atpH:Gene Product(s)

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.

Standard name

AtpH

Synonyms

F1 sector of membrane-bound ATP synthase, delta subunit[1], B3735[2][1], Unc[2][1], UncH[2][1], PapE[2][1], AtpH[2][1]

Product description

ATP synthase, F1 complex, δ subunit[2][3];

Component of ATP synthase, F1 complex[2][3]; ATP synthase[2][3]

ATP synthase subunit delta, membrane-bound, F1 sector[4]

EC number (for enzymes)
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Notes

Function

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Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference(s) Evidence Code with/from Aspect Notes Status
GO:0016020

membrane

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0472

C

Seeded from EcoCyc [5]

complete

GO:0006754

ATP biosynthetic process

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0066

P

Seeded from EcoCyc [5]

complete

GO:0006810

transport

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0813

P

Seeded from EcoCyc [5]

complete

GO:0006811

ion transport

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0406

P

Seeded from EcoCyc [5]

complete

GO:0015078

hydrogen ion transmembrane transporter activity

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0375

F

Seeded from EcoCyc [5]

complete

GO:0015986

ATP synthesis coupled proton transport

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000711

P

Seeded from EcoCyc 12.5 [6]

complete

GO:0015992

proton transport

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0375

P

Seeded from EcoCyc [5]

complete

GO:0046961

proton-transporting ATPase activity, rotational mechanism

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000711

F

Seeded from EcoCyc [5]

complete

GO:0016469

proton-transporting two-sector ATPase complex

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000711

C

Seeded from EcoCyc 12.5 [6]

complete

GO:0016787

hydrolase activity

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0378

F

Seeded from EcoCyc 12.5 [6]

complete

GO:0045261

proton-transporting ATP synthase complex, catalytic core F(1)

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0139

C

Seeded from EcoCyc 12.5 [6]

complete

GO:0046872

metal ion binding

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0066

F

Seeded from EcoCyc [5]

complete

GO:0046933

hydrogen ion transporting ATP synthase activity, rotational mechanism

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000711

F

Seeded from EcoCyc [5]

complete

GO:0005737

cytoplasm

C

Seeded from EcoCyc 11.1[3].

required fields missing

GO:0005886

plasma membrane

GO_REF:0000004
GO_REF:0000004
GO_REF:0000023

IEA: Inferred from Electronic Annotation

SP_KW:KW-0997
SP_KW:KW-1003
SP_SL:SL-0037

C

Seeded from EcoCyc [5]

complete

GO:0005886

plasma membrane

GO_REF:0000004
GO_REF:0000004
GO_REF:0000023

IEA: Inferred from Electronic Annotation

SP_KW:KW-0997
SP_KW:KW-1003
SP_SL:SL-0037

C

Seeded from EcoCyc

complete

GO:0006754

ATP biosynthetic process

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0066

P

Seeded from EcoCyc

complete

GO:0006810

transport

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0813

P

Seeded from EcoCyc

complete

GO:0006811

ion transport

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0406

P

Seeded from EcoCyc

complete

GO:0015078

hydrogen ion transmembrane transporter activity

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0375

F

Seeded from EcoCyc

complete

GO:0015986

ATP synthesis coupled proton transport

GO_REF:0000002
PMID:6294057[7]

IMP: Inferred from Mutant Phenotype

InterPro:IPR000711

P

Seeded from EcoCyc

complete

GO:0015992

proton transport

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0375

P

Seeded from EcoCyc

complete

GO:0016020

membrane

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0472

C

Seeded from EcoCyc

complete

GO:0045261

proton-transporting ATP synthase complex, catalytic core F(1)

GO_REF:0000002
GO_REF:0000004
PMID:6294057[7]

IMP: Inferred from Mutant Phenotype

InterPro:IPR000711
SP_KW:KW-0139

C

Seeded from EcoCyc

complete

GO:0046872

metal ion binding

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0066

F

Seeded from EcoCyc

complete

GO:0046933

hydrogen ion transporting ATP synthase activity, rotational mechanism

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000711

F

Seeded from EcoCyc

complete

GO:0046961

proton-transporting ATPase activity, rotational mechanism

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000711

F

Seeded from EcoCyc

complete

GO:0015986

ATP synthesis coupled proton transport

PMID:6294057[7]

