sad:Gene Product(s): Difference between revisions

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Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
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complete
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GO:0004777
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succinate-semialdehyde dehydrogenase activity
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PMID:17873044<br />PMID:17873044
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IDA: Inferred from Direct Assay
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<br />
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F
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Seeded from EcoCyc
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complete
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GO:0005737
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cytoplasm
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PMID:7011797
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IDA: Inferred from Direct Assay
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C
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Seeded from EcoCyc
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complete
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GO:0006527
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arginine catabolic process
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PMID:17873044
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IMP: Inferred from Mutant Phenotype
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P
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Seeded from EcoCyc
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complete
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GO:0006807
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nitrogen compound metabolic process
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PMID:17873044
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IDA: Inferred from Direct Assay
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P
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Seeded from EcoCyc
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complete
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GO:0008152
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metabolic process
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GO_REF:0000002<br />GO_REF:0000002<br />GO_REF:0000002<br />GO_REF:0000002
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IEA: Inferred from Electronic Annotation
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InterPro:IPR015590<br />InterPro:IPR016160<br />InterPro:IPR016161<br />InterPro:IPR016162
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P
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Seeded from EcoCyc
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complete
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GO:0009013
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succinate-semialdehyde dehydrogenase (NAD(P)+) activity
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PMID:17873044<br />PMID:7011797
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IDA: Inferred from Direct Assay
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<br />
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F
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Seeded from EcoCyc
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complete
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GO:0009447
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putrescine catabolic process
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PMID:17873044
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IMP: Inferred from Mutant Phenotype
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P
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Seeded from EcoCyc
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complete
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GO:0009450
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gamma-aminobutyric acid catabolic process
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PMID:17873044<br />PMID:7009588<br />PMID:7011797
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IMP: Inferred from Mutant Phenotype
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<br /><br />
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P
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Seeded from EcoCyc
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complete
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GO:0016491
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oxidoreductase activity
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GO_REF:0000002<br />GO_REF:0000002<br />GO_REF:0000002<br />GO_REF:0000002<br />GO_REF:0000004
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IEA: Inferred from Electronic Annotation
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InterPro:IPR015590<br />InterPro:IPR016160<br />InterPro:IPR016161<br />InterPro:IPR016162<br />SP_KW:KW-0560
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F
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Seeded from EcoCyc
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complete
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GO:0055114
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oxidation reduction
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GO_REF:0000004
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IEA: Inferred from Electronic Annotation
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SP_KW:KW-0560
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P
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Seeded from EcoCyc
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complete  
complete  

Revision as of 17:25, 5 October 2009

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.

Standard name

Sad

Synonyms

predicted aldehyde dehydrogenase[1], B1525[2][1], YneI[2][1]

Product description

G6811[2][3]

EC number (for enzymes)


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Notes

Function

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Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference(s) Evidence Code with/from Aspect Notes Status
GO:0005737

cytoplasm

PMID:7011797[4]

IDA: Inferred from Direct Assay

C

Seeded from EcoCyc [5]

complete

GO:0006527

arginine catabolic process

PMID:17873044[6]

IMP: Inferred from Mutant Phenotype

P

Seeded from EcoCyc [5]

complete

GO:0006807

nitrogen compound metabolic process

PMID:17873044[6]

IDA: Inferred from Direct Assay

P

Seeded from EcoCyc [5]

complete

GO:0008152

metabolic process

GO_REF:0000002
GO_REF:0000002
GO_REF:0000002
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR015590
InterPro:IPR016160
InterPro:IPR016161
InterPro:IPR016162

P

Seeded from EcoCyc [5]

complete

GO:0009447

putrescine catabolic process

PMID:17873044[6]

IMP: Inferred from Mutant Phenotype

P

Seeded from EcoCyc [5]

complete

GO:0016491

oxidoreductase activity

GO_REF:0000002
GO_REF:0000002
GO_REF:0000002
GO_REF:0000002
GO_REF:0000004

IEA: Inferred from Electronic Annotation

InterPro:IPR015590
InterPro:IPR016160
InterPro:IPR016161
InterPro:IPR016162
SP_KW:KW-0560

