fes:Gene Product(s)

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Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.

Standard name

Fes

Synonyms

enterobactin/ferric enterobactin esterase[1], B0585[2][1], Fes[2][1], enterobactin esterase[2][1] , ECK0577, JW0576, b0585

Product description

enterochelin esterase[2][3]

Enterochelin esterase[4]

EC number (for enzymes)


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Notes

Function

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<protect> Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status

NOT

GO:0005506

iron ion binding

GOA:spkw SP_KW:GO_REF

IEA: Inferred from Electronic Annotation

SP_KW:KW-0408


F

Fes binds enterochelin and ferric-enterochelin.[5] There is no experimental evidence that Fes binds iron. 127.0.0.1 14:27, 17 February 2015 (CST)

complete

GO:0008849

enterochelin esterase activity

PMID:150859[5]

IDA: Inferred from Direct Assay

F

complete

GO:0005737

cytoplasm

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0963

C

Seeded from EcoCyc (v14.0)

complete

GO:0005737

cytoplasm

GO_REF:0000023

IEA: Inferred from Electronic Annotation

SP_SL:SL-0086

C

Seeded from EcoCyc (v14.0)

complete

NOT

GO:0006826

iron ion transport

SP_KW:GO_REF GOA:spkw

IEA: Inferred from Electronic Annotation

SP_KW:KW-0410


P

Fes is involved in iron ion transport; it cleaves ferric-enterochelin after it has been transported into the cytoplasm.[5] 127.0.0.1 14:27, 17 February 2015 (CST)

complete

Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type Partner Notes References Evidence

Protein

xseA

PMID:16606699[6]

Experiment(s):EBI-1137234

Protein

hcaE

PMID:16606699[6]

Experiment(s):EBI-1137234

Protein

nuoF

PMID:16606699[6]

Experiment(s):EBI-1137234

Protein

groL

PMID:16606699[6]

Experiment(s):EBI-1137234

Protein

ahpF

PMID:19402753[7]

MALDI(Z-score):28.802552

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Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

Compartment Description Evidence Reference/Source Notes

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Notes

Structure and Physical Properties

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<protect> Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Name
Sequence

at EcoCyc

MFEVTFWWRD PQGSEEYSTI KRVWVYITGV TDHHQNSQPQ SMQRIAGTNV WQWTTQLNAN
WRGSYCFIPT ERDDIFSVPS PDRLELREGW RKLLPQAIAD PLNLQSWKGG RGHAVSALEM
PQAPLQPGWD CPQAPEIPAK EIIWKSERLK KSRRVWIFTT GDATAEERPL AVLLDGEFWA
QSMPVWPVLT SLTHRQQLPP AVYVLIDAID TTHRAHELPC NADFWLAVQQ ELLPLVKAIA
PFSDRADRTV VAGQSFGGLS ALYAGLHWPE RFGCVLSQSG SYWWPHRGGQ QEGVLLEKLK
AGEVSAEGLR IVLEAGIREP MIMRANQALY AQLHPIKESI FWRQVDGGHD ALCWRGGLMQ
GLIDLWQPLF HDRS
Length

374

Mol. Wt

42.569 kDa

pI

6.6 (calculated)

Extinction coefficient

120,430 - 121,055 (calc based on 7 Y, 20 W, and 5 C residues)


Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Type Residues Description Notes References

Domain

146..365

PF00756 Putative esterase

PMID:19920124[8]

Domain

1..131

PF11806 Domain of unknown function (DUF3327)

PMID:19920124[8]

<motif_map/>

Structure
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

<beststructure> gene=fes taxon=562,83333 </beststructure>

Models

View models at:

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Structure figures

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Notes

Gene Product Resources

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See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type Source Notes/Reference

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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

NCBI (Protein) (EcoliWiki Page)

GI:16128568

Escherichia coli str. K-12 substr. MG1655

NCBI (Protein) (EcoliWiki Page)

GeneID:945181

Escherichia coli str. K-12 substr. MG1655

ASAP

ASAP:ABE-0002019

Escherichia coli str. K-12 substr. MG1655

UniProt (EcoliWiki Page)

UniProtKB/Swiss-Prot:P13039

Escherichia coli str. K-12 substr. MG1655

EcoCyc

EcoCyc:EG10299

Escherichia coli str. K-12 substr. MG1655

EcoGene

EcoGene:EG10299

Escherichia coli str. K-12 substr. MG1655

NCBI (Gene) (EcoliWiki Page)

GeneID:945181

Escherichia coli str. K-12 substr. MG1655

RegulonDB

RegulonDB:ECK120000293

Escherichia coli str. K-12 substr. MG1655

EchoBASE

EchoBASE:EB0295

Escherichia coli str. K-12 substr. MG1655

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Notes

Links

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References

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See Help:References for how to manage references in EcoliWiki.

  1. 1.0 1.1 1.2 1.3 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 2.2 2.3 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  5. 5.0 5.1 5.2 Greenwood, KT & Luke, RK (1978) Enzymatic hydrolysis of enterochelin and its iron complex in Escherichia Coli K-12. Properties of enterochelin esterase. Biochim. Biophys. Acta 525 209-18 PubMed
  6. 6.0 6.1 6.2 6.3 Arifuzzaman, M et al. (2006) Large-scale identification of protein-protein interaction of Escherichia coli K-12. Genome Res. 16 686-91 PubMed
  7. Hu, P et al. (2009) Global functional atlas of Escherichia coli encompassing previously uncharacterized proteins. PLoS Biol. 7 e96 PubMed
  8. 8.0 8.1 Finn, RD et al. (2010) The Pfam protein families database. Nucleic Acids Res. 38 D211-22 PubMed

Categories

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