atpA:Gene Product(s)
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| Nomenclature | Function | Interactions | Localization | Sequence | Domains | Structure | Resources | Accessions | Links | References | Suggestions |
Nomenclature
See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.
| Standard name |
AtpA |
|---|---|
| Synonyms |
F1 sector of membrane-bound ATP synthase, alpha subunit[1], B3734[2][1], Unc[2][1], UncA[2][1], PapA[2][1], AtpA[2][1] , ECK3727, JW3712, papA, uncA, b3734 |
| Product description |
ATP synthase, F1 complex, α subunit[2][3]; Component of α subunit complex[2][3]; ATP synthase, F1 complex[2][3]; ATP synthase[2][3] ATP synthase subunit alpha, membrane-bound, F1 sector[4] |
| EC number (for enzymes) | |
| edit table |
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Notes
Function
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Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0015986 |
ATP synthesis coupled proton transport |
IMP: Inferred from Mutant Phenotype |
P |
complete | ||||
| GO:0000166 |
nucleotide binding |
GOA:spkw |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0045261 |
proton-transporting ATP synthase complex, catalytic core F(1) |
IMP: Inferred from Mutant Phenotype |
C |
Component of F1 ATP synthase with gene products of uncD (beta subunit), uncG (gamma subunit), uncH (delta subunit) and uncC (epsilon subunit) - for a review, see Chapter 19 of Escherichia coli and Salmonella: Cellular and Molecular Biology, 2nd Edition. |
complete | |||
| GO:0005524 |
ATP binding |
GOA:hamap |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
|
Contributes to |
GO:0046961 |
proton-transporting ATPase activity, rotational mechanism |
IDA: Inferred from Direct Assay |
F |
complete | |||
| GO:0005524 |
ATP binding |
GOA:spkw |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0005886 |
plasma membrane |
GOA:spkw |
IEA: Inferred from Electronic Annotation |
C |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0005886 |
plasma membrane |
GOA:spkw |
IEA: Inferred from Electronic Annotation |
C |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0015986 |
ATP synthesis coupled proton transport |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
P |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0015986 |
ATP synthesis coupled proton transport |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
P |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0015986 |
ATP synthesis coupled proton transport |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
P |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0015986 |
ATP synthesis coupled proton transport |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
P |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0015986 |
ATP synthesis coupled proton transport |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
P |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0016020 |
membrane |
IDA: Inferred from Direct Assay |
C |
Seeded from EcoCyc (v14.0) |
complete | |||
| GO:0016787 |
hydrolase activity |
GOA:spkw |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0016820 |
hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0016820 |
hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0016820 |
hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0019898 |
extrinsic to membrane |
IEA: Inferred from Electronic Annotation |
SP_SL:SL-9903 |
C |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0042777 |
plasma membrane ATP synthesis coupled proton transport |
GOA:hamap |
IEA: Inferred from Electronic Annotation |
P |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0045261 |
proton-transporting ATP synthase complex, catalytic core F(1) |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
C |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0045261 |
proton-transporting ATP synthase complex, catalytic core F(1) |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
C |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0045261 |
proton-transporting ATP synthase complex, catalytic core F(1) |
GOA:spkw |
IEA: Inferred from Electronic Annotation |
C |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0046933 |
hydrogen ion transporting ATP synthase activity, rotational mechanism |
GOA:hamap |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0046933 |
hydrogen ion transporting ATP synthase activity, rotational mechanism |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0046933 |
hydrogen ion transporting ATP synthase activity, rotational mechanism |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0046933 |
hydrogen ion transporting ATP synthase activity, rotational mechanism |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0046961 |
proton-transporting ATPase activity, rotational mechanism |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0046961 |
proton-transporting ATPase activity, rotational mechanism |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0046961 |
proton-transporting ATPase activity, rotational mechanism |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
| edit table |
Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.
| Partner Type | Partner | Notes | References | Evidence |
|---|---|---|---|---|
|
Protein |
Subunits of α subunit complex |
could be indirect |
||
|
Protein |
atpD |
Experiment(s):EBI-878836 | ||
|
Protein |
rmlA1 |
Experiment(s):EBI-1146615 | ||
|
Protein |
pepB |
Experiment(s):EBI-1146615 | ||
|
Protein |
glmU |
Experiment(s):EBI-1146615 | ||
|
Protein |
parE |
MALDI(Z-score):24.616976 | ||
|
Protein |
topA |
MALDI(Z-score):25.391048 | ||
|
Protein |
topB |
MALDI(Z-score):28.777663 | ||
|
Protein |
atpD |
MALDI(Z-score):17.053160 | ||
|
Protein |
Subunits of ATP synthase, F1 complex |
could be indirect |
||
|
Protein |
Subunits of ATP synthase |
could be indirect |
| |
| edit table |
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Notes
Localization
See Help:Product_localization for how to add or edit information in this section of EcoliWiki.
| Compartment | Description | Evidence | Reference/Source | Notes |
|---|---|---|---|---|
|
plasma membrane |
From EcoCyc[3] |
|||
|
Cytoplasm |
| |||
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Notes
Structure and Physical Properties
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Physical Properties
See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.
