ada:Gene Product(s)

Standard name	Ada product
Synonyms	fused DNA-binding transcriptional dual regulator product^[1], O6-methylguanine-DNA methyltransferase product^[1], B2213 product^[2]^[1], Ada product^[2]^[1]
Product description	Ada transcriptional dual regulator^[2]^[3]
EC number (for enzymes)	2.1.1.63^[1]
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Notes

Function

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Gene Ontology

Qualifier	GO ID	GO term name	Reference(s)	Evidence Code	with/from	Aspect	Notes	Status
	GO:0006281	DNA_repair	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR014048	P	Seeded from EcoCyc 12.5 ^[4]
	GO:0043565	sequence-specific_DNA_binding	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR000005	F	Seeded from EcoCyc 12.5 ^[4]
	GO:0016740	transferase_activity	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0808	F	Seeded from EcoCyc 12.5 ^[4]
	GO:0008270	zinc_ion_binding	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0862	F	Seeded from EcoCyc 12.5 ^[4]
	GO:0008270	zinc_ion_binding	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR004026	F	Seeded from EcoCyc 12.5 ^[4]
	GO:0008168	methyltransferase_activity	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0489	F	Seeded from EcoCyc 12.5 ^[4]
	GO:0008168	methyltransferase_activity	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR004026	F	Seeded from EcoCyc 12.5 ^[4]
	GO:0006974	response_to_DNA_damage_stimulus	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0227	P	Seeded from EcoCyc 12.5 ^[4]
	GO:0006355	regulation_of_transcription,_DNA-dependent	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0805	P	Seeded from EcoCyc 12.5 ^[4]
	GO:0006355	regulation_of_transcription,_DNA-dependent	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR004026	P	Seeded from EcoCyc 12.5 ^[4]
	GO:0006355	regulation_of_transcription,_DNA-dependent	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR000005	P	Seeded from EcoCyc 12.5 ^[4]
	GO:0006281	DNA_repair	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0234	P	Seeded from EcoCyc 12.5 ^[4]
	GO:0006281	DNA_repair	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR008332	P	Seeded from EcoCyc 12.5 ^[4]
	GO:0006281	DNA_repair	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR004026	P	Seeded from EcoCyc 12.5 ^[4]
	GO:0003908	methylated-DNA-[protein]-cysteine_S-methyltransferase_activity	GO_REF:0000003	IEA: Inferred from Electronic Annotation	EC:2.1.1.63	F	Seeded from EcoCyc 12.5 ^[4]
	GO:0005622	intracellular	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR000005	C	Seeded from EcoCyc 12.5 ^[4]
	GO:0003908	methylated-DNA-[protein]-cysteine_S-methyltransferase_activity	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR008332	F	Seeded from EcoCyc 12.5 ^[4]
	GO:0003908	methylated-DNA-[protein]-cysteine_S-methyltransferase_activity	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR001497	F	Seeded from EcoCyc 12.5 ^[4]
	GO:0003824	catalytic_activity	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR014048	F	Seeded from EcoCyc 12.5 ^[4]
	GO:0003700	transcription_factor_activity	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR000005	F	Seeded from EcoCyc 12.5 ^[4]
	GO:0003677	DNA_binding	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0238	F	Seeded from EcoCyc 12.5 ^[4]
	GO:0003677	DNA_binding	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR004026	F	Seeded from EcoCyc 12.5 ^[4]
	GO:0005737	cytoplasm				C	Seeded from EcoCyc 11.1^[3].	required fields missing
	GO:0006281	DNA_repair	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR001497	P	Seeded from EcoCyc 12.5 ^[4]
	GO:0006350	transcription	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0804	P	Seeded from EcoCyc 12.5 ^[4]
	GO:0016563	transcription activator activity				F	Seeded from EcoCyc 11.1^[3].	required fields missing
	GO:0016564	transcription repressor activity				F	Seeded from EcoCyc 11.1^[3].	required fields missing
	GO:0046872	metal_ion_binding	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0479	F	Seeded from EcoCyc 12.5 ^[4]
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Interactions

Partner Type	Partner	Notes
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Notes

Localization

Compartment	Description	Evidence	Notes
membrane			From EcoCyc^[3]
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Notes

Structure and Physical Properties

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Physical Properties

Sequence	at EcoCyc MKKATCLTDD QRWQSVLARD PNADGEFVFA VRTTGIFCRP SCRARHALRE NVSFYANASE ALAAGFRPCK RCQPEKANAQ QHRLDKITHA CRLLEQETPV TLEALADQVA MSPFHLHRLF KATTGMTPKA WQQAWRARRL RESLAKGESV TTSILNAGFP DSSSYYRKAD ETLGMTAKQF RHGGENLAVR YALADCELGR CLVAESERGI CAILLGDDDA TLISELQQMF PAADNAPADL MFQQHVREVI ASLNQRDTPL TLPLDIRGTA FQQQVWQALR TIPCGETVSY QQLANAIGKP KAVRAVASAC AANKLAIIIP CHRVVRGDGT LSGYRWGVSR KAQLLRREAE NEER
Mol. Wt	39.32 kDa (calc) ^[2]
pI	8.69^[2]
Extinction coefficient	36440 - 37940 (calc based on 6 Y, 5 W, and 12 C residues)
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Domains/Motifs/Modification Sites

Type	Residues	Description	Notes
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Structure

Structure Type	Organism	Accession	Residues covered	Notes
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Notes

Gene Product Resources

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Resource type	Source	Notes/Reference
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Notes

Accessions in Other Databases

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Database	Accession	Notes
EcoCyc (EcoliWiki Page)	EcoCyc:PD00230
UniProt (EcoliWiki Page)	UniProt:P06134
PFAM (EcoliWiki Page)	PFAM:PF02805
RefSeq (EcoliWiki Page)	RefSeq:NP_416717
ModBase (EcoliWiki Page)	ModBase:P06134
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Notes

Links

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Name	URL	Comments
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References

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↑ ^1.0 ^1.1 ^1.2 ^1.3 ^1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
↑ ^2.0 ^2.1 ^2.2 ^2.3 ^2.4 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
↑ ^3.0 ^3.1 ^3.2 ^3.3 ^3.4 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
↑ ^4.00 ^4.01 ^4.02 ^4.03 ^4.04 ^4.05 ^4.06 ^4.07 ^4.08 ^4.09 ^4.10 ^4.11 ^4.12 ^4.13 ^4.14 ^4.15 ^4.16 ^4.17 ^4.18 ^4.19 ^4.20 ^4.21 ^4.22 ^4.23 ^4.24 EcoCyc (release 12.5; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7

ada:Gene Product(s)

Nomenclature

Notes

Function

Notes

Localization

Notes

Structure and Physical Properties

Notes

Gene Product Resources

Notes

Accessions in Other Databases

Notes

Links

References

Categories

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ada:Gene Product(s)

Nomenclature

Notes

Function

Notes

Localization

Notes

Structure and Physical Properties

Notes

Gene Product Resources

Notes

Accessions in Other Databases

Notes

Links

References

Categories

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