flgK:Gene Product(s)

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Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.

Standard name

FlgK

Synonyms

flagellar hook-filament junction protein 1[1], B1082[2][1], FlaW[2][1], FlaS[2][1], FlgK[2][1] , ECK1067, flaS, JW1069, b1082

Product description

flagellar biosynthesis, hook-filament junction protein 1[2][3];

Component of Flagellum[3]

Flagellar synthesis, hook-associated protein[4]

EC number (for enzymes)


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Notes

Function

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<protect> Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0001539

ciliary or flagellar motility

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001444

P

Seeded from EcoCyc (v14.0)

complete

GO:0003774

motor activity

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001444

F

Seeded from EcoCyc (v14.0)

complete

GO:0005198

structural molecule activity

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001444

F

Seeded from EcoCyc (v14.0)

complete

GO:0005198

structural molecule activity

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR002371

F

Seeded from EcoCyc (v14.0)

complete

GO:0005576

extracellular region

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0964

C

Seeded from EcoCyc (v14.0)

complete

GO:0005576

extracellular region

GO_REF:0000023

IEA: Inferred from Electronic Annotation

SP_SL:SL-0243

C

Seeded from EcoCyc (v14.0)

complete

GO:0009288

bacterial-type flagellum

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001444

C

Seeded from EcoCyc (v14.0)

complete

GO:0009288

bacterial-type flagellum

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0975

C

Seeded from EcoCyc (v14.0)

complete

GO:0009288

bacterial-type flagellum

GO_REF:0000023

IEA: Inferred from Electronic Annotation

SP_SL:SL-0307

C

Seeded from EcoCyc (v14.0)

complete

GO:0009296

flagellum assembly

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR002371

P

Seeded from EcoCyc (v14.0)

complete

GO:0009424

bacterial-type flagellum hook

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR002371

C

Seeded from EcoCyc (v14.0)

complete

GO:0009296

flagellum assembly

PMID:7007337[5]

IMP: Inferred from Mutant Phenotype

P

complete

GO:0019861

flagellum

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR010930

C

Seeded from EcoCyc (v14.0)

complete

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Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type Partner Notes References Evidence

Protein

Subunits of Flagellum

could be indirect

Protein

rpsB

PMID:16606699[6]

Experiment(s):EBI-1138791
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Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

Compartment Description Evidence Reference/Source Notes
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Notes

Structure and Physical Properties

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<protect> Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Name
Sequence

at EcoCyc 

MSSLINNAMS GLNAAQAALN TASNNISSYN VAGYTRQTTI MAQANSTLGA GGWVGNGVYV
SGVQREYDAF ITNQLRAAQT QSSGLTARYE QMSKIDNMLS TSTSSLATQM QDFFTSLQTL
VSNAEDPAAR QALIGKSEGL VNQFKTTDQY LRDQDKQVNI AIGASVDQIN NYAKQIASLN
DQISRLTGVG AGASPNNLLD QRDQLVSELN QIVGVEVSVQ DGGTYNITMA NGYSLVQGST
ARQLAAVPSS ADPSRTTVAY VDGTAGNIEI PEKLLNTGSL GGILTFRSQD LDQTRNTLGQ
LALAFAEAFN TQHKAGFDAN GDAGEDFFAI GKPAVLQNTK NKGDVAIGAT VTDASAVLAT
DYKISFDNNQ WQVTRLASNT TFTVTPDANG KVAFDGLELT FTGTPAVNDS FTLKPVSDAI
VNMDVLITDE AKIAMASEED AGDSDNRNGQ ALLDLQSNSK TVGGAKSFND AYASLVSDIG
NKTATLKTSS ATQGNVVTQL SNQQQSISGV NLDEEYGNLQ RFQQYYLANA QVLQTANAIF
DALINIR
Length

547

Mol. Wt

57.93 kDa

pI

4.3 (calculated)

Extinction coefficient

33,350 (calc based on 15 Y, 2 W, and 0 C residues)

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Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Type Residues Description Notes References

Initiator Methionine

1

Removed (By similarity)

UniProt:P33235

Domain

5..35

PF00460 Flagella basal body rod protein

PMID:19920124[7]

Domain

508..546

PF06429 Domain of unknown function (DUF1078)

PMID:19920124[7]

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Structure
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

<beststructure> gene=flgK taxon=562,83333 </beststructure>

Models

View models at:

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Structure figures

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Notes

Gene Product Resources

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See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type Source Notes/Reference
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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

NCBI (Protein) (EcoliWiki Page)

GI:16129045

Escherichia coli str. K-12 substr. MG1655

NCBI (Protein) (EcoliWiki Page)

GeneID:945648

Escherichia coli str. K-12 substr. MG1655

ASAP

ASAP:ABE-0003660

Escherichia coli str. K-12 substr. MG1655

UniProt (EcoliWiki Page)

UniProtKB/Swiss-Prot:P33235

Escherichia coli str. K-12 substr. MG1655

EcoCyc

EcoCyc:EG11967

Escherichia coli str. K-12 substr. MG1655

EcoGene

EcoGene:EG11967

Escherichia coli str. K-12 substr. MG1655

NCBI (Gene) (EcoliWiki Page)

GeneID:945648

Escherichia coli str. K-12 substr. MG1655

RegulonDB

RegulonDB:ECK120001893

Escherichia coli str. K-12 substr. MG1655

EchoBASE

EchoBASE:EB1910

Escherichia coli str. K-12 substr. MG1655

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Notes

Links

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References

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See Help:References for how to manage references in EcoliWiki.

  1. ↑ 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 2.4 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  5. ↑ Suzuki, T & Komeda, Y (1981) Incomplete flagellar structures in Escherichia coli mutants. J. Bacteriol. 145 1036-41 PubMed
  6. ↑ Arifuzzaman, M et al. (2006) Large-scale identification of protein-protein interaction of Escherichia coli K-12. Genome Res. 16 686-91 PubMed
  7. ↑ 7.0 7.1 Finn, RD et al. (2010) The Pfam protein families database. Nucleic Acids Res. 38 D211-22 PubMed

Categories

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