:0015031

protein transport

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0653

P

Seeded from EcoCyc (v14.0)

complete

GO:0016020

membrane

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001712

C

Seeded from EcoCyc (v14.0)

complete

GO:0016020

membrane

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0472

C

Seeded from EcoCyc (v14.0)

complete

GO:0016021

integral to membrane

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR006301

C

Seeded from EcoCyc (v14.0)

complete

GO:0016021

integral to membrane

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0812

C

Seeded from EcoCyc (v14.0)

complete

GO:0016021

integral to membrane

GO_REF:0000023

IEA: Inferred from Electronic Annotation

SP_SL:SL-9909

C

Seeded from EcoCyc (v14.0)

complete

GO:0009296

flagellum assembly

PMID:7007337[5]

IMP: Inferred from Mutant Phenotype

P

complete

GO:0019861

flagellum

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR006301

C

Seeded from EcoCyc (v14.0)

complete

Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type Partner Notes References Evidence

Protein

Subunits of Flagellar Export Apparatus

could be indirect

Protein

Subunits of Flagellum

could be indirect


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Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

Compartment Description Evidence Reference/Source Notes

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Notes

Structure and Physical Properties

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<protect> Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Name
Sequence

at EcoCyc

MSNLAAMLRL PANLKSTQWQ ILAGPILILL ILSMMVLPLP AFILDLLFTF NIALSIMVLL
VAMFTQRTLE FAAFPTILLF TTLLRLALNV ASTRIILMEG HTGAAAAGKV VEAFGHFLVG
GNFAIGIVVF VILVIINFMV ITKGAGRIAE VGARFVLDGM PGKQMAIDAD LNAGLIGEDE
AKKRRSEVTQ EADFYGSMDG ASKFVRGDAI AGILIMVINI VGGLLVGVLQ HGMSMGHAAE
SYTLLTIGDG LVAQIPALVI STAAGVIVTR VSTDQDVGEQ MVNQLFSNPS VMLLSAAVLG
LLGLVPGMPN LVFLLFTAGL LGLAWWIRGR EQKAPAEPKP VKMAENNTVV EATWNDVQLE
DSLGMEVGYR LIPMVDFQQD GELLGRIRSI RKKFAQEMGF LPPVVHIRDN MDLQPARYRI
LMKGVEIGSG DAYPGRWLAI NPGTAAGTLP GEATVDPAFG LNAIWIESAL KEQAQIQGYT
VVEASTVVAT HLNHLISQHA AELFGRQEAQ QLLDRVAQEM PKLTEDLVPG VVTLTTLHKV
LQNLLDEKVP IRDMRTILET LAEHAPIQSD PHELTAVVRV ALGRAITQQW FPGKDEVHVI
GLDTPLERLL LQALQGGGGL EPGLADRLLA QTQEALSRQE MLGAPPVLLV NHALRPLLSR
FLRRSLPQLV VLSNLELSDN RHIRMTATIG GK
Length

692

Mol. Wt

74.844 kDa

pI

6.1 (calculated)

Extinction coefficient

47,440 (calc based on 6 Y, 7 W, and 0 C residues)


Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Type Residues Description Notes References

Domain

30..683

PF00771 FHIPEP family

PMID:19920124[6]

<motif_map/>

tmhmm.php?gene=flhA&show=pic&.jpg
Click the image to view raw output from TMHMM.

Structure
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

<beststructure> gene=flhA taxon=562,83333 </beststructure>

Models

View models at:

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Structure figures

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Notes

Gene Product Resources

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See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type Source Notes/Reference

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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

NCBI (Protein) (EcoliWiki Page)

GI:16129831

Escherichia coli str. K-12 substr. MG1655

NCBI (Protein) (EcoliWiki Page)

GeneID:946390

Escherichia coli str. K-12 substr. MG1655

ASAP

ASAP:ABE-0006272

Escherichia coli str. K-12 substr. MG1655

UniProt (EcoliWiki Page)

UniProtKB/Swiss-Prot:P76298

Escherichia coli str. K-12 substr. MG1655

EcoCyc

EcoCyc:G370

Escherichia coli str. K-12 substr. MG1655

EcoGene

EcoGene:EG14273

Escherichia coli str. K-12 substr. MG1655

NCBI (Gene) (EcoliWiki Page)

GeneID:946390

Escherichia coli str. K-12 substr. MG1655

RegulonDB

RegulonDB:ECK120002690

Escherichia coli str. K-12 substr. MG1655

EchoBASE

EchoBASE:EB4021

Escherichia coli str. K-12 substr. MG1655

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Notes

Links

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References

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See Help:References for how to manage references in EcoliWiki.

  1. 1.0 1.1 1.2 1.3 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 2.2 2.3 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. 3.0 3.1 3.2 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  5. Suzuki, T & Komeda, Y (1981) Incomplete flagellar structures in Escherichia coli mutants. J. Bacteriol. 145 1036-41 PubMed
  6. Finn, RD et al. (2010) The Pfam protein families database. Nucleic Acids Res. 38 D211-22 PubMed

Categories

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