entS:Gene Product(s)

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Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.

Standard name

EntS

Synonyms

predicted transporter[1], B0591[2][1], EntS[2][1], YbdA[2][1] , ECK0584, JW0583, ybdA, b0591

Product description

EntS MFS transporter[2][3];

Component of EntS-TolC Enterobactin Efflux Transport System[3]

Enterobactin exporter; iron-regulated[4]

EC number (for enzymes)


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Notes

Function

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<protect> Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0005886

plasma membrane

GOA:hamap
GO_REF:0000020

IEA: Inferred from Electronic Annotation

HAMAP:MF_01436

C

Seeded from EcoCyc (v14.0)

complete

GO:0042930

enterobactin transport

PMID:16166532[5]

IMP: Inferred from Mutant Phenotype

P

See discussion tab for discussion of why the IGI evidence code was changed to IMP.

complete

GO:0005886

plasma membrane

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0997

C

Seeded from EcoCyc (v14.0)

complete

GO:0005886

plasma membrane

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-1003

C

Seeded from EcoCyc (v14.0)

complete

GO:0016020

membrane

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0472

C

Seeded from EcoCyc (v14.0)

complete

GO:0016021

integral to membrane

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0812

C

Seeded from EcoCyc (v14.0)

complete

GO:0016021

integral to membrane

GO_REF:0000023

IEA: Inferred from Electronic Annotation

SP_SL:SL-9909

C

Seeded from EcoCyc (v14.0)

complete

Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type Partner Notes References Evidence

Protein

Subunits of EntS-TolC Enterobactin Efflux Transport System

could be indirect


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Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

Compartment Description Evidence Reference/Source Notes

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Notes

Structure and Physical Properties

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<protect> Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Name
Sequence

at EcoCyc

MNKQSWLLNL SLLKTHPAFR AVFLARFISI VSLGLLGVAV PVQIQMMTHS TWQVGLSVTL
TGGAMFVGLM VGGVLADRYE RKKVILLARG TCGIGFIGLC LNALLPEPSL LAIYLLGLWD
GFFASLGVTA LLAATPALVG RENLMQAGAI TMLTVRLGSV ISPMIGGLLL ATGGVAWNYG
LAAAGTFITL LPLLSLPALP PPPQPREHPL KSLLAGFRFL LASPLVGGIA LLGGLLTMAS
AVRVLYPALA DNWQMSAAQI GFLYAAIPLG AAIGALTSGK LAHSARPGLL MLLSTLGSFL
AIGLFGLMPM WILGVVCLAL FGWLSAVSSL LQYTMLQTQT PEAMLGRING LWTAQNVTGD
AIGAALLGGL GAMMTPVASA SASGFGLLII GVLLLLVLVE LRHFRQTPPQ VTASDS
Length

416

Mol. Wt

43.284 kDa

pI

10.2 (calculated)

Extinction coefficient

52,940 - 53,315 (calc based on 6 Y, 8 W, and 3 C residues)


Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Type Residues Description Notes References

Domain

12..414

PF05977 Bacterial protein of unknown function (DUF894)

PMID:19920124[6]

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Structure
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

<beststructure> gene=entS taxon=562,83333 </beststructure>

Models

View models at:

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Structure figures

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Notes

Gene Product Resources

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See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type Source Notes/Reference

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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

NCBI (Protein) (EcoliWiki Page)

GI:16128574

Escherichia coli str. K-12 substr. MG1655

NCBI (Protein) (EcoliWiki Page)

GeneID:946268

Escherichia coli str. K-12 substr. MG1655

ASAP

ASAP:ABE-0002036

Escherichia coli str. K-12 substr. MG1655

UniProt (EcoliWiki Page)

UniProtKB/Swiss-Prot:P24077

Escherichia coli str. K-12 substr. MG1655

EcoCyc

EcoCyc:EG11104

Escherichia coli str. K-12 substr. MG1655

EcoGene

EcoGene:EG11104

Escherichia coli str. K-12 substr. MG1655

NCBI (Gene) (EcoliWiki Page)

GeneID:946268

Escherichia coli str. K-12 substr. MG1655

RegulonDB

RegulonDB:ECK120001092

Escherichia coli str. K-12 substr. MG1655

EchoBASE

EchoBASE:EB1096

Escherichia coli str. K-12 substr. MG1655

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Notes

Links

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References

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See Help:References for how to manage references in EcoliWiki.

  1. 1.0 1.1 1.2 1.3 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 2.2 2.3 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  5. Bleuel, C et al. (2005) TolC is involved in enterobactin efflux across the outer membrane of Escherichia coli. J. Bacteriol. 187 6701-7 PubMed
  6. Finn, RD et al. (2010) The Pfam protein families database. Nucleic Acids Res. 38 D211-22 PubMed

Categories

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