bolA:Gene Product(s)

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Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.

Standard name

BolA

Synonyms

regulator of penicillin binding proteins and beta lactamase transcription (morphogene)[1], B0435[2][1], BolA[2][1] , ECK0429, JW5060, b0435

Product description

BolA transcriptional regulator[2]; BolA transcriptional dual regulator[3]

Transcriptional repressor for mreB, morphogene; shape determinant; overexpression produces osmotically stable spherical cells; FtsZ dependent; induced by AI-2 pheromone[4]

EC number (for enzymes)


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Notes

Function

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<protect> Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0003677

DNA binding

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0238

F

Seeded from EcoCyc (v14.0)

complete

GO:0006350

transcription

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0804

P

Seeded from EcoCyc (v14.0)

complete

Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type Partner Notes References Evidence

Protein

grxD

PMID:15690043[5]

Experiment(s):EBI-889216, EBI-893481

Protein

yleA

PMID:15690043[5]

Experiment(s):EBI-889216

Protein

dppB

PMID:15690043[5]

Experiment(s):EBI-894289

Protein

yehY

PMID:15690043[5]

Experiment(s):EBI-894289

Protein

miaB

PMID:19402753[6]

MALDI(Z-score):24.026932

Protein

dppB

PMID:19402753[6]

LCMS(ID Probability):99.0

Protein

yehY

PMID:19402753[6]

LCMS(ID Probability):99.0

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Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

Compartment Description Evidence Reference/Source Notes

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Notes

Structure and Physical Properties

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<protect> Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Name
Sequence

at EcoCyc

MTSQRCRRRY FMMIRERIEE KLRAAFQPVF LEVVDESYRH NVPAGSESHF KVVLVSDRFT
GERFLNRHRM IYSTLAEELS TTVHALALHT YTIKEWEGLQ DTVFASPPCR GAGSIA
Length

116

Mol. Wt

13.478 kDa

pI

8.7 (calculated)

Extinction coefficient

11,460 - 11,710 (calc based on 4 Y, 1 W, and 2 C residues)


Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Type Residues Description Notes References

Domain

9..85

PF01722 BolA-like protein

PMID:19920124[7]

<motif_map/>

Structure
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

<beststructure> gene=bolA taxon=562,83333 </beststructure>

Models

View models at:

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Structure figures

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Notes

Gene Product Resources

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See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type Source Notes/Reference

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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

NCBI (Protein) (EcoliWiki Page)

GI:90111135

Escherichia coli str. K-12 substr. MG1655

NCBI (Protein) (EcoliWiki Page)

GeneID:947043

Escherichia coli str. K-12 substr. MG1655

ASAP

ASAP:ABE-0001508

Escherichia coli str. K-12 substr. MG1655

UniProt (EcoliWiki Page)

UniProtKB/Swiss-Prot:P0ABE2

Escherichia coli str. K-12 substr. MG1655

EcoCyc

EcoCyc:EG10125

Escherichia coli str. K-12 substr. MG1655

EcoGene

EcoGene:EG10125

Escherichia coli str. K-12 substr. MG1655

NCBI (Gene) (EcoliWiki Page)

GeneID:947043

Escherichia coli str. K-12 substr. MG1655

RegulonDB

RegulonDB:ECK120000121

Escherichia coli str. K-12 substr. MG1655

EchoBASE

EchoBASE:EB0123

Escherichia coli str. K-12 substr. MG1655

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Notes

Links

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References

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See Help:References for how to manage references in EcoliWiki.

  1. 1.0 1.1 1.2 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 2.2 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  5. 5.0 5.1 5.2 5.3 Butland, G et al. (2005) Interaction network containing conserved and essential protein complexes in Escherichia coli. Nature 433 531-7 PubMed
  6. 6.0 6.1 6.2 Hu, P et al. (2009) Global functional atlas of Escherichia coli encompassing previously uncharacterized proteins. PLoS Biol. 7 e96 PubMed
  7. Finn, RD et al. (2010) The Pfam protein families database. Nucleic Acids Res. 38 D211-22 PubMed

Categories

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