nei:Gene Product(s): Difference between revisions
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InterPro:IPR015886 | InterPro:IPR015886 | ||
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P | |||
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Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/> | |||
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complete | |||
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[[Category:GO:0006974_!_response_to_DNA_damage_stimulus]][http://gowiki.tamu.edu/wiki/index.php/Category:GO:0006974_!_response_to_DNA_damage_stimulus GO:0006974] | |||
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response to DNA damage stimulus | |||
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GO_REF:0000004 | |||
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IEA: Inferred from Electronic Annotation | |||
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SP_KW:KW-0227 | |||
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P | P | ||
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[[Category:GO: | [[Category:GO:0008152_!_metabolic_process]][http://gowiki.tamu.edu/wiki/index.php/Category:GO:0008152_!_metabolic_process GO:0008152] | ||
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metabolic process | |||
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GO_REF:0000004 | GO_REF:0000004 | ||
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IEA: Inferred from Electronic Annotation | IEA: Inferred from Electronic Annotation | ||
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SP_KW:KW- | SP_KW:KW-0326 | ||
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P | P | ||
Revision as of 23:17, 2 October 2008
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| Quickview | Gene | Gene Product(s) | Expression | Evolution | On One Page |
| Nomenclature | Function | Interactions | Localization | Sequence | Structure | Resources | Accessions | Links | References | Suggestions |
Nomenclature
| Standard name |
Nei product |
|---|---|
| Synonyms |
endonuclease VIII product[1], 5-formyluracil/5-hydroxymethyluracil DNA glycosylase product[1], B0714 product[2][1], Nei product[2][1] |
| Product description | |
| EC number (for enzymes) | |
| edit table | |
See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.
Notes
Function
Gene Ontology
| Qualifier | GO ID | GO term name | Reference(s) | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000703 |
oxidized pyrimidine base lesion DNA N-glycosylase activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc 12.5 [4] |
complete | |||
| GO:0003676 |
nucleic acid binding |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc 12.5 [4] |
complete | |||
| GO:0003677 |
DNA binding |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc 12.5 [4] |
complete | |||
| GO:0003677 |
DNA binding |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc 12.5 [4] |
complete | |||
| GO:0003684 |
damaged DNA binding |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc 12.5 [4] |
complete | |||
| GO:0003824 |
catalytic activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc 12.5 [4] |
complete | |||
| GO:0003824 |
catalytic activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc 12.5 [4] |
complete | |||
| GO:0003906 |
DNA-(apurinic or apyrimidinic site) lyase activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc 12.5 [4] |
complete | |||
| GO:0003906 |
DNA-(apurinic or apyrimidinic site) lyase activity |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc 12.5 [4] |
complete | |||
| GO:0006281 |
DNA repair |
IEA: Inferred from Electronic Annotation |
P |
Seeded from EcoCyc 12.5 [4] |
complete | |||
| GO:0006281 |
DNA repair |
IEA: Inferred from Electronic Annotation |
P |
Seeded from EcoCyc 12.5 [4] |
complete | |||
| GO:0006281 |
DNA repair |
IEA: Inferred from Electronic Annotation |
P |
Seeded from EcoCyc 12.5 [4] |
complete | |||
| GO:0006284 |
base-excision repair |
IEA: Inferred from Electronic Annotation |
P |
Seeded from EcoCyc 12.5 [4] |
complete | |||
| GO:0006289 |
nucleotide-excision repair |
IEA: Inferred from Electronic Annotation |
P |
Seeded from EcoCyc 12.5 [4] |
complete | |||
| GO:0006974 |
response to DNA damage stimulus |
IEA: Inferred from Electronic Annotation |
P |
Seeded from EcoCyc 12.5 [4] |
complete | |||
| GO:0005737 |
cytoplasm |
C |
Seeded from EcoCyc 11.1[3]. |
required fields missing | ||||
| GO:0008152 |
metabolic process |
IEA: Inferred from Electronic Annotation |
P |
Seeded from EcoCyc 12.5 [4] |
complete | |||
| edit table |
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.
Interactions
| Partner Type | Partner | Notes |
|---|---|---|
| edit table |
See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.
Notes
Localization
| Compartment | Description | Evidence | Notes |
|---|---|---|---|
| edit table |
See Help:Product_localization for how to add or edit information in this section of EcoliWiki.
Notes
Structure and Physical Properties
Physical Properties
| Sequence |
MPEGPEIRRA ADNLEAAIKG KPLTDVWFAF PQLKPYQSQL IGQHVTHVET RGKALLTHFS NDLTLYSHNQ LYGVWRVVDT GEEPQTTRVL RVKLQTADKT ILLYSASDIE MLTPEQLTTH PFLQRVGPDV LDPNLTPEVV KERLLSPRFR NRQFAGLLLD QAFLAGLGNY LRVEILWQVG LTGNHKAKDL NAAQLDALAH ALLEIPRFSY ATRGQVDENK HHGALFRFKV FHRDGEPCER CGSIIEKTTL SSRPFYWCPG CQH |
|---|---|
| Mol. Wt |
29.85 kDa (calc) [2] |
| pI | |
| Extinction coefficient |
32430 - 32930 (calc based on 7 Y, 4 W, and 4 C residues) |
| edit table | |
See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.
Domains/Motifs/Modification Sites
| Type | Residues | Description | Notes |
|---|---|---|---|
| edit table |
See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.
Structure
| Structure Type | Organism | Accession | Residues covered | Notes |
|---|---|---|---|---|
|
X-RAY DIFFRACTION |
synthetic construct |
1K3X Crystal structure of a trapped reaction intermediate of the DNA repair enzyme Endonuclease VIII with Brominated-DNA |
||
|
X-RAY DIFFRACTION |
synthetic construct |
1K3W Crystal structure of a trapped reaction intermediate of the DNA Repair Enzyme Endonuclease VIII with DNA |
||
| edit table |
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.
Notes
Gene Product Resources
| Resource type | Source | Notes/Reference |
|---|---|---|
| edit table |
See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.
Notes
Accessions in Other Databases
| Database | Accession | Notes |
|---|---|---|
| edit table |
See Help:Product_accessions for help entering or editing information in this section of EcoliWiki.
Notes
Links
| Name | URL | Comments |
|---|---|---|
| edit table |
See Help:Links_table for how to enter or edit information in this section of EcoliWiki.
References
See Help:References for how to manage references in EcoliWiki.
- ↑ 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
- ↑ 2.0 2.1 2.2 2.3 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ 4.00 4.01 4.02 4.03 4.04 4.05 4.06 4.07 4.08 4.09 4.10 4.11 4.12 4.13 4.14 4.15 EcoCyc (release 12.5; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
Categories
- GO:0000703 ! oxidized pyrimidine base lesion DNA N-glycosylase activity
- GO:0003676 ! nucleic acid binding
- GO:0003677 ! DNA binding
- GO:0003684 ! damaged DNA binding
- GO:0003824 ! catalytic activity
- GO:0003906 ! DNA-(apurinic or apyrimidinic site) lyase activity
- GO:0006281 ! DNA repair
- GO:0006284 ! base-excision repair
- GO:0006289 ! nucleotide-excision repair
- GO:0006974 ! response to DNA damage stimulus
- GO:0005737 ! cytoplasm
- GO:0008152 ! metabolic process
- Proteins
- Products with structures in PDB