cspC:Gene Product(s)
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| Nomenclature | Function | Interactions | Localization | Sequence | Domains | Structure | Resources | Accessions | Links | References | Suggestions |
Nomenclature
See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.
| Standard name |
CspC |
|---|---|
| Synonyms |
stress protein, member of the CspA-family[1], B1823[2][1], MsmB[2][1], CspC[2][1] , ECK1821, JW1812, msmB, b1823 |
| Product description |
stress protein, member of the CspA family[2]; stress protein, member of the CspA family; predicted DNA-binding transcriptional regulator[3] Multicopy suppressor of mukB; cold shock protein homolog constitutively expressed at 37C; affects rpoS and uspA expression[4] |
| EC number (for enzymes) |
|
| edit table |
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Notes
Function
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Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0001072 |
RNA binding transcription antitermination factor activity |
IDA: Inferred from Direct Assay |
F |
complete | ||||
| GO:0003676 |
nucleic acid binding |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0003676 |
nucleic acid binding |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0003677 |
DNA binding |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0003677 |
DNA binding |
GOA:spkw |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0005737 |
cytoplasm |
GOA:spkw |
IEA: Inferred from Electronic Annotation |
C |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0005737 |
cytoplasm |
IEA: Inferred from Electronic Annotation |
SP_SL:SL-0086 |
C |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0006350 |
transcription |
GOA:spkw |
IEA: Inferred from Electronic Annotation |
P |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0006355 |
regulation of transcription, DNA-dependent |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
P |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0016020 |
membrane |
IDA: Inferred from Direct Assay |
C |
Seeded from EcoCyc (v14.0) |
complete | |||
| GO:0060567 |
negative regulation of transcription termination |
IDA: Inferred from Direct Assay |
P |
complete | ||||
| GO:0003723 |
RNA binding |
IDA: Inferred from Direct Assay |
F |
Figure 2 |
complete | |||
| GO:0003697 |
single-stranded DNA binding |
IDA: Inferred from Direct Assay |
F |
Figure 4 |
complete | |||
| edit table |
Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.
| Partner Type | Partner | Notes | References | Evidence |
|---|---|---|---|---|
|
Protein |
accA |
Experiment(s):EBI-879643, EBI-883980 | ||
|
Protein |
aidB |
Experiment(s):EBI-879643, EBI-883980 | ||
|
Protein |
deaD |
Experiment(s):EBI-879643, EBI-881486, EBI-883980 | ||
|
Protein |
hrpA |
Experiment(s):EBI-879643 | ||
|
Protein |
pnp |
Experiment(s):EBI-879643 | ||
|
Protein |
rho |
Experiment(s):EBI-879643, EBI-883980 | ||
|
Protein |
rplA |
Experiment(s):EBI-879643, EBI-883980 | ||
|
Protein |
rplB |
Experiment(s):EBI-879643, EBI-883980 | ||
|
Protein |
rplC |
Experiment(s):EBI-879643, EBI-883980 | ||
|
Protein |
rplE |
Experiment(s):EBI-879643, EBI-883980 | ||
|
Protein |
rplM |
Experiment(s):EBI-879643, EBI-883980 | ||
