lysP:Gene Product(s): Difference between revisions

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[http://www.ebi.ac.uk/interpro/DisplayIproEntry?ac=IPR002293 InterPro:IPR002293]<br />[http://www.ebi.ac.uk/interpro/DisplayIproEntry?ac=IPR004841 InterPro:IPR004841]<br />[http://www.uniprot.org/keywords/KW-0397 SP_KW:KW-0397]<br />[http://www.uniprot.org/keywords/KW-0472 SP_KW:KW-0472]
[http://www.ebi.ac.uk/interpro/DisplayIproEntry?ac=IPR002293 InterPro:IPR002293]<br />[http://www.ebi.ac.uk/interpro/DisplayIproEntry?ac=IPR004841 InterPro:IPR004841]<br />[http://www.uniprot.org/keywords/KW-0397 SP_KW:KW-0397]<br />[http://www.uniprot.org/keywords/KW-0472 SP_KW:KW-0472]
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C
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Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
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complete
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[[Category:GO:0016021_!_integral_to_membrane]][http://gowiki.tamu.edu/wiki/index.php/Category:GO:0016021_!_integral_to_membrane GO:0016021]
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integral to membrane
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[http://www.geneontology.org/cgi-bin/references.cgi#GO_REF:0000002 GO_REF:0000002]<br />[http://www.geneontology.org/cgi-bin/references.cgi#GO_REF:0000004 GO_REF:0000004]
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IEA: Inferred from Electronic Annotation
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[http://www.ebi.ac.uk/interpro/DisplayIproEntry?ac=IPR004840 InterPro:IPR004840]<br />[http://www.uniprot.org/keywords/KW-0812 SP_KW:KW-0812]
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C
C
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required fields missing   
required fields missing   
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[[Category:GO:0016021_!_integral_to_membrane]][http://gowiki.tamu.edu/wiki/index.php/Category:GO:0016021_!_integral_to_membrane GO:0016021]
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integral to membrane
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[http://www.geneontology.org/cgi-bin/references.cgi#GO_REF:0000002 GO_REF:0000002]<br />[http://www.geneontology.org/cgi-bin/references.cgi#GO_REF:0000004 GO_REF:0000004]
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IEA: Inferred from Electronic Annotation
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[http://www.ebi.ac.uk/interpro/DisplayIproEntry?ac=IPR004840 InterPro:IPR004840]<br />[http://www.uniprot.org/keywords/KW-0812 SP_KW:KW-0812]
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C
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Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
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complete


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!|Partner Type!!Partner!!Notes!!References


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Revision as of 00:12, 20 November 2008

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

Standard name

LysP product

Synonyms

lysine transporter product[1], B2156 product[2][1], CadR product[2][1], LysP product[2][1]

Product description

LysP lysine APC transporter[2][3]

EC number (for enzymes)
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See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.

Notes

Function

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Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference(s) Evidence Code with/from Aspect Notes Status
GO:0006810

transport

GO_REF:0000002
GO_REF:0000004

IEA: Inferred from Electronic Annotation

InterPro:IPR004841
SP_KW:KW-0813

P

Seeded from EcoCyc 12.5 [4]

complete

GO:0006865

amino acid transport

GO_REF:0000002
GO_REF:0000002
GO_REF:0000004

IEA: Inferred from Electronic Annotation

InterPro:IPR002293
InterPro:IPR004840
SP_KW:KW-0029

P

Seeded from EcoCyc 12.5 [4]

complete

GO:0015171

amino acid transmembrane transporter activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR002293

F

Seeded from EcoCyc 12.5 [4]

complete

GO:0016020

membrane

GO_REF:0000002
GO_REF:0000002
GO_REF:0000004
GO_REF:0000004

IEA: Inferred from Electronic Annotation

InterPro:IPR002293
InterPro:IPR004841
SP_KW:KW-0397
SP_KW:KW-0472

C

Seeded from EcoCyc 12.5 [4]

complete

GO:0016021

integral to membrane

GO_REF:0000002
GO_REF:0000004

IEA: Inferred from Electronic Annotation

InterPro:IPR004840
SP_KW:KW-0812

C

Seeded from EcoCyc 12.5 [4]

complete

GO:0009089

lysine biosynthetic process via diaminopimelate

P

Seeded from EcoCyc 11.1[3].

required fields missing

GO:0015292

uniporter activity

F

Seeded from EcoCyc 11.1[3].

required fields missing

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Interactions

Partner Type Partner Notes References
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See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Notes

Localization

Compartment Description Evidence Notes

plasma membrane

C-terminus localized in the cytoplasm with 12 predicted transmembrane domains

Daley et al. (2005) [5]

plasma membrane

From EcoCyc[3]

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See Help:Product_localization for how to add or edit information in this section of EcoliWiki.


