endA:Gene Product(s): Difference between revisions

Standard name	EndA
Synonyms	DNA-specific endonuclease I^[1], B2945^[2]^[1], EndA^[2]^[1]
Product description	DNA-specific endonuclease I^[2]^[3] DNA-specific endonuclease I, periplasmic; inhibited by RNA; extensive DNA breakdown^[4]
EC number (for enzymes)	3.1.21.1^[1]
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Notes

Function

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Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier	GO ID	GO term name	Reference(s)	Evidence Code	with/from	Aspect	Notes	Status
	GO:0042597	periplasmic space	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0574	C	Seeded from EcoCyc 12.5 ^[5]	complete
	GO:0016787	hydrolase activity	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0378	F	Seeded from EcoCyc ^[6]	complete
	GO:0004530	deoxyribonuclease I activity	GO_REF:0000003	IEA: Inferred from Electronic Annotation	EC:3.1.21.1	F	Seeded from EcoCyc ^[6]	complete
	GO:0004519	endonuclease activity	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0255	F	Seeded from EcoCyc ^[6]	complete
	GO:0004518	nuclease activity	GO_REF:0000002 GO_REF:0000004	IEA: Inferred from Electronic Annotation	InterPro:IPR007346 SP_KW:KW-0540	F	Seeded from EcoCyc ^[6]	complete
	GO:0030288	outer membrane-bounded periplasmic space				C	Seeded from Riley et al 2006 ^[1].	required fields missing
	GO:0004518	nuclease activity	GO_REF:0000002 GO_REF:0000004	IEA: Inferred from Electronic Annotation	InterPro:IPR007346 SP_KW:KW-0540	F	Seeded from EcoCyc	complete
	GO:0004519	endonuclease activity	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0255	F	Seeded from EcoCyc	complete
	GO:0004530	deoxyribonuclease I activity	GO_REF:0000003	IEA: Inferred from Electronic Annotation	EC:3.1.21.1	F	Seeded from EcoCyc	complete
	GO:0016787	hydrolase activity	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0378	F	Seeded from EcoCyc	complete
	GO:0042597	periplasmic space	GO_REF:0000004 GO_REF:0000023	IEA: Inferred from Electronic Annotation	SP_KW:KW-0574 SP_SL:SL-0200	C	Seeded from EcoCyc	complete
	GO:0006308	DNA catabolic process				P	Seeded from Riley et al 2006 ^[1].	required fields missing
	GO:0000737	DNA catabolic process, endonucleolytic				P	Seeded from EcoCyc 11.1^[3].	required fields missing
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Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type	Partner	Notes	References	Evidence
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Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

Compartment	Description	Evidence	Notes
periplasm
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Notes

Structure and Physical Properties

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Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Sequence	at EcoCyc MYRYLSIAAV VLSAAFSGPA LAEGINSFSQ AKAAAVKVHA DAPGTFYCGC KINWQGKKGV VDLQSCGYQV RKNENRASRV EWEHVVPAWQ FGHQRQCWQD GGRKNCAKDP VYRKMESDMH NLQPSVGEVN GDRGNFMYSQ WNGGEGQYGQ CAMKVDFKEK AAEPPARARG AIARTYFYMR DQYNLTLSRQ QTQLFNAWNK MYPVTDWECE RDERIAKVQG NHNPYVQRAC QARKS
Length	235
Mol. Wt	26.707 kDa
pI	9.4 (calculated)
Extinction coefficient	56,380 - 57,380 (calc based on 12 Y, 7 W, and 8 C residues)
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Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Type	Residues	Description	Notes
motif	1-22	UniProt Manual:Signal Peptides	UniProt:P25736
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<motif_map/>

Structure See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

Models

View models at:

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Notes

Gene Product Resources

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See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type	Source	Notes/Reference
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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database	Accession	Notes
EcoCyc (EcoliWiki Page)	EcoCyc:EG11336-MONOMER
SwissModel (EcoliWiki Page)	SwissModel:P25736
UniProt (EcoliWiki Page)	UniProt:P25736
PFAM (EcoliWiki Page)	PFAM:PF04231
RefSeq (EcoliWiki Page)	RefSeq:NP_417420
ModBase (EcoliWiki Page)	ModBase:P25736
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Notes

Links

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Name	URL	Comments
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References

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See Help:References for how to manage references in EcoliWiki.

↑ ^1.0 ^1.1 ^1.2 ^1.3 ^1.4 ^1.5 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
↑ ^2.0 ^2.1 ^2.2 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
↑ ^3.0 ^3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
↑ EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
↑ EcoCyc (release 12.5; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
↑ ^6.0 ^6.1 ^6.2 ^6.3 EcoCyc (release 13.0; 2009) Keseler, IM et al. (2009) Nucleic Acids Res. 37(Database issue):D464-70

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 ==References==
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 __NOTOC__
-</noinclude>
 ===Categories===
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 [[Category:Proteins]]
 [[Category:GO:0030288_!_outer membrane-bounded periplasmic space]][[Category:GO:0006308_!_DNA catabolic process]][[Category:GO:0000737_!_DNA catabolic process, endonucleolytic]][[Category:Location:periplasm]]

endA:Gene Product(s): Difference between revisions

Revision as of 18:41, 26 June 2009

Nomenclature

Notes

Function

Notes

Localization

Notes

Structure and Physical Properties

Notes

Gene Product Resources

Notes

Accessions in Other Databases

Notes

Links

References

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