| Name | |
|---|---|
| Sequence |
MQLNSTEISE LIKQRIAQFN VVSEAHNEGT IVSVSDGVIR IHGLADCMQG EMISLPGNRY AIALNLERDS VGAVVMGPYA DLAEGMKVKC TGRILEVPVG RGLLGRVVNT LGAPIDGKGP LDHDGFSAVE AIAPGVIERQ SVDQPVQTGY KAVDSMIPIG RGQRELIIGD RQTGKTALAI DAIINQRDSG IKCIYVAIGQ KASTISNVVR KLEEHGALAN TIVVVATASE SAALQYLAPY AGCAMGEYFR DRGEDALIIY DDLSKQAVAY RQISLLLRRP PGREAFPGDV FYLHSRLLER AARVNAEYVE AFTKGEVKGK TGSLTALPII ETQAGDVSAF VPTNVISITD GQIFLETNLF NAGIRPAVNP GISVSRVGGA AQTKIMKKLS GGIRTALAQY RELAAFSQFA SDLDDATRKQ LDHGQKVTEL LKQKQYAPMS VAQQSLVLFA AERGYLADVE LSKIGSFEAA LLAYVDRDHA PLMQEINQTG GYNDEIEGKL KGILDSFKAT QSW |
| Length |
513 |
| Mol. Wt |
55.222 kDa |
| pI |
6.0 (calculated) |
| Extinction coefficient |
29,340 - 29,840 (calc based on 16 Y, 1 W, and 4 C residues) |
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Domains/Motifs/Modification Sites
|
See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.
|
<motif_map/> |
|
Structure
| </protect>
Structure figures<protect> | ||||||
Notes
Gene Product Resources
See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.
| Resource type | Source | Notes/Reference |
|---|---|---|
| edit table |
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Notes
Accessions in Other Databases
See Help:Gene_accessions for help with entering information into the Gene Accessions table.
| Database | Accession | Notes |
|---|---|---|
|
Escherichia coli str. K-12 substr. MG1655 | ||
|
Escherichia coli str. K-12 substr. MG1655 | ||
|
Escherichia coli str. K-12 substr. MG1655 | ||
|
Escherichia coli str. K-12 substr. MG1655 | ||
|
Escherichia coli str. K-12 substr. MG1655 | ||
|
Escherichia coli str. K-12 substr. MG1655 | ||
|
Escherichia coli str. K-12 substr. MG1655 | ||
|
Escherichia coli str. K-12 substr. MG1655 | ||
|
Escherichia coli str. K-12 substr. MG1655 | ||
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Notes
Links
| Name | URL | Comments |
|---|---|---|
| edit table |
References
See Help:References for how to manage references in EcoliWiki.
- ↑ 1.0 1.1 1.2 1.3 1.4 1.5 1.6 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
- ↑ 2.0 2.1 2.2 2.3 2.4 2.5 2.6 2.7 2.8 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ 3.0 3.1 3.2 3.3 3.4 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
- ↑ Butlin, JD et al. (1971) Oxidative phosphorylation in Escherichia coli K12. Mutations affecting magnesium ion- or calcium ion-stimulated adenosine triphosphatase. Biochem. J. 124 75-81 PubMed
- ↑ Kanazawa, H et al. (1978) Coupling factor ATPase from Escherichia coli. An uncA mutant (uncA401) with defective alpha subunit. J. Biochem. 84 1513-7 PubMed
- ↑ Klionsky, DJ & Simoni, RD (1985) Assembly of a functional F1 of the proton-translocating ATPase of Escherichia coli. J. Biol. Chem. 260 11200-6 PubMed
- ↑ Lasserre, JP et al. (2006) A complexomic study of Escherichia coli using two-dimensional blue native/SDS polyacrylamide gel electrophoresis. Electrophoresis 27 3306-21 PubMed
- ↑ Butland, G et al. (2005) Interaction network containing conserved and essential protein complexes in Escherichia coli. Nature 433 531-7 PubMed
- ↑ 10.0 10.1 10.2 Arifuzzaman, M et al. (2006) Large-scale identification of protein-protein interaction of Escherichia coli K-12. Genome Res. 16 686-91 PubMed
- ↑ 11.0 11.1 11.2 11.3 Hu, P et al. (2009) Global functional atlas of Escherichia coli encompassing previously uncharacterized proteins. PLoS Biol. 7 e96 PubMed
- ↑ Link, AJ et al. (1997) Comparing the predicted and observed properties of proteins encoded in the genome of Escherichia coli K-12. Electrophoresis 18 1259-313 PubMed
- ↑ 13.0 13.1 13.2 Finn, RD et al. (2010) The Pfam protein families database. Nucleic Acids Res. 38 D211-22 PubMed
Categories
- GO:0015986 ! ATP synthesis coupled proton transport
- GO:0000166 ! nucleotide binding
- GO:0045261 ! proton-transporting ATP synthase complex, catalytic core F(1)
- GO:0005524 ! ATP binding
- GO:0046961 ! proton-transporting ATPase activity, rotational mechanism
- GO:0005886 ! plasma membrane
- GO:0016020 ! membrane
- GO:0016787 ! hydrolase activity
- GO:0016820 ! hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances
- GO:0019898 ! extrinsic component of membrane
- GO:0042777 ! plasma membrane ATP synthesis coupled proton transport
- GO:0046933 ! proton-transporting ATP synthase activity, rotational mechanism
- Proteins
- RefGenome Annotated Gene
