cheW:Gene Product(s)

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Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.

Standard name

CheW

Synonyms

purine-binding chemotaxis protein[1], B1887[2][1], CheW[2][1] , ECK1888, JW1876, b1887

Product description

CheW[2][3]

Chemotaxis signal transducer; bridges CheA to chemoreceptors to regulate phophotransfer to CheY and CheB[4]

EC number (for enzymes)


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Notes

Function

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<protect> Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0004871

signal transducer activity

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR002545

F

Seeded from EcoCyc (v14.0)

complete

GO:0005622

intracellular

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR002545

C

Seeded from EcoCyc (v14.0)

complete

GO:0005737

cytoplasm

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0963

C

Seeded from EcoCyc (v14.0)

complete

GO:0005737

cytoplasm

GO_REF:0000023

IEA: Inferred from Electronic Annotation

SP_SL:SL-0086

C

Seeded from EcoCyc (v14.0)

complete

GO:0006935

chemotaxis

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR002545

P

Seeded from EcoCyc (v14.0)

complete

GO:0006935

chemotaxis

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0145

P

Seeded from EcoCyc (v14.0)

complete

GO:0007165

signal transduction

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR002545

P

Seeded from EcoCyc (v14.0)

complete

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Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type Partner Notes References Evidence

Protein

dadA

PMID:16606699[5]

Experiment(s):EBI-1141189

Protein

leuA

PMID:16606699[5]

Experiment(s):EBI-1141189

Protein

tsr

PMID:16606699[5]

Experiment(s):EBI-1141189

Protein

torA

PMID:16606699[5]

Experiment(s):EBI-1141189

Protein

yciA

PMID:16606699[5]

Experiment(s):EBI-1141189

Protein

yfjJ

PMID:16606699[5]

Experiment(s):EBI-1141189

Protein

atpD

PMID:16606699[5]

Experiment(s):EBI-1141189

Protein

hflK

PMID:16606699[5]

Experiment(s):EBI-1141189

Protein

rpsB

PMID:16606699[5]

Experiment(s):EBI-1141189

Protein

adk

PMID:16606699[5]

Experiment(s):EBI-1141189

Protein

rplN

PMID:16606699[5]

Experiment(s):EBI-1141189

Protein

bglX

PMID:16606699[5]

Experiment(s):EBI-1141189

Protein

dnaJ

PMID:16606699[5]

Experiment(s):EBI-1141189

Protein

clpX

PMID:16606699[5]

Experiment(s):EBI-1141189

Protein

minD

PMID:16606699[5]

Experiment(s):EBI-1141189

Protein

diaA

PMID:16606699[5]

Experiment(s):EBI-1141189

Protein

insC1

PMID:16606699[5]

Experiment(s):EBI-1141189

Protein

nadE

PMID:16606699[5]

Experiment(s):EBI-1141189

Protein

ftsZ

PMID:16606699[5]

Experiment(s):EBI-1141189

Protein

recA

PMID:16606699[5]

Experiment(s):EBI-1141189

Protein

yfcF

PMID:16606699[5]

Experiment(s):EBI-1141189

Protein

tar

PMID:16606699[5]

Experiment(s):EBI-1141189

Protein

dacA

PMID:16606699[5]

Experiment(s):EBI-1141189

Protein

mreB

PMID:16606699[5]

Experiment(s):EBI-1141189

Protein

yhgF

PMID:16606699[5]

Experiment(s):EBI-1141189

Protein

parE

PMID:19402753[6]

MALDI(Z-score):24.795104

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Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

Compartment Description Evidence Reference/Source Notes

cytoplasm

From EcoCyc[3]


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Notes

Structure and Physical Properties

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<protect> Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Name
Sequence

at EcoCyc 

MTGMTNVTKL ASEPSGQEFL VFTLGDEEYG IDILKVQEIR GYDQVTRIAN TPAFIKGVTN
LRGVIVPIVD LRIKFSQVDV DYNDNTVVIV LNLGQRVVGI VVDGVSDVLS LTAEQIRPAP
EFAVTLSTEY LTGLGALGDR MLILVNIEKL LNSEEMALLD SAASEVA
Length

167

Mol. Wt

18.083 kDa

pI

4.2 (calculated)

Extinction coefficient

5,960 (calc based on 4 Y, 0 W, and 0 C residues)

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Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Type Residues Description Notes References

Domain

18..155

PF01584 CheW-like domain

PMID:19920124[7]

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Structure
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

<beststructure> gene=cheW taxon=562,83333 </beststructure>

Models

View models at:

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Structure figures

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Notes

Gene Product Resources

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See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type Source Notes/Reference
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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

NCBI (Protein) (EcoliWiki Page)

GI:16129839

Escherichia coli str. K-12 substr. MG1655

NCBI (Protein) (EcoliWiki Page)

GeneID:946400

Escherichia coli str. K-12 substr. MG1655

ASAP

ASAP:ABE-0006292

Escherichia coli str. K-12 substr. MG1655

UniProt (EcoliWiki Page)

UniProtKB/Swiss-Prot:P0A964

Escherichia coli str. K-12 substr. MG1655

EcoCyc

EcoCyc:EG10149

Escherichia coli str. K-12 substr. MG1655

EcoGene

EcoGene:EG10149

Escherichia coli str. K-12 substr. MG1655

NCBI (Gene) (EcoliWiki Page)

GeneID:946400

Escherichia coli str. K-12 substr. MG1655

RegulonDB

RegulonDB:ECK120000145

Escherichia coli str. K-12 substr. MG1655

EchoBASE

EchoBASE:EB0147

Escherichia coli str. K-12 substr. MG1655

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Notes

Links

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References

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See Help:References for how to manage references in EcoliWiki.

  1. ↑ 1.0 1.1 1.2 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  5. ↑ 5.00 5.01 5.02 5.03 5.04 5.05 5.06 5.07 5.08 5.09 5.10 5.11 5.12 5.13 5.14 5.15 5.16 5.17 5.18 5.19 5.20 5.21 5.22 5.23 5.24 Arifuzzaman, M et al. (2006) Large-scale identification of protein-protein interaction of Escherichia coli K-12. Genome Res. 16 686-91 PubMed
  6. ↑ Hu, P et al. (2009) Global functional atlas of Escherichia coli encompassing previously uncharacterized proteins. PLoS Biol. 7 e96 PubMed
  7. ↑ Finn, RD et al. (2010) The Pfam protein families database. Nucleic Acids Res. 38 D211-22 PubMed

Categories

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