rho:Quickview
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| Quickview | Gene | Gene Product(s) | Expression | Evolution | On One Page |
| References | Suggestions |
<protect>
| Standard Name |
rho |
|---|---|
| Gene Synonym(s) |
ECK3775, b3783, JW3756, nitA, nusD, psuA, rnsC, sun, tsu, psu, sbaA, suA[1], hdf, tabC |
| Product Desc. |
transcription termination factor Rho; polarity suppressor[2][3]; Component of transcription termination factor Rho[3] Transcription termination factor Rho; bicyclomycin target[4] |
| Product Synonyms(s) |
transcription termination factor[1], B3783[2][1], RnsC[2][1], Tsu[2][1], Sun[2][1], NusD[2][1], Psu[2][1], SbaA[2][1], PsuA[2][1], NitA[2][1], Rho[2][1] , ECK3775, hdf, JW3756, nitA, nusD, psuA, rnsC, sbaA, sun, tabC, tsu, b3783 |
| Function from GO |
<GO_nr /> |
| Knock-Out Phenotype | |
| Regulation/Expression | |
| Regulation/Activity | |
| Quick Links |
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| edit table |
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Notes
- The rho gene is often misannotated as a polarity suppressor. Mutations in rho suppress polarity.[5][6][7][8][9] Wild type rho is the source of polarity.
- rho has been shown to be an essential gene (Das, 1976; Bubunenko, 2007).[4]
- rho is required to maintain genomic integrity by resolving transcription/replication conflicts [10]
References
- ↑ 1.00 1.01 1.02 1.03 1.04 1.05 1.06 1.07 1.08 1.09 1.10 1.11 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
- ↑ 2.00 2.01 2.02 2.03 2.04 2.05 2.06 2.07 2.08 2.09 2.10 2.11 2.12 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
- ↑ Das, A et al. (1976) Isolation and characterization of conditional lethal mutants of Escherichia coli defective in transcription termination factor rho. Proc. Natl. Acad. Sci. U.S.A. 73 1959-63 PubMed
- ↑ Korn, LJ & Yanofsky, C (1976) Polarity suppressors defective in transcription termination at the attenuator of the tryptophan operon of Escherichia coli have altered rho factor. J. Mol. Biol. 106 231-41 PubMed
- ↑ Belfort, M & Oppenheim, AB (1976) Efficient suppression of the requirement for N function of bacteriophage lambda by a Rho-defective E.coli suA mutant. Mol. Gen. Genet. 148 171-3 PubMed
- ↑ Richardson, JP & Carey, JL 3rd (1982) rho Factors from polarity suppressor mutants with defects in their RNA interactions. J. Biol. Chem. 257 5767-71 PubMed
- ↑ Das, A et al. (1978) Interaction of RNA polymerase and rho in transcription termination: coupled ATPase. Proc. Natl. Acad. Sci. U.S.A. 75 4828-32 PubMed
- ↑ Washburn, RS & Gottesman, ME (2011) Transcription termination maintains chromosome integrity. Proc. Natl. Acad. Sci. U.S.A. 108 792-7 PubMed