Notes

Structure and Physical Properties

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Physical Properties

Sequence

at EcoCyc 

MVSETKTTEA PGLRRELKAR HLTMIAIGGS IGTGLFVASG ATISQAGPGG ALLSYMLIGL
MVYFLMTSLG ELAAYMPVSG SFATYGQNYV EEGFGFALGW NYWYNWAVTI AVDLVAAQLV
MSWWFPDTPG WIWSALFLGV IFLLNYISVR GFGEAEYWFS LIKVTTVIVF IIVGVLMIIG
IFKGAQPAGW SNWTIGEAPF AGGFAAMIGV AMIVGFSFQG TELIGIAAGE SEDPAKNIPR
AVRQVFWRIL LFYVFAILII SLIIPYTDPS LLRNDVKDIS VSPFTLVFQH AGLLSAAAVM
NAVILTAVLS AGNSGMYAST RMLYTLACDG KAPRIFAKLS RGGVPRNALY ATTVIAGLCF
LTSMFGNQTV YLWLLNTSGM TGFIAWLGIA ISHYRFRRGY VLQGHDINDL PYRSGFFPLG
PIFAFILCLI ITLGQNYEAF LKDTIDWGGV AATYIGIPLF LIIWFGYKLI KGTHFVRYSE
MKFPQNDKK
Mol. Wt

53.58 kDa (calc) [2]

pI
Extinction coefficient

115280 - 115655 (calc based on 22 Y, 15 W, and 3 C residues)

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See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Domains/Motifs/Modification Sites

Type Residues Description Notes

Domain

370 - 392

Predicted membrane-spanning helix.

TMD predicted by TMHMM[6]

Domain

413 - 435

Predicted membrane-spanning helix.

TMD predicted by TMHMM[6]

Domain

445 - 467

Predicted membrane-spanning helix.

TMD predicted by TMHMM[6]

Domain

343 - 365

Predicted membrane-spanning helix.

TMD predicted by TMHMM[6]

Domain

21 - 43

Predicted membrane-spanning helix.

TMD predicted by TMHMM[6]

Domain

53 - 75

Predicted membrane-spanning helix.

TMD predicted by TMHMM[6]

Domain

103 - 125

Predicted membrane-spanning helix.

TMD predicted by TMHMM[6]

Domain

130 - 152

Predicted membrane-spanning helix.

TMD predicted by TMHMM[6]

Domain

159 - 181

Predicted membrane-spanning helix.

TMD predicted by TMHMM[6]

Domain

196 - 218

Predicted membrane-spanning helix.

TMD predicted by TMHMM[6]

Domain

245 - 267

Predicted membrane-spanning helix.

TMD predicted by TMHMM[6]

Domain

287 - 309

Predicted membrane-spanning helix.

TMD predicted by TMHMM[6]

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See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

tmhmm.php?gene=lysP&show=pic&.jpg
Click the image to view raw output from TMHMM.

Structure

Structures

<beststructure>lysP 562</beststructure>

Models

View models at:

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See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Notes

Gene Product Resources

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Resource type Source Notes/Reference
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Notes

Accessions in Other Databases

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Database Accession Notes

EcoCyc (EcoliWiki Page)

EcoCyc:LYSP-MONOMER

UniProt (EcoliWiki Page)

UniProt:P25737

PFAM (EcoliWiki Page)

PFAM:PF00324

RefSeq (EcoliWiki Page)

RefSeq:NP_416661


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Notes

Links

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Name URL Comments
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See Help:Links_table for how to enter or edit information in this section of EcoliWiki.



References

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See Help:References for how to manage references in EcoliWiki.

  1. ↑ 1.0 1.1 1.2 1.3 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 2.4 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ 3.0 3.1 3.2 3.3 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ 4.0 4.1 4.2 4.3 4.4 EcoCyc (release 12.5; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  5. ↑ Daley, DO et al. (2005) Global topology analysis of the Escherichia coli inner membrane proteome. Science 308 1321-3 PubMed
  6. ↑ 6.00 6.01 6.02 6.03 6.04 6.05 6.06 6.07 6.08 6.09 6.10 6.11 Krogh, A et al. (2001) Predicting transmembrane protein topology with a hidden Markov model: application to complete genomes. J. Mol. Biol. 305 567-80 PubMed


Categories

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