cvrA:Gene Product(s)

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Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

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Standard name

CvrA

Synonyms

predicted cation/proton antiporter[1], B1191[2][1], CvrA[2][1], YcgO[2][1] , ECK1179, JW5184, ycgO, b1191

Product description

YcgO CPA1 Transporter[2][3]

Required for growth at low osmolarity; similar to eukaryotic Na+/H+ exchangers, but not involved in Na+ extrusion; proposed to be involved in the regulation of cell volume[4]

EC number (for enzymes)


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Notes

Function

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<protect> Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status

Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type Partner Notes References Evidence

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Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

Compartment Description Evidence Reference/Source Notes

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Notes

Structure and Physical Properties

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<protect> Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Name
Sequence

at EcoCyc

MLAGVDGVGG IPFDNYPFAY MVSNLALAII LLDGGMRTQA SSFRVALGPA LSLATLGVLI
TSGLTGMMAA WLFNLDLIEG LLIGAIVGST DAAAVFSLLG GKGLNERVGS TLEIESGSND
PMAVFLTITL IAMIQHHESN ISWMFIVDIL QQFGLGIVIG LGGGYLLLQM INRIALPAGL
YPLLALSGGI LIFSLTTALE GSGILAVYLC GFLLGNRPIR NRYGILQNFD GLAWLAQIAM
FLVLGLLVNP SDLLPIAIPA LILSAWMIFF ARPLSVFAGL LPFRGFNLRE RVFISWVGLR
GAVPIILAVF PMMAGLENAR LFFNVAFFVV LVSLLLQGTS LSWAAKKAKV VVPPVGRPVS
RVGLDIHPEN PWEQFVYQLS ADKWCVGAAL RDLHMPKETR IAALFRDNQL LHPTGSTRLR
EGDVLCVIGR ERDLPALGKL FSQSPPVALD QRFFGDFILE ASAKYADVAL IYGLEDGREY
RDKQQTLGEI VQQLLGAAPV VGDQVEFAGM IWTVAEKEDN EVLKIGVRVA EEEAES
Length

536

Mol. Wt

57.911 kDa

pI

5.1 (calculated)

Extinction coefficient

64,400 - 64,775 (calc based on 10 Y, 9 W, and 3 C residues)


Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Type Residues Description Notes References

Domain

492..573

PF03471 Transporter associated domain

PMID:19920124[5]

Domain

10..389

PF00999 Sodium/hydrogen exchanger family

PMID:19920124[5]

Domain

417..484

PF02080 TrkA-C domain

PMID:19920124[5]

<motif_map/>

tmhmm.php?gene=cvrA&show=pic&.jpg
Click the image to view raw output from TMHMM.

Structure
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

<beststructure> gene=cvrA taxon=562,83333 </beststructure>

Models

View models at:

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Structure figures

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Notes

Gene Product Resources

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See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type Source Notes/Reference

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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

NCBI (Protein) (EcoliWiki Page)

GI:90111230

Escherichia coli str. K-12 substr. MG1655

NCBI (Protein) (EcoliWiki Page)

GeneID:945755

Escherichia coli str. K-12 substr. MG1655

ASAP

ASAP:ABE-0003999

Escherichia coli str. K-12 substr. MG1655

UniProt (EcoliWiki Page)

UniProtKB/Swiss-Prot:P76007

Escherichia coli str. K-12 substr. MG1655

EcoCyc

EcoCyc:G6620

Escherichia coli str. K-12 substr. MG1655

EcoGene

EcoGene:EG13896

Escherichia coli str. K-12 substr. MG1655

NCBI (Gene) (EcoliWiki Page)

GeneID:945755

Escherichia coli str. K-12 substr. MG1655

RegulonDB

RegulonDB:ECK120003215

Escherichia coli str. K-12 substr. MG1655

EchoBASE

EchoBASE:EB3655

Escherichia coli str. K-12 substr. MG1655

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Notes

Links

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References

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See Help:References for how to manage references in EcoliWiki.

  1. 1.0 1.1 1.2 1.3 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 2.2 2.3 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  5. 5.0 5.1 5.2 Finn, RD et al. (2010) The Pfam protein families database. Nucleic Acids Res. 38 D211-22 PubMed

Categories

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