emrE:Quickview

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions
Gene Name

emrE (synonyms: ECK0534, b0543, JW0531, mvrC, eb, mvrB, G6299)[1][2]

Product(s)

EmrE product[1]: DLP12 prophage; multidrug resistance protein product, B0543 product, MvrC product

Description

EmrE SMR transporter[2][3]

Knock-Out Phenotype
Regulation/Expression

transcription unit(s): renD[2]

Regulation/Activity


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Notes

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EmrE defunct PDB structures 1S7B and 2F2M, and any conclusions derived from these structures, have been retracted due to a software data inversion error (Ma, 2007; Chang, 2007). Correct structures are now available. EmrE belongs to the SMR efflux pump family, DMT superfamily. EmrE accomplishes multidrug efflux by coupling conformational changes between two heterodimers with proton gradient. Dual-topology membrane protein.[4]



References

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  1. ↑ 1.0 1.1 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.