asnC:Gene Product(s)
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| Quickview | Gene | Gene Product(s) | Expression | Evolution | On One Page |
| Nomenclature | Function | Interactions | Localization | Sequence | Domains | Structure | Resources | Accessions | Links | References | Suggestions |
Nomenclature
See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.
| Standard name |
AsnC |
|---|---|
| Synonyms |
DNA-binding transcriptional dual regulator[1], B3743[2][1], AsnC[2][1] , ECK3737, JW3721, b3743 |
| Product description |
AsnC transcriptional repressor[2]; AsnC transcriptional dual regulator[3] Regulatory gene for asnA, asnC, gidA, Lrp family[4] |
| EC number (for enzymes) |
|
| edit table |
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Notes
Function
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Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0003700 |
transcription factor activity |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0003700 |
transcription factor activity |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0003700 |
transcription factor activity |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0003700 |
transcription factor activity |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0003700 |
transcription factor activity |
IDA: Inferred from Direct Assay |
F |
Seeded from EcoCyc (v14.0) |
complete | |||
| GO:0003700 |
transcription factor activity |
ISS: Inferred from Sequence or Structural Similarity |
F |
Seeded from EcoCyc (v14.0) |
complete | |||
| GO:0005622 |
intracellular |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
C |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0005622 |
intracellular |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
C |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0005622 |
intracellular |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
C |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0005622 |
intracellular |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
C |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0016563 |
transcription activator activity |
IDA: Inferred from Direct Assay |
F |
Seeded from EcoCyc (v14.0) |
complete | |||
| GO:0016563 |
transcription activator activity |
ISS: Inferred from Sequence or Structural Similarity |
F |
Seeded from EcoCyc (v14.0) |
complete | |||
| GO:0016566 |
specific transcriptional repressor activity |
IDA: Inferred from Direct Assay |
F |
Seeded from EcoCyc (v14.0) |
complete | |||
| GO:0016566 |
specific transcriptional repressor activity |
ISS: Inferred from Sequence or Structural Similarity |
F |
Seeded from EcoCyc (v14.0) |
complete | |||
| GO:0016597 |
amino acid binding |
IPI: Inferred from Physical Interaction |
KEGG_LIGAND:C00152 |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0032582 |
negative regulation of gene-specific transcription |
IDA: Inferred from Direct Assay |
P |
Seeded from EcoCyc (v14.0) |
complete | |||
| GO:0032582 |
negative regulation of gene-specific transcription |
ISS: Inferred from Sequence or Structural Similarity |
P |
Seeded from EcoCyc (v14.0) |
complete | |||
| GO:0043193 |
positive regulation of gene-specific transcription |
IDA: Inferred from Direct Assay |
P |
Seeded from EcoCyc (v14.0) |
complete | |||
| GO:0043193 |
positive regulation of gene-specific transcription |
ISS: Inferred from Sequence or Structural Similarity |
P |
Seeded from EcoCyc (v14.0) |
complete | |||
| GO:0043200 |
response to amino acid stimulus |
IDA: Inferred from Direct Assay |
P |
Seeded from EcoCyc (v14.0) |
complete | |||
| GO:0043565 |
sequence-specific DNA binding |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0043565 |
sequence-specific DNA binding |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0043565 |
sequence-specific DNA binding |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0043565 |
sequence-specific DNA binding |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0043565 |
sequence-specific DNA binding |
ISS: Inferred from Sequence or Structural Similarity |
F |
Seeded from EcoCyc (v14.0) |
complete | |||
| edit table |
Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.
| Partner Type | Partner | Notes | References | Evidence |
|---|---|---|---|---|
|
Protein |
hchA |
Experiment(s):EBI-1146629 | ||
|
Protein |
asnA |
asnC is a transcriptional activator of asnA |
| |
| edit table |
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Notes
Localization
See Help:Product_localization for how to add or edit information in this section of EcoliWiki.
| Compartment | Description | Evidence | Reference/Source | Notes |
|---|---|---|---|---|
| edit table |
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Notes
Structure and Physical Properties
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Physical Properties
See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.
| Name | |
|---|---|
| Sequence |
MENYLIDNLD RGILEALMGN ARTAYAELAK QFGVSPGTIH VRVEKMKQAG IITGARIDVS PKQLGYDVGC FIGIILKSAK DYPSALAKLE SLDEVTEAYY TTGHYSIFIK VMCRSIDALQ HVLINKIQTI DEIQSTETLI VLQNPIMRTI KP |
| Length |
152 |
| Mol. Wt |
16.888 kDa |
| pI |
6.7 (calculated) |
| Extinction coefficient |
10,430 - 10,680 (calc based on 7 Y, 0 W, and 2 C residues) |
| edit table |
Domains/Motifs/Modification Sites
|
See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.
|
<motif_map/> |
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Structure
| </protect>
Structure figures<protect> | ||||||
Notes
Gene Product Resources
See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.
| Resource type | Source | Notes/Reference |
|---|---|---|
| edit table |
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Notes
Accessions in Other Databases
See Help:Gene_accessions for help with entering information into the Gene Accessions table.
| Database | Accession | Notes |
|---|---|---|
|
Escherichia coli str. K-12 substr. MG1655 | ||
|
Escherichia coli str. K-12 substr. MG1655 | ||
|
Escherichia coli str. K-12 substr. MG1655 | ||
|
Escherichia coli str. K-12 substr. MG1655 | ||
|
Escherichia coli str. K-12 substr. MG1655 | ||
|
Escherichia coli str. K-12 substr. MG1655 | ||
|
Escherichia coli str. K-12 substr. MG1655 | ||
|
Escherichia coli str. K-12 substr. MG1655 | ||
|
Escherichia coli str. K-12 substr. MG1655 | ||
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Notes
Links
| Name | URL | Comments |
|---|---|---|
| edit table |
References
See Help:References for how to manage references in EcoliWiki.
- ↑ 1.0 1.1 1.2 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
- ↑ 2.0 2.1 2.2 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
- ↑ 5.00 5.01 5.02 5.03 5.04 5.05 5.06 5.07 5.08 5.09 5.10 5.11 Kölling, R & Lother, H (1985) AsnC: an autogenously regulated activator of asparagine synthetase A transcription in Escherichia coli. J. Bacteriol. 164 310-5 PubMed
- ↑ Thaw, P et al. (2006) Structural insight into gene transcriptional regulation and effector binding by the Lrp/AsnC family. Nucleic Acids Res. 34 1439-49 PubMed
- ↑ Arifuzzaman, M et al. (2006) Large-scale identification of protein-protein interaction of Escherichia coli K-12. Genome Res. 16 686-91 PubMed
- ↑ Kölling, R et al. (1988) AsnC, a multifunctional regulator of genes located around the replication origin of Escherichia coli, oriC. Mol. Gen. Genet. 212 99-104 PubMed
- ↑ 9.0 9.1 Finn, RD et al. (2010) The Pfam protein families database. Nucleic Acids Res. 38 D211-22 PubMed
Categories
- GO:0003700 ! DNA-binding transcription factor activity
- GO:0005622 ! intracellular
- GO:0016563 ! obsolete transcription activator activity
- GO:0016566 ! obsolete specific transcriptional repressor activity
- GO:0016597 ! amino acid binding
- GO:0032582 ! negative regulation of gene-specific transcription
- GO:0043193 ! positive regulation of gene-specific transcription
- GO:0043200 ! response to amino acid
- GO:0043565 ! sequence-specific DNA binding
- Proteins