nei:Gene Product(s): Difference between revisions

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!|Qualifier!!GO ID!!GO term name!!Reference(s)!!Evidence Code!!with/from!!Aspect!!Notes!!Status
!|Qualifier!!GO ID!!GO term name!!Reference(s)!!Evidence Code!!with/from!!Aspect!!Notes!!Status
|-
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[[Category:GO:0016798_!_hydrolase_activity,_acting_on_glycosyl_bonds]][http://gowiki.tamu.edu/wiki/index.php/Category:GO:0016798_!_hydrolase_activity,_acting_on_glycosyl_bonds GO:0016798]
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hydrolase_activity,_acting_on_glycosyl_bonds
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[http://www.geneontology.org/cgi-bin/references.cgi/#GO_REF:0000004 GO_REF:0000004]<br />
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IEA: Inferred from Electronic Annotation
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SP_KW:KW-0326
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F
|
Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
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|-
|
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[[Category:GO:0016829_!_lyase_activity]][http://gowiki.tamu.edu/wiki/index.php/Category:GO:0016829_!_lyase_activity GO:0016829]
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lyase_activity
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[http://www.geneontology.org/cgi-bin/references.cgi/#GO_REF:0000004 GO_REF:0000004]<br />
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IEA: Inferred from Electronic Annotation
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SP_KW:KW-0456
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F
|
Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
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|-
|
|
[[Category:GO:0008270_!_zinc_ion_binding]][http://gowiki.tamu.edu/wiki/index.php/Category:GO:0008270_!_zinc_ion_binding GO:0008270]
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zinc_ion_binding
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[http://www.geneontology.org/cgi-bin/references.cgi/#GO_REF:0000002 GO_REF:0000002]<br />
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IEA: Inferred from Electronic Annotation
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InterPro:IPR012319
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F
|
Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
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|-
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|
[[Category:GO:0008270_!_zinc_ion_binding]][http://gowiki.tamu.edu/wiki/index.php/Category:GO:0008270_!_zinc_ion_binding GO:0008270]
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zinc_ion_binding
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[http://www.geneontology.org/cgi-bin/references.cgi/#GO_REF:0000002 GO_REF:0000002]<br />
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IEA: Inferred from Electronic Annotation
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InterPro:IPR015886
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F
|
Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
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|-
|
|
[[Category:GO:0008270_!_zinc_ion_binding]][http://gowiki.tamu.edu/wiki/index.php/Category:GO:0008270_!_zinc_ion_binding GO:0008270]
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zinc_ion_binding
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[http://www.geneontology.org/cgi-bin/references.cgi/#GO_REF:0000004 GO_REF:0000004]<br />
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IEA: Inferred from Electronic Annotation
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SP_KW:KW-0862
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F
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Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
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|-
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[[Category:GO:0008534_!_oxidized_purine_base_lesion_DNA_N-glycosylase_activity]][http://gowiki.tamu.edu/wiki/index.php/Category:GO:0008534_!_oxidized_purine_base_lesion_DNA_N-glycosylase_activity GO:0008534]
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purine-specific_oxidized_base_lesion_DNA_N-glycosylase_activity
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[http://www.geneontology.org/cgi-bin/references.cgi/#GO_REF:0000002 GO_REF:0000002]<br />
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IEA: Inferred from Electronic Annotation
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InterPro:IPR012319
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F
|
Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
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|-
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[[Category:GO:0016787_!_hydrolase_activity]][http://gowiki.tamu.edu/wiki/index.php/Category:GO:0016787_!_hydrolase_activity GO:0016787]
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hydrolase_activity
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[http://www.geneontology.org/cgi-bin/references.cgi/#GO_REF:0000004 GO_REF:0000004]<br />
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IEA: Inferred from Electronic Annotation
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SP_KW:KW-0378
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F
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Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
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|-
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[[Category:GO:0006281_!_DNA_repair]][http://gowiki.tamu.edu/wiki/index.php/Category:GO:0006281_!_DNA_repair GO:0006281]
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DNA_repair
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[http://www.geneontology.org/cgi-bin/references.cgi/#GO_REF:0000002 GO_REF:0000002]<br />
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IEA: Inferred from Electronic Annotation
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InterPro:IPR000214
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P
|
Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
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|-
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[[Category:GO:0006281_!_DNA_repair]][http://gowiki.tamu.edu/wiki/index.php/Category:GO:0006281_!_DNA_repair GO:0006281]
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DNA_repair
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[http://www.geneontology.org/cgi-bin/references.cgi/#GO_REF:0000004 GO_REF:0000004]<br />
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IEA: Inferred from Electronic Annotation
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SP_KW:KW-0234
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P
|
Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
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|-
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[[Category:GO:0006284_!_base-excision_repair]][http://gowiki.tamu.edu/wiki/index.php/Category:GO:0006284_!_base-excision_repair GO:0006284]
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base-excision_repair
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[http://www.geneontology.org/cgi-bin/references.cgi/#GO_REF:0000002 GO_REF:0000002]<br />
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IEA: Inferred from Electronic Annotation
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InterPro:IPR012319
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P
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Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
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|-
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[[Category:GO:0006289_!_nucleotide-excision_repair]][http://gowiki.tamu.edu/wiki/index.php/Category:GO:0006289_!_nucleotide-excision_repair GO:0006289]
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nucleotide-excision_repair
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[http://www.geneontology.org/cgi-bin/references.cgi/#GO_REF:0000002 GO_REF:0000002]<br />
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IEA: Inferred from Electronic Annotation
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InterPro:IPR015886
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P