IMP: Inferred from Mutant Phenotype

P

Seeded from EcoCyc 11.1[3].

complete

Contributes to

GO:0046933

hydrogen ion transporting ATP synthase activity, rotational mechanism

PMID:2863270[8]

IDA: Inferred from Direct Assay

F

complete

GO:0045261

proton-transporting ATP synthase complex, catalytic core F(1)

PMID:6294057[7]

IMP: Inferred from Mutant Phenotype

C

Component of F1 complex, with gene products of uncA (alpha), uncD (beta), uncG (gamma) and uncC (epsilon) - for review see Chap 19 of Escherichia coli and Salmonella: Cellular and Molecular Biology, 2nd Edition.

complete

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Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type Partner Notes References Evidence

Protein

Subunits of ATP synthase, F1 complex

could be indirect

Protein

iscS

PMID:16606699[9]

Experiment(s):EBI-1146620

Protein

glpC

PMID:16606699[9]

Experiment(s):EBI-1146620

Protein

atpA

PMID:16606699[9]

Experiment(s):EBI-1146620

Protein

glpD

PMID:16606699[9]

Experiment(s):EBI-1146620

Protein

yjjK

PMID:16606699[9]

Experiment(s):EBI-1146620

Protein

dnaK

PMID:16606699[9]

Experiment(s):EBI-1146620

Protein

atpD

PMID:16606699[9]

Experiment(s):EBI-1146620

Protein

Subunits of ATP synthase

could be indirect


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Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

Compartment Description Evidence Notes

plasma membrane

From EcoCyc[3]

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Notes

Structure and Physical Properties

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Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Sequence

at EcoCyc 

MSEFITVARP YAKAAFDFAV EHQSVERWQD MLAFAAEVTK NEQMAELLSG ALAPETLAES
FIAVCGEQLD ENGQNLIRVM AENGRLNALP DVLEQFIHLR AVSEATAEVD VISAAALSEQ
QLAKISAAME KRLSRKVKLN CKIDKSVMAG VIIRAGDMVI DGSVRGRLER LADVLQS
Length

177

Mol. Wt

19.331 kDa

pI

5.0 (calculated)

Extinction coefficient

6,990 - 7,240 (calc based on 1 Y, 1 W, and 2 C residues)

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Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Type Residues Description Notes
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<motif_map/>

Structure
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

<beststructure>atpH 562</beststructure>

Models

View models at:

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Structure figures

Notes

Gene Product Resources

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See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type Source Notes/Reference
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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

EcoCyc (EcoliWiki Page)

EcoCyc:ATPH-MONOMER

UniProt (EcoliWiki Page)

UniProt:P0ABA4

PFAM (EcoliWiki Page)

PFAM:PF00213

RefSeq (EcoliWiki Page)

RefSeq:NP_418191

ModBase (EcoliWiki Page)

ModBase:P0ABA4

PDB (EcoliWiki Page)

PDB:1ABV


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Notes

Links

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Name URL Comments
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References

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See Help:References for how to manage references in EcoliWiki.

  1. ↑ 1.0 1.1 1.2 1.3 1.4 1.5 1.6 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 2.4 2.5 2.6 2.7 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ 3.0 3.1 3.2 3.3 3.4 3.5 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  5. ↑ 5.00 5.01 5.02 5.03 5.04 5.05 5.06 5.07 5.08 5.09 EcoCyc (release 13.0; 2009) Keseler, IM et al. (2009) Nucleic Acids Res. 37(Database issue):D464-70
  6. ↑ 6.0 6.1 6.2 6.3 EcoCyc (release 12.5; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  7. ↑ 7.0 7.1 7.2 7.3 Humbert, R et al. (1983) Escherichia coli mutants defective in the uncH gene. J. Bacteriol. 153 416-22 PubMed
  8. ↑ Klionsky, DJ & Simoni, RD (1985) Assembly of a functional F1 of the proton-translocating ATPase of Escherichia coli. J. Biol. Chem. 260 11200-6 PubMed
  9. ↑ 9.0 9.1 9.2 9.3 9.4 9.5 9.6 Arifuzzaman, M et al. (2006) Large-scale identification of protein-protein interaction of Escherichia coli K-12. Genome Res. 16 686-91 PubMed

Categories

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