rho:Quickview

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions
Gene Name

rho (synonyms: ECK3775, b3783, JW3756, nitA, nusD, psuA, rnsC, sun, tsu, psu, sbaA)[1]

Product(s)

Rho product[1]: transcription termination factor product, B3783 product, RnsC product, Tsu product, Sun product, NusD product, Psu product, SbaA product, PsuA product, NitA product

Description

transcription termination factor Rho monomer; polarity suppressor[2][3]

Component of transcription termination factor Rho[3]

Knock-Out Phenotype
Regulation/Expression

transcription unit(s): rhoL[2], rhoL-rho[2], rho

Regulation/Activity


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Notes

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The rho gene is often misannotated as a polarity suppressor. Mutations in rho suppress polarity.[4][5][6][7][8] Wild type rho is the source of polarity.

rho has been shown to be an essential gene (Das, 1976; Bubunenko, 2007).[9]



References

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  1. ↑ 1.0 1.1 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ Das, A et al. (1976) Isolation and characterization of conditional lethal mutants of Escherichia coli defective in transcription termination factor rho. Proc. Natl. Acad. Sci. U.S.A. 73 1959-63 PubMed
  5. ↑ Korn, LJ & Yanofsky, C (1976) Polarity suppressors defective in transcription termination at the attenuator of the tryptophan operon of Escherichia coli have altered rho factor. J. Mol. Biol. 106 231-41 PubMed
  6. ↑ Belfort, M & Oppenheim, AB (1976) Efficient suppression of the requirement for N function of bacteriophage lambda by a Rho-defective E.coli suA mutant. Mol. Gen. Genet. 148 171-3 PubMed
  7. ↑ Richardson, JP & Carey, JL 3rd (1982) rho Factors from polarity suppressor mutants with defects in their RNA interactions. J. Biol. Chem. 257 5767-71 PubMed
  8. ↑ Das, A et al. (1978) Interaction of RNA polymerase and rho in transcription termination: coupled ATPase. Proc. Natl. Acad. Sci. U.S.A. 75 4828-32 PubMed
  9. ↑ EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.