cysB:Gene Product(s)
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| Quickview | Gene | Gene Product(s) | Expression | Evolution | On One Page |
| Nomenclature | Function | Interactions | Localization | Sequence | Structure | Resources | Accessions | Links | References | Suggestions |
Nomenclature
| Standard name |
CysB product |
|---|---|
| Synonyms |
DNA-binding transcriptional dual regulator, O-acetyl-L-serine-binding product[1], B1275 product[2][1], CysB product[2][1], positive transcriptional regulator for cysteine regulon product[2][1] |
| Product description |
Component of ; CysB transcriptional dual regulator[2][3] |
| EC number (for enzymes) |
|
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Notes
Function
Gene Ontology
| Qualifier | GO ID | GO term name | Reference(s) | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0006350 |
transcription |
P |
Seeded from EcoCyc 11.1[3]. |
required fields missing | ||||
|
NOT |
GO:0019344 |
cysteine biosynthetic process |
P |
Seeded from EcoCyc 11.1[3]. CysB is a regulator of genes involved in the cystein biosynthetic process |
required field missing | |||
| GO:0016564 |
transcription repressor activity |
IDA: Inferred from Direct Assay |
F |
Seeded from EcoCyc 11.1[3]. |
complete | |||
| GO:0005737 |
cytoplasm |
C |
Seeded from EcoCyc 11.1[3]. |
required fields missing | ||||
| GO:0016563 |
transcription activator activity |
F |
Seeded from EcoCyc 11.1[3]. |
required fields missing | ||||
| GO:0016564 |
transcription repressor activity |
IDA: Inferred from Direct Assay |
F |
Seeded from EcoCyc 11.1[3]. |
complete | |||
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Interactions
| Partner Type | Partner | Notes |
|---|---|---|
|
Protein |
Subunits of CysB transcriptional dual regulator |
could be indirect |
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Notes
Localization
| Compartment | Description | Evidence | Notes |
|---|---|---|---|
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Notes
Structure and Physical Properties
Physical Properties
| Sequence |
MKLQQLRYIV EVVNHNLNVS STAEGLYTSQ PGISKQVRML EDELGIQIFS RSGKHLTQVT PAGQEIIRIA REVLSKVDAI KSVAGEHTWP DKGSLYIATT HTQARYALPN VIKGFIERYP RVSLHMHQGS PTQIADAVSK GNADFAIATE ALHLYEDLVM LPCYHWNRAI VVTPDHPLAG KKAITIEELA QYPLVTYTFG FTGRSELDTA FNRAGLTPRI VFTATDADVI KTYVRLGLGV GVIASMAVDP VADPDLVRVD AHDIFSHSTT KIGFRRSTFL RSYMYDFIQR FAPHLTRDVV DAAVALRSNE EIEVMFKDIK LPEK |
|---|---|
| Mol. Wt |
36.15 kDa (calc) [2] |
| pI |
7.25[2] |
| Extinction coefficient |
28880 - 29005 (calc based on 12 Y, 2 W, and 1 C residues) |
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Domains/Motifs/Modification Sites
| Type | Residues | Description | Notes |
|---|---|---|---|
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Structure
| Structure Type | Organism | Accession | Residues covered | Notes |
|---|---|---|---|---|
|
X-RAY DIFFRACTION |
Klebsiella aerogenes |
1AL3 COFACTOR BINDING FRAGMENT OF CYSB FROM KLEBSIELLA AEROGENES |
||
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Notes
Gene Product Resources
| Resource type | Source | Notes/Reference |
|---|---|---|
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Notes
Accessions in Other Databases
| Database | Accession | Notes |
|---|---|---|
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Notes
Links
| Name | URL | Comments |
|---|---|---|
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References
See Help:References for how to manage references in EcoliWiki.
- ↑ 1.0 1.1 1.2 1.3 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
- ↑ 2.0 2.1 2.2 2.3 2.4 2.5 2.6 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ 3.0 3.1 3.2 3.3 3.4 3.5 3.6 3.7 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ van Der Ploeg, JR et al. (1999) The Escherichia coli ssuEADCB gene cluster is required for the utilization of sulfur from aliphatic sulfonates and is regulated by the transcriptional activator Cbl. J. Biol. Chem. 274 29358-65 PubMed
- ↑ Jagura-Burdzy, G & Hulanicka, D (1981) Use of gene fusions to study expression of cysB, the regulatory gene of the cysteine regulon. J. Bacteriol. 147 744-51 PubMed
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