|
Protein |
rpsA |
Experiment(s):EBI-879643, EBI-883980 | ||
|
Protein |
rpsB |
Experiment(s):EBI-879643, EBI-883980 | ||
|
Protein |
rpsD |
Experiment(s):EBI-879643, EBI-883980 | ||
|
Protein |
rpsE |
Experiment(s):EBI-879643, EBI-883980 | ||
|
Protein |
rpsG |
Experiment(s):EBI-879643, EBI-883980 | ||
|
Protein |
rpsM |
Experiment(s):EBI-879643 | ||
|
Protein |
rnr |
Experiment(s):EBI-879643 | ||
|
Protein |
ycbY |
Experiment(s):EBI-879643 | ||
|
Protein |
rluC |
Experiment(s):EBI-879643 | ||
|
Protein |
rluB |
Experiment(s):EBI-879643 | ||
|
Protein |
yfiF |
Experiment(s):EBI-879643 | ||
|
Protein |
yhiR |
Experiment(s):EBI-879643, EBI-883980 | ||
|
Protein |
rplD |
Experiment(s):EBI-883980 | ||
|
Protein |
rplI |
Experiment(s):EBI-883980 | ||
|
Protein |
rplR |
Experiment(s):EBI-883980 | ||
|
Protein |
rplS |
Experiment(s):EBI-883980 | ||
|
Protein |
rplU |
Experiment(s):EBI-883980 | ||
|
Protein |
rplV |
Experiment(s):EBI-883980 | ||
|
Protein |
rplW |
Experiment(s):EBI-883980 | ||
|
Protein |
rplX |
Experiment(s):EBI-883980 | ||
|
Protein |
rpsC |
Experiment(s):EBI-883980 | ||
|
Protein |
rpsF |
Experiment(s):EBI-883980 | ||
|
Protein |
rpsI |
Experiment(s):EBI-883980 | ||
|
Protein |
rpsJ |
Experiment(s):EBI-883980 | ||
|
Protein |
rpsN |
Experiment(s):EBI-883980 | ||
|
Protein |
rpsT |
Experiment(s):EBI-883980 | ||
|
Protein |
rsmB |
Experiment(s):EBI-883980 | ||
|
Protein |
gmr |
Experiment(s):EBI-883980 | ||
|
Protein |
ydaY |
Experiment(s):EBI-883980 | ||
|
Protein |
yhbY |
Experiment(s):EBI-883980 | ||
|
Protein |
yhiP |
Experiment(s):EBI-883980 | ||
|
Protein |
yjdB |
Experiment(s):EBI-883980 | ||
|
Protein |
rluE |
Experiment(s):EBI-883980 | ||
|
Protein |
accD |
Experiment(s):EBI-883980 | ||
|
Protein |
yeeJ |
Experiment(s):EBI-883980 | ||
|
Protein |
creC |
Experiment(s):EBI-883980 | ||
|
Protein |
cspE |
Experiment(s):EBI-883980 | ||
|
Protein |
dnaJ |
Experiment(s):EBI-883980 | ||
|
Protein |
entB |
Experiment(s):EBI-883980 | ||
|
Protein |
glpK |
Experiment(s):EBI-883980 | ||
|
Protein |
hupA |
Experiment(s):EBI-883980 | ||
|
Protein |
hupB |
Experiment(s):EBI-883980 | ||
|
Protein |
metR |
Experiment(s):EBI-883980 | ||
|
Protein |
prpD |
Experiment(s):EBI-883980 | ||
|
Protein |
putA |
Experiment(s):EBI-883980 | ||
|
Protein |
rcsB |
Experiment(s):EBI-883980 | ||
|
Protein |
recN |
Experiment(s):EBI-883980 | ||
|
Protein |
rfaJ |
Experiment(s):EBI-883980 | ||
|
Protein |
rhlE |
Experiment(s):EBI-883980 | ||
|
Protein |
topA |
Experiment(s):EBI-1140933 | ||
|
Protein |
uspG |
Experiment(s):EBI-1140933 | ||
|
Protein |
rpsG |
Experiment(s):EBI-1140933 | ||
|
Protein |
rpsM |
Experiment(s):EBI-1140933 | ||
|
Protein |
rplA |
Experiment(s):EBI-1140933 | ||
|
Protein |
rplB |
Experiment(s):EBI-1140933 | ||
|
Protein |
cpxR |
Experiment(s):EBI-1140933 | ||
|
Protein |
rplD |
Experiment(s):EBI-1140933 | ||
|
Protein |
rpsD |
Experiment(s):EBI-1140933 | ||
|
Protein |
nadE |
Experiment(s):EBI-1140933 | ||
|
Protein |
ycgE |
Experiment(s):EBI-1140933 | ||
|
Protein |
rpsC |
Experiment(s):EBI-1140933 | ||
|
Protein |
accD |
LCMS(ID Probability):99.0 MALDI(Z-score):3.000505 | ||
|
Protein |
dnaJ |
LCMS(ID Probability):99.0 MALDI(Z-score):10.363976 | ||