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Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
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|-
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[[Category:GO:0006974_!_response_to_DNA_damage_stimulus]][http://gowiki.tamu.edu/wiki/index.php/Category:GO:0006974_!_response_to_DNA_damage_stimulus GO:0006974]
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response_to_DNA_damage_stimulus
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[http://www.geneontology.org/cgi-bin/references.cgi/#GO_REF:0000004 GO_REF:0000004]<br />
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IEA: Inferred from Electronic Annotation
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SP_KW:KW-0227
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P
|
Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
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|-
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[[Category:GO:0008152_!_metabolic_process]][http://gowiki.tamu.edu/wiki/index.php/Category:GO:0008152_!_metabolic_process GO:0008152]
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metabolism
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[http://www.geneontology.org/cgi-bin/references.cgi/#GO_REF:0000004 GO_REF:0000004]<br />
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IEA: Inferred from Electronic Annotation
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SP_KW:KW-0326
|
P
|
Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
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|-
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[[Category:GO:0008270_!_zinc_ion_binding]][http://gowiki.tamu.edu/wiki/index.php/Category:GO:0008270_!_zinc_ion_binding GO:0008270]
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zinc_ion_binding
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[http://www.geneontology.org/cgi-bin/references.cgi/#GO_REF:0000002 GO_REF:0000002]<br />
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IEA: Inferred from Electronic Annotation
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InterPro:IPR000214
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F
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Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
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|-
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[[Category:GO:0000703_!_oxidized_pyrimidine_base_lesion_DNA_N-glycosylase_activity]][http://gowiki.tamu.edu/wiki/index.php/Category:GO:0000703_!_oxidized_pyrimidine_base_lesion_DNA_N-glycosylase_activity GO:0000703]
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pyrimidine-specific_oxidized_base_lesion_DNA_N-glycosylase_activity
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[http://www.geneontology.org/cgi-bin/references.cgi/#GO_REF:0000020 GO_REF:0000020]<br />
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IEA: Inferred from Electronic Annotation
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HAMAP:MF_01253
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F
|
Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
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|-
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[[Category:GO:0003676_!_nucleic_acid_binding]][http://gowiki.tamu.edu/wiki/index.php/Category:GO:0003676_!_nucleic_acid_binding GO:0003676]
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nucleic_acid_binding
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[http://www.geneontology.org/cgi-bin/references.cgi/#GO_REF:0000002 GO_REF:0000002]<br />
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IEA: Inferred from Electronic Annotation
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InterPro:IPR010979
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F
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Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
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|-
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[[Category:GO:0003677_!_DNA_binding]][http://gowiki.tamu.edu/wiki/index.php/Category:GO:0003677_!_DNA_binding GO:0003677]
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DNA_binding
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[http://www.geneontology.org/cgi-bin/references.cgi/#GO_REF:0000002 GO_REF:0000002]<br />
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IEA: Inferred from Electronic Annotation
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InterPro:IPR015886
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F
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Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
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|-
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[[Category:GO:0003677_!_DNA_binding]][http://gowiki.tamu.edu/wiki/index.php/Category:GO:0003677_!_DNA_binding GO:0003677]
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DNA_binding
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[http://www.geneontology.org/cgi-bin/references.cgi/#GO_REF:0000004 GO_REF:0000004]<br />
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IEA: Inferred from Electronic Annotation
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SP_KW:KW-0238
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F
|
Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
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|-
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|
[[Category:GO:0003684_!_damaged_DNA_binding]][http://gowiki.tamu.edu/wiki/index.php/Category:GO:0003684_!_damaged_DNA_binding GO:0003684]
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damaged_DNA_binding
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[http://www.geneontology.org/cgi-bin/references.cgi/#GO_REF:0000002 GO_REF:0000002]<br />
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IEA: Inferred from Electronic Annotation
|
InterPro:IPR012319
|
F
|
Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
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|-
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[[Category:GO:0003824_!_catalytic_activity]][http://gowiki.tamu.edu/wiki/index.php/Category:GO:0003824_!_catalytic_activity GO:0003824]
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catalytic_activity
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[http://www.geneontology.org/cgi-bin/references.cgi/#GO_REF:0000002 GO_REF:0000002]<br />
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IEA: Inferred from Electronic Annotation
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InterPro:IPR015886
|
F
|
Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
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|-
|
|
[[Category:GO:0003824_!_catalytic_activity]][http://gowiki.tamu.edu/wiki/index.php/Category:GO:0003824_!_catalytic_activity GO:0003824]
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catalytic_activity
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[http://www.geneontology.org/cgi-bin/references.cgi/#GO_REF:0000004 GO_REF:0000004]<br />
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0511
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F
|
Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
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|-
|
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[[Category:GO:0003906_!_DNA-(apurinic_or_apyrimidinic_site)_lyase_activity]][http://gowiki.tamu.edu/wiki/index.php/Category:GO:0003906_!_DNA-(apurinic_or_apyrimidinic_site)_lyase_activity GO:0003906]
|
DNA-(apurinic_or_apyrimidinic_site)_lyase_activity
|
[http://www.geneontology.org/cgi-bin/references.cgi/#GO_REF:0000020 GO_REF:0000020]<br />
|
IEA: Inferred from Electronic Annotation
|
HAMAP:MF_01253
|
F
|
Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
|
|-
|
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[[Category:GO:0003906_!_DNA-(apurinic_or_apyrimidinic_site)_lyase_activity]][http://gowiki.tamu.edu/wiki/index.php/Category:GO:0003906_!_DNA-(apurinic_or_apyrimidinic_site)_lyase_activity GO:0003906]
|
DNA-(apurinic_or_apyrimidinic_site)_lyase_activity
|
[http://www.geneontology.org/cgi-bin/references.cgi/#GO_REF:0000003 GO_REF:0000003]<br />
|
IEA: Inferred from Electronic Annotation
|
EC:4.2.99.18
|
F
|
Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
|
|-  
|-  
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Line 535: Line 98:


