alsE:Gene Product(s)

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Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.

Standard name

AlsE

Synonyms

allulose-6-phosphate 3-epimerase[1], B4085[2][1], YjcU product[2][1], AlsE[2][1]

Product description

EG11957[2][3]

Allulose-6-P 3-epimerase[4]

EC number (for enzymes)


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Notes

Function

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Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference(s) Evidence Code with/from Aspect Notes Status
GO:0004750

ribulose-phosphate 3-epimerase activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000056

F

Seeded from EcoCyc [5]

complete

GO:0005975

carbohydrate metabolic process

GO_REF:0000002
GO_REF:0000004

IEA: Inferred from Electronic Annotation

InterPro:IPR000056
SP_KW:KW-0119

P

Seeded from EcoCyc [5]

complete

GO:0003824

catalytic activity

GO_REF:0000002
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR011060
InterPro:IPR013785

F

Seeded from EcoCyc [5]

complete

GO:0008152

metabolic process

GO_REF:0000002
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR011060
InterPro:IPR013785

P

Seeded from EcoCyc [5]

complete

GO:0016853

isomerase activity

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0413

F

Seeded from EcoCyc [5]

complete

GO:0005515

protein binding

PMID:16606699[6]

IPI: Inferred from Physical Interaction

UniProtKB:P35340

F

Seeded from EcoCyc [5]

complete

GO:0016857

racemase and epimerase activity, acting on carbohydrates and derivatives

PMID:18700786[7]

IDA: Inferred from Direct Assay

F

Seeded from EcoCyc 12.5 [8]

complete

GO:0019316

D-allose catabolic process

PMID:10559180[9]

IMP: Inferred from Mutant Phenotype

P

Seeded from EcoCyc [5]

complete

GO:0034700

allulose 6-phosphate 3-epimerase activity

PMID:18700786[7]

IDA: Inferred from Direct Assay

F

Seeded from EcoCyc [5]

complete

GO:0019316

D-allose catabolic process

PMID:10559180[9]

IMP: Inferred from Mutant Phenotype

P

alsE insertion mutants can't grow on D-allose as the sole carbon source.

complete

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Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type Partner Notes References Evidence

Protein

ahpF

PMID:16606699[6]

Experiment(s):EBI-1147423

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Notes

Localization

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Compartment Description Evidence Notes
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Notes

Structure and Physical Properties

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Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Sequence

at EcoCyc

MKISPSLMCM DLLKFKEQIE FIDSHADYFH IDIMDGHFVP NLTLSPFFVS QVKKLATKPL
DCHLMVTRPQ DYIAQLARAG ADFITLHPET INGQAFRLID EIRRHDMKVG LILNPETPVE
AMKYYIHKAD KITVMTVDPG FAGQPFIPEM LDKLAELKAW REREGLEYEI EVDGSCNQAT
YEKLMAAGAD VFIVGTSGLF NHAENIDEAW RIMTAQILAA KSEVQPHAKT A
Length

231

Mol. Wt

26.109 kDa

pI

5.4 (calculated)

Extinction coefficient

19,940 - 20,315 (calc based on 6 Y, 2 W, and 3 C residues)

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Domains/Motifs/Modification Sites

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Type Residues Description Notes
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<motif_map/>

Structure
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

<beststructure> gene=alsE taxon=562,83333 </beststructure>

Models

View models at:

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Structure figures

Notes

Gene Product Resources

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See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type Source Notes/Reference
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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

EcoCyc (EcoliWiki Page)

EcoCyc:EG11957-MONOMER

UniProt (EcoliWiki Page)

UniProt:P32719

PFAM (EcoliWiki Page)

PFAM:PF00834

RefSeq (EcoliWiki Page)

RefSeq:NP_418509

ModBase (EcoliWiki Page)

ModBase:P32719


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Notes

Links

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Name URL Comments
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References

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See Help:References for how to manage references in EcoliWiki.

  1. ↑ 1.0 1.1 1.2 1.3 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  5. ↑ 5.0 5.1 5.2 5.3 5.4 5.5 5.6 5.7 EcoCyc (release 13.0; 2009) Keseler, IM et al. (2009) Nucleic Acids Res. 37(Database issue):D464-70
  6. ↑ 6.0 6.1 Arifuzzaman, M et al. (2006) Large-scale identification of protein-protein interaction of Escherichia coli K-12. Genome Res. 16 686-91 PubMed
  7. ↑ 7.0 7.1 Chan, KK et al. (2008) Structural basis for substrate specificity in phosphate binding (beta/alpha)8-barrels: D-allulose 6-phosphate 3-epimerase from Escherichia coli K-12. Biochemistry 47 9608-17 PubMed
  8. ↑ EcoCyc (release 12.5; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  9. ↑ 9.0 9.1 Poulsen, TS et al. (1999) D-Allose catabolism of Escherichia coli: involvement of alsI and regulation of als regulon expression by allose and ribose. J. Bacteriol. 181 7126-30 PubMed

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