|
Protein |
rpsT |
LCMS(ID Probability):99.6 | ||
|
Protein |
hupB |
LCMS(ID Probability):99.0 | ||
|
Protein |
rpsJ |
LCMS(ID Probability):99.6 MALDI(Z-score):3.290188 | ||
|
Protein |
rplS |
LCMS(ID Probability):99.0 MALDI(Z-score):4.815931 | ||
|
Protein |
rho |
LCMS(ID Probability):99.0 MALDI(Z-score):39.189659 | ||
|
Protein |
rplI |
LCMS(ID Probability):99.6 MALDI(Z-score):8.825591 | ||
|
Protein |
rpsN |
LCMS(ID Probability):99.6 | ||
|
Protein |
rpsM |
LCMS(ID Probability):80.0 MALDI(Z-score):18.672179 | ||
|
Protein |
rplX |
LCMS(ID Probability):99.6 | ||
|
Protein |
rpsF |
LCMS(ID Probability):99.0 | ||
|
Protein |
rpsA |
LCMS(ID Probability):99.6 MALDI(Z-score):27.294551 | ||
|
Protein |
rplM |
LCMS(ID Probability):99.6 MALDI(Z-score):3.999468 | ||
|
Protein |
rpsC |
LCMS(ID Probability):99.0 MALDI(Z-score):24.294405 | ||
|
Protein |
hupA |
LCMS(ID Probability):99.0 | ||
|
Protein |
rpsD |
LCMS(ID Probability):99.0 MALDI(Z-score):36.483049 | ||
|
Protein |
clpA |
MALDI(Z-score):18.860804 | ||
|
Protein |
rplB |
LCMS(ID Probability):99.0 MALDI(Z-score):31.855298 | ||
|
Protein |
rplE |
LCMS(ID Probability):99.0 MALDI(Z-score):8.291252 | ||
|
Protein |
rplW |
LCMS(ID Probability):99.6 | ||
|
Protein |
accA |
LCMS(ID Probability):99.0 MALDI(Z-score):31.439125 | ||
|
Protein |
rplA |
LCMS(ID Probability):99.0 MALDI(Z-score):31.854353 | ||
|
Protein |
rplR |
LCMS(ID Probability):99.6 | ||
|
Protein |
rplD |
LCMS(ID Probability):99.0 MALDI(Z-score):4.275541 | ||
|
Protein |
rlmL |
MALDI(Z-score):26.179233 | ||
|
Protein |
yfiF |
MALDI(Z-score):36.427608 | ||
|
Protein |
aidB |
LCMS(ID Probability):99.0 MALDI(Z-score):24.911783 | ||
|
Protein |
rnr |
MALDI(Z-score):24.701159 | ||
|
Protein |
recN |
LCMS(ID Probability):99.4 | ||
|
Protein |
rluB |
LCMS(ID Probability):90.0 MALDI(Z-score):37.004990 | ||
|
Protein |
pnp |
MALDI(Z-score):23.617200 | ||
|
Protein |
hfq |
LCMS(ID Probability):99.6 | ||
|
Protein |
yhiR |
LCMS(ID Probability):99.0 MALDI(Z-score):38.827197 | ||
|
Protein |
hrpA |
MALDI(Z-score):18.552100 | ||
|
Protein |
rluC |
LCMS(ID Probability):90.0 MALDI(Z-score):34.129450 | ||
|
Protein |
cspE |
LCMS(ID Probability):99.0 | ||
|
Protein |
ybjX |
MALDI(Z-score):21.166940 | ||
|
Protein |
rhlE |
LCMS(ID Probability):99.0 MALDI(Z-score):9.883347 | ||
| edit table |
</protect>
Notes
selective RNA binding sequence
AGGGAGGGA
PMID: 10476034
Figure 1
Localization
See Help:Product_localization for how to add or edit information in this section of EcoliWiki.
| Compartment | Description | Evidence | Reference/Source | Notes |
|---|---|---|---|---|
| edit table |
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Notes
Structure and Physical Properties
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Physical Properties
See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.
| Name | |
|---|---|
| Sequence |
MAKIKGQVKW FNESKGFGFI TPADGSKDVF VHFSAIQGNG FKTLAEGQNV EFEIQDGQKG PAAVNVTAI |
| Length |
69 |
| Mol. Wt |
7.401 kDa |
| pI |
7.3 (calculated) |
| Extinction coefficient |
5,500 (calc based on 0 Y, 1 W, and 0 C residues) |
| edit table |
Domains/Motifs/Modification Sites
|
See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.
