putA:Quickview
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| Quickview | Gene | Gene Product(s) | Expression | Evolution | On One Page |
| References | Suggestions |
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| Standard Name |
putA |
|---|---|
| Gene Synonym(s) |
ECK1005, b1014, JW0999, poaA, putC, proline utilization A[1][2] |
| Product Desc. |
PutA bifunctional enzyme and transcriptional regulator[2]; PutA transcriptional repressor, Proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase[3]; Component of PUTA-CPLX[2]; PutA transcriptional repressor, Proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase[3] Proline dehydrogenase and repressor for the putAP divergon[4] |
| Product Synonyms(s) |
fused DNA-binding transcriptional regulator[1], proline dehydrogenase[1], pyrroline-5-carboxylate dehydrogenase[1], B1014[2][1], PutC[2][1], PoaA[2][1], PutA[2][1] |
| Function from GO |
<GO_nr /> |
| Knock-Out Phenotype | |
| Regulation/Expression | |
| Regulation/Activity | |
| Quick Links |
PortEco search(putA) DNA display Protein display Pubmed(putA) Textpresso(putA) |
| edit table |
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Notes
PutA is a multifunctional membrane-associated flavoprotein involved in proline catabolism: the central proline dehydrogenese domain feeds its product to the C-terminal Delta(1)-pyrroline-5-carboxylate dehydrogenese domain, to produce glutamate. The N-terminal 90 residue domain is the DNA-binding repressor domain. A divergon is a regulon comprised of two adjacent divergent operons or genes. Binds TrxA (Kumar, 2004).[4]
References
- ↑ 1.0 1.1 1.2 1.3 1.4 1.5 1.6 1.7 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
- ↑ 2.0 2.1 2.2 2.3 2.4 2.5 2.6 2.7 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.