acpT:Quickview

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions

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Standard Name

acpT

Gene Synonym(s)

ECK3459, b3475, JW3440, yhhU[1], yhhU

Product Desc.

holo-[acyl carrier protein] synthase 2[2][3]

CoA-phosphopantetheinyltransferase; native apo-protein substrate unknown, possibly a back-up gene for acpS; multicopy suppressor of acpS1, can modify ACP when overexpressed[4]

Product Synonyms(s)

holo-(acyl carrier protein) synthase 2[1], B3475[2][1], YhhU[2][1], AcpT[2][1] , ECK3459, JW3440, yhhU, b3475

Function from GO

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Knock-Out Phenotype
Regulation/Expression

transcription unit(s): acpT[2]

Regulation/Activity
Quick Links

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Notes

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A nonsense mutation making a truncated YejM causes increased outer membrane permeability,TS growth, and reduced of lipid A synthesis; these phenotypes, and the lethality of a null mutation, are suppressible by a multicopy acpT clone (Hirvas, 1997; De Lay, 2008).[4]



References

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  1. 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 2.2 2.3 2.4 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.