|
<motif_map/> |
|
Structure
| </protect>
Structure figures<protect> | ||||||
Notes
Gene Product Resources
See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.
| Resource type | Source | Notes/Reference |
|---|---|---|
| edit table |
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Notes
Accessions in Other Databases
See Help:Gene_accessions for help with entering information into the Gene Accessions table.
| Database | Accession | Notes |
|---|---|---|
|
Escherichia coli str. K-12 substr. MG1655 | ||
|
Escherichia coli str. K-12 substr. MG1655 | ||
|
Escherichia coli str. K-12 substr. MG1655 | ||
|
Escherichia coli str. K-12 substr. MG1655 | ||
|
Escherichia coli str. K-12 substr. MG1655 | ||
|
Escherichia coli str. K-12 substr. MG1655 | ||
|
Escherichia coli str. K-12 substr. MG1655 | ||
|
Escherichia coli str. K-12 substr. MG1655 | ||
|
Escherichia coli str. K-12 substr. MG1655 | ||
| edit table |
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Notes
Links
| Name | URL | Comments |
|---|---|---|
| edit table |
References
See Help:References for how to manage references in EcoliWiki.
- ↑ 1.0 1.1 1.2 1.3 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
- ↑ 2.0 2.1 2.2 2.3 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
- ↑ 5.0 5.1 Bae, W et al. (2000) Escherichia coli CspA-family RNA chaperones are transcription antiterminators. Proc. Natl. Acad. Sci. U.S.A. 97 7784-9 PubMed
- ↑ Lasserre, JP et al. (2006) A complexomic study of Escherichia coli using two-dimensional blue native/SDS polyacrylamide gel electrophoresis. Electrophoresis 27 3306-21 PubMed
- ↑ 7.0 7.1 Phadtare, S & Inouye, M (1999) Sequence-selective interactions with RNA by CspB, CspC and CspE, members of the CspA family of Escherichia coli. Mol. Microbiol. 33 1004-14 PubMed
- ↑ 8.00 8.01 8.02 8.03 8.04 8.05 8.06 8.07 8.08 8.09 8.10 8.11 8.12 8.13 8.14 8.15 8.16 8.17 8.18 8.19 8.20 8.21 8.22 8.23 8.24 8.25 8.26 8.27 8.28 8.29 8.30 8.31 8.32 8.33 8.34 8.35 8.36 8.37 8.38 8.39 8.40 8.41 8.42 8.43 8.44 8.45 8.46 8.47 8.48 8.49 8.50 8.51 8.52 8.53 8.54 8.55 8.56 8.57 8.58 8.59 Butland, G et al. (2005) Interaction network containing conserved and essential protein complexes in Escherichia coli. Nature 433 531-7 PubMed
- ↑ 9.00 9.01 9.02 9.03 9.04 9.05 9.06 9.07 9.08 9.09 9.10 9.11 Arifuzzaman, M et al. (2006) Large-scale identification of protein-protein interaction of Escherichia coli K-12. Genome Res. 16 686-91 PubMed
- ↑ 10.00 10.01 10.02 10.03 10.04 10.05 10.06 10.07 10.08 10.09 10.10 10.11 10.12 10.13 10.14 10.15 10.16 10.17 10.18 10.19 10.20 10.21 10.22 10.23 10.24 10.25 10.26 10.27 10.28 10.29 10.30 10.31 10.32 10.33 10.34 10.35 10.36 10.37 10.38 Hu, P et al. (2009) Global functional atlas of Escherichia coli encompassing previously uncharacterized proteins. PLoS Biol. 7 e96 PubMed
- ↑ Finn, RD et al. (2010) The Pfam protein families database. Nucleic Acids Res. 38 D211-22 PubMed
Categories
- GO:0001072 ! transcription antitermination factor activity, RNA binding
- GO:0003676 ! nucleic acid binding
- GO:0003677 ! DNA binding
- GO:0005737 ! cytoplasm
- GO:0006350 ! transcription
- GO:0006355 ! regulation of transcription, DNA-templated
- GO:0016020 ! membrane
- GO:0060567 ! negative regulation of DNA-templated transcription, termination
- GO:0003723 ! RNA binding
- GO:0003697 ! single-stranded DNA binding
- Proteins
- RefGenome Annotated Gene