F

Seeded from EcoCyc [5]

complete

GO:0055114

oxidation reduction

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0560

P

Seeded from EcoCyc [5]

complete

GO:0009013

succinate-semialdehyde dehydrogenase (NAD(P)+) activity

PMID:17873044[6]

IDA: Inferred from Direct Assay

F

complete

GO:0004777

succinate-semialdehyde dehydrogenase activity

PMID:17873044[6]

IDA: Inferred from Direct Assay

F

complete

GO:0009013

succinate-semialdehyde dehydrogenase (NAD(P)+) activity

PMID:7011797[4]

IDA: Inferred from Direct Assay

F

complete

GO:0009450

gamma-aminobutyric acid catabolic process

PMID:17873044[6]

IMP: Inferred from Mutant Phenotype

P

complete

GO:0009450

gamma-aminobutyric acid catabolic process

PMID:7011797[4]

IMP: Inferred from Mutant Phenotype

P

complete

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Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type Partner Notes References Evidence
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Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

Compartment Description Evidence Notes
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Notes

Structure and Physical Properties

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Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Sequence

at EcoCyc 

MTHKGDTPMT ITPATHAISI NPATGEQLSV LPWAGADDIE NALQLAAAGF RDWRETNIDY
RAEKLRDIGK ALRARSEEMA QMITREMGKP INQARAEVAK SANLCDWYAE HGPAMLKAEP
TLVENQQAVI EYRPLGTILA IMPWNFPLWQ VMRGAVPIIL AGNGYLLKHA PNVMGCAQLI
AQVFKDAGIP QGVYGWLNAD NDGVSQMIKD SRIAAVTVTG SVRAGAAIGA QAGAALKKCV
LELGGSDPFI VLNDADLELA VKAAVAGRYQ NTGQVCAAAK RFIIEEGIAS AFTERFVAAA
AALKMGDPRD EENALGPMAR FDLRDELHHQ VEKTLAQGAR LLLGGEKMAG AGNYYPPTVL
ANVTPEMTAF REEMFGPVAA ITIAKDAEHA LELANDSEFG LSATIFTTDE TQARQMAARL
ECGGVFINGY CASDARVAFG GVKKSGFGRE LSHFGLHEFC NIQTVWKDRI
Length

470

Mol. Wt

50.586 kDa

pI

5.6 (calculated)

Extinction coefficient

51,910 - 52,785 (calc based on 9 Y, 7 W, and 7 C residues)

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Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Type Residues Description Notes
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<motif_map/>

Structure
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

<beststructure> gene=sad taxon=562,83333 </beststructure>

Models

View models at:

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Structure figures

Notes

Gene Product Resources

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See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type Source Notes/Reference
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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

EcoCyc (EcoliWiki Page)

EcoCyc:G6811-MONOMER

UniProt (EcoliWiki Page)

UniProt:P76149

PFAM (EcoliWiki Page)

PFAM:PF00171

RefSeq (EcoliWiki Page)

RefSeq:NP_416042

ModBase (EcoliWiki Page)

ModBase:P76149


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Notes

Links

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Name URL Comments
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References

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See Help:References for how to manage references in EcoliWiki.

  1. ↑ 1.0 1.1 1.2 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ 4.0 4.1 4.2 Donnelly, MI & Cooper, RA (1981) Succinic semialdehyde dehydrogenases of Escherichia coli: their role in the degradation of p-hydroxyphenylacetate and gamma-aminobutyrate. Eur. J. Biochem. 113 555-61 PubMed
  5. ↑ 5.0 5.1 5.2 5.3 5.4 5.5 5.6 EcoCyc (release 13.0; 2009) Keseler, IM et al. (2009) Nucleic Acids Res. 37(Database issue):D464-70
  6. ↑ 6.0 6.1 6.2 6.3 6.4 6.5 Fuhrer, T et al. (2007) Computational prediction and experimental verification of the gene encoding the NAD+/NADP+-dependent succinate semialdehyde dehydrogenase in Escherichia coli. J. Bacteriol. 189 8073-8 PubMed

Categories

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