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[[Category:GO:0006281_!_DNA_repair]][http://gowiki.tamu.edu/wiki/index.php/Category:GO:0006281_!_DNA_repair GO:0006281]
[[Category:GO:0000703_!_oxidized_pyrimidine_base_lesion_DNA_N-glycosylase_activity]][http://gowiki.tamu.edu/wiki/index.php/Category:GO:0000703_!_oxidized_pyrimidine_base_lesion_DNA_N-glycosylase_activity GO:0000703]
|
|
DNA_repair
oxidized pyrimidine base lesion DNA N-glycosylase activity
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|
[http://www.geneontology.org/cgi-bin/references.cgi/#GO_REF:0000020 GO_REF:0000020]<br />
GO_REF:0000020
|
|
IEA: Inferred from Electronic Annotation
IEA: Inferred from Electronic Annotation
|
|
HAMAP:MF_01253
HAMAP:MF_01253
|
P
|
Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
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|-
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[[Category:GO:0046872_!_metal_ion_binding]][http://gowiki.tamu.edu/wiki/index.php/Category:GO:0046872_!_metal_ion_binding GO:0046872]
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metal_ion_binding
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[http://www.geneontology.org/cgi-bin/references.cgi/#GO_REF:0000004 GO_REF:0000004]<br />
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0479
|
|
F
F
Line 568: Line 112:
Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
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complete


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Revision as of 23:17, 2 October 2008

{{#css:Suppresslinks.css}}<css>h1 .editsection { display:none;} h2 .editsection { display:none;}</css>

Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
Nomenclature Function Interactions Localization Sequence Structure Resources Accessions Links References Suggestions

Nomenclature

Standard name

Nei product

Synonyms

endonuclease VIII product[1], 5-formyluracil/5-hydroxymethyluracil DNA glycosylase product[1], B0714 product[2][1], Nei product[2][1]

Product description

endonuclease VIII[2][3]

EC number (for enzymes)
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Notes

Function

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Gene Ontology

Qualifier GO ID GO term name Reference(s) Evidence Code with/from Aspect Notes Status
GO:0005737

cytoplasm

C

Seeded from EcoCyc 11.1[3].

required fields missing

GO:0000703

oxidized pyrimidine base lesion DNA N-glycosylase activity

GO_REF:0000020

IEA: Inferred from Electronic Annotation

HAMAP:MF_01253

F

Seeded from EcoCyc 12.5 [4]

complete

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See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Interactions

Partner Type Partner Notes
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See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Notes

Localization

Compartment Description Evidence Notes
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Notes

Structure and Physical Properties

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Physical Properties

Sequence

at EcoCyc 

MPEGPEIRRA ADNLEAAIKG KPLTDVWFAF PQLKPYQSQL IGQHVTHVET RGKALLTHFS
NDLTLYSHNQ LYGVWRVVDT GEEPQTTRVL RVKLQTADKT ILLYSASDIE MLTPEQLTTH
PFLQRVGPDV LDPNLTPEVV KERLLSPRFR NRQFAGLLLD QAFLAGLGNY LRVEILWQVG
LTGNHKAKDL NAAQLDALAH ALLEIPRFSY ATRGQVDENK HHGALFRFKV FHRDGEPCER
CGSIIEKTTL SSRPFYWCPG CQH
Mol. Wt

29.85 kDa (calc) [2]

pI
Extinction coefficient

32430 - 32930 (calc based on 7 Y, 4 W, and 4 C residues)

edit table

See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Domains/Motifs/Modification Sites

Type Residues Description Notes
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See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Structure

Structure Type Organism Accession Residues covered Notes

X-RAY DIFFRACTION

synthetic construct

1K3X Crystal structure of a trapped reaction intermediