Phage phiX174 E:Gene Product(s)

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Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

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Standard name

E

Synonyms

phiX174p08 [1], gpE [1], protein E [1]

Product description

cell lysis protein [1]; cell lysis [1]

EC number (for enzymes)



Notes

Function

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Gene Ontology <protect> See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0019077

lytic viral release

PMID:19379010[2]

IDA: Inferred from Direct Assay

P

complete

GO:0005515

protein binding

PMID:19379010[2]

IPI: Inferred from Physical Interaction

EcoliWiki:mraY


F

complete

GO:0005887

integral to plasma membrane

PMID:19379010[2]

IDA: Inferred from Direct Assay

C

complete


Interactions

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Partner Type Partner Notes References Evidence


</protect>

Notes

Localization

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Compartment Description Evidence Reference/Source Notes



Notes

Structure and Physical Properties

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Physical Properties <protect> See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Name
Sequence
MVRWTLWDTL AFLLLLSLLL PSLLIMFIPS TFKRPVSSWK ALNLRKTLLM ASSVRLKPLN
CSRLPCVYAQ ETLTFLLTQK KTCVKNYVRK E
Length

91

Mol. Wt

10.602 kDa

pI

10.8 (calculated)

Extinction coefficient

19,480 - 19,855 (calc based on 2 Y, 3 W, and 3 C residues)


Domains/Motifs/Modification Sites

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Type Residues Description Notes References

Domain

10 - 32

Predicted membrane-spanning helix.

TMD predicted by TMHMM[3]


<motif_map/>

tmhmm.php?gene=Phage_phiX174_E&show=pic&.jpg
Click the image to view raw output from TMHMM.

Structure

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Structures

<beststructure> gene=Phage_phiX174_E taxon=10847 </beststructure>

Models

View models at:


</protect>

Structure figures

Notes

Gene Product Resources


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Resource type Source Notes/Reference


Notes

Accessions in Other Databases


See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes


Notes

Links





References


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  1. ↑ 1.0 1.1 1.2 1.3 1.4 NCBI: Enterobacteria phage phiX174, complete genome http://www.ncbi.nlm.nih.gov/nuccore/NC_001422
  2. ↑ 2.0 2.1 2.2 Zheng, Y et al. (2009) Purification and functional characterization of phiX174 lysis protein E. Biochemistry 48 4999-5006 PubMed
  3. ↑ Krogh, A et al. (2001) Predicting transmembrane protein topology with a hidden Markov model: application to complete genomes. J. Mol. Biol. 305 567-80 PubMed

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