putA:Quickview
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| Quickview | Gene | Gene Product(s) | Expression | Evolution | On One Page |
| References | Suggestions |
| Gene Name |
putA (synonyms: ECK1005, b1014, JW0999, poaA, putC, proline utilization A)[1][2] |
|---|---|
| Product(s) |
PutA product[1]: fused DNA-binding transcriptional regulator product, proline dehydrogenase product, pyrroline-5-carboxylate dehydrogenase product, B1014 product, PutC product, PoaA product |
| Description |
PutA bifunctional enzyme and transcriptional regulator[2] PutA transcriptional repressor, Proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase[3] |
| Knock-Out Phenotype | |
| Regulation/Expression | |
| Regulation/Activity |
|
| edit table |
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Notes
PutA is a multifunctional membrane-associated flavoprotein involved in proline catabolism: the central proline dehydrogenese domain feeds its product to the C-terminal Delta(1)-pyrroline-5-carboxylate dehydrogenese domain, to produce glutamate. The N-terminal 90 residue domain is the DNA-binding repressor domain. A divergon is a regulon comprised of two adjacent divergent operons or genes. Binds TrxA (Kumar, 2004).[4]
References
- ↑ 1.0 1.1 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
- ↑ 2.0 2.1 2.2 2.3 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.