Phage lambda R:Gene Product(s)

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Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

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Standard name

R

Synonyms

R, lambdap75

Product description

cell lysis protein (murein transglycosylase)

EC number (for enzymes)


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Notes

Function

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<protect> Gene Ontology See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0003796

lysozyme activity

PMID:14047209[1]

IMP: Inferred from Mutant Phenotype

F

Endolysin

complete

GO:0008933

lytic transglycosylase activity

PMID:6460914[2]

IDA: Inferred from Direct Assay

F

complete

GO:0005829

cytosol

PMID:6448076[3]

IDA: Inferred from Direct Assay

C

complete

GO:0051603

proteolysis involved in cellular protein catabolic process

PMID:6460914[2]

IDA: Inferred from Direct Assay

P

complete

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Interactions <protect> See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type Partner Notes References Evidence
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</protect>


Notes

Localization

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Compartment Description Evidence Reference/Source Notes
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Notes

Structure and Physical Properties

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<protect> Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Name
Sequence 
MVEINNQRKA FLDMLAWSEG TDNGRQKTRN HGYDVIVGGE LFTDYSDHPR KLVTLNPKLK
STGAGRYQLL SRWWDAYRKQ LGLKDFSPKS QDAVALQQIK ERGALPMIDR GDIRQAIDRC
SNIWASLPGA GYGQFEHKAD SLIAKFKEAG GTVREIDV
Length

158

Mol. Wt

17.825 kDa

pI

9.6 (calculated)

Extinction coefficient

29,450 - 29,575 (calc based on 5 Y, 4 W, and 1 C residues)

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Domains/Motifs/Modification Sites

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Type Residues Description Notes References
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<motif_map/>

Structure
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Structures

<beststructure> gene=Phage_lambda_R taxon=10710 </beststructure>

Models

View models at:

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</protect>

Structure figures

See Help:Jmol in EcoliWiki

1D9U.pdb:Lambda R with substrate analog
<jmol> <jmolApplet> <color>white</color> <uploadedFileContents >1D9U.pdb</uploadedFileContents> <name></name> <script> wireframe off; spacefill off; trace off; rotate ON; cartoon; color chain; select NAG; color yellow; spacefill on; </script> </jmolApplet> </jmol>
<jmol> <jmolCheckbox > <scriptWhenChecked > rotate on; </scriptWhenChecked > <scriptWhenUnchecked > rotate off; </scriptWhenUnchecked > <checked>true</checked> <text>rotate</text> </jmolCheckbox > <jmolButton><script>reset; </script><text>reset</text></jmolButton> </jmol>









<protect>

</protect>

Notes

Gene Product Resources

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See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type Source Notes/Reference
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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes
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Notes

Links

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Name URL Comments
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References

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  1. ↑ CAMPBELL, A & DELCAMPILLO-CAMPBELL, A (1963) MUTANT OF LAMBDA BACTERIOPHAGE PRODUCING A THERMOLABILE ENDOLYSIN. J. Bacteriol. 85 1202-7 PubMed
  2. ↑ 2.0 2.1 Bienkowska-Szewczyk, K et al. (1981) The R gene product of bacteriophage lambda is the murein transglycosylase. Mol. Gen. Genet. 184 111-4 PubMed
  3. ↑ Bieńkowska-Szewczyk, K & Taylor, A (1980) Murein transglycosylase from phage lambda lysate. Purification and properties. Biochim. Biophys. Acta 615 489-96 PubMed

Categories

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