feaR:Gene Product(s)

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Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.

Standard name

FeaR

Synonyms

DNA-binding transcriptional dual regulator[1], B1384[2][1], MaoX[2][1], YdbM[2][1], MaoB[2][1], FeaR[2][1] , ECK1381, JW1379, maoB, maoR, maoX, ydbM, b1384

Product description

FeaR transcriptional regulator[2]; FeaR transcriptional activator[3]

Transcriptional activator for tynA and feaB, AraC family[4]

EC number (for enzymes)


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Notes

Function

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<protect> Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0003700

transcription factor activity

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000005

F

Seeded from EcoCyc (v14.0)

complete

GO:0003700

transcription factor activity

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR020449

F

Seeded from EcoCyc (v14.0)

complete

GO:0003700

transcription factor activity

PMID:8631685[5]

IDA: Inferred from Direct Assay

F

Seeded from EcoCyc (v14.0)

complete

GO:0003700

transcription factor activity

PMID:9043126[6]

ISS: Inferred from Sequence or Structural Similarity

Swiss-Prot:P07859
Swiss-Prot:P09378
Swiss-Prot:P09377
Swiss-Prot:P03021
Swiss-Prot:P10411

F

Seeded from EcoCyc (v14.0)

complete

GO:0005622

intracellular

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000005

C

Seeded from EcoCyc (v14.0)

complete

GO:0005622

intracellular

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR020449

C

Seeded from EcoCyc (v14.0)

complete

GO:0016563

transcription activator activity

PMID:8631685[5]

IDA: Inferred from Direct Assay

F

Seeded from EcoCyc (v14.0)

complete

GO:0016563

transcription activator activity

PMID:9043126[6]

ISS: Inferred from Sequence or Structural Similarity

Swiss-Prot:P07859
Swiss-Prot:P09378
Swiss-Prot:P09377
Swiss-Prot:P03021
Swiss-Prot:P10411

F

Seeded from EcoCyc (v14.0)

complete

GO:0043193

positive regulation of gene-specific transcription

PMID:8631685[5]

IDA: Inferred from Direct Assay

P

Seeded from EcoCyc (v14.0)

complete

GO:0043193

positive regulation of gene-specific transcription

PMID:9043126[6]

ISS: Inferred from Sequence or Structural Similarity

Swiss-Prot:P07859
Swiss-Prot:P09378
Swiss-Prot:P09377
Swiss-Prot:P03021
Swiss-Prot:P10411

P

Seeded from EcoCyc (v14.0)

complete

GO:0043565

sequence-specific DNA binding

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000005

F

Seeded from EcoCyc (v14.0)

complete

GO:0043565

sequence-specific DNA binding

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR020449

F

Seeded from EcoCyc (v14.0)

complete

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Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type Partner Notes References Evidence

Protein

sdhA

PMID:16606699[7]

Experiment(s):EBI-1139735

Protein

groL

PMID:16606699[7]

Experiment(s):EBI-1139735
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Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

Compartment Description Evidence Reference/Source Notes
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Notes

Structure and Physical Properties

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<protect> Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Name
Sequence

at EcoCyc 

MNPAVDNEFQ QWLSQINQVC GNFTGRLLTE RYTGVLDTHF AKGLKLSTVT TSGVNLSRTW
QEVKGSDDAW FYTVFQLSGQ AIMEQDERQV QIGAGDITLL DASRPCSLYW QESSKQISLL
LPRTLLEQYF PHQKPICAER LDADLPMVQL SHRLLQESMN NPALSETESE AALQAMVCLL
RPVLHQRESV QPRRERQFQK VVTLIDDNIR EEILRPEWIA GETGMSVRSL YRMFADKGLV
VAQYIRNRRL DFCADAIRHA ADDEKLAGIG FHWGFSDQSH FSTVFKQRFG MTPGEYRRKF R
Length

301

Mol. Wt

34.62 kDa

pI

6.9 (calculated)

Extinction coefficient

43,430 - 44,055 (calc based on 7 Y, 6 W, and 5 C residues)

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Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Type Residues Description Notes References

Domain

257..298

PF00165 Bacterial regulatory helix-turn-helix proteins, AraC family

PMID:19920124[8]

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Structure
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

<beststructure> gene=feaR taxon=562,83333 </beststructure>

Models

View models at:

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Structure figures

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Notes

Gene Product Resources

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See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type Source Notes/Reference
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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

NCBI (Protein) (EcoliWiki Page)

GI:16129345

Escherichia coli str. K-12 substr. MG1655

NCBI (Protein) (EcoliWiki Page)

GeneID:945941

Escherichia coli str. K-12 substr. MG1655

ASAP

ASAP:ABE-0004630

Escherichia coli str. K-12 substr. MG1655

UniProt (EcoliWiki Page)

UniProtKB/Swiss-Prot:Q47129

Escherichia coli str. K-12 substr. MG1655

EcoCyc

EcoCyc:G6706

Escherichia coli str. K-12 substr. MG1655

EcoGene

EcoGene:EG13422

Escherichia coli str. K-12 substr. MG1655

NCBI (Gene) (EcoliWiki Page)

GeneID:945941

Escherichia coli str. K-12 substr. MG1655

RegulonDB

RegulonDB:ECK120003301

Escherichia coli str. K-12 substr. MG1655

EchoBASE

EchoBASE:EB3198

Escherichia coli str. K-12 substr. MG1655

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Notes

Links

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References

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See Help:References for how to manage references in EcoliWiki.

  1. ↑ 1.0 1.1 1.2 1.3 1.4 1.5 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 2.4 2.5 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  5. ↑ 5.0 5.1 5.2 Yamashita, M et al. (1996) maoB, a gene that encodes a positive regulator of the monoamine oxidase gene (maoA) in Escherichia coli. J. Bacteriol. 178 2941-7 PubMed
  6. ↑ 6.0 6.1 6.2 Hanlon, SP et al. (1997) 2-phenylethylamine catabolism by Escherichia coli K-12: gene organization and expression. Microbiology (Reading, Engl.) 143 ( Pt 2) 513-8 PubMed
  7. ↑ 7.0 7.1 Arifuzzaman, M et al. (2006) Large-scale identification of protein-protein interaction of Escherichia coli K-12. Genome Res. 16 686-91 PubMed
  8. ↑ Finn, RD et al. (2010) The Pfam protein families database. Nucleic Acids Res. 38 D211-22 PubMed

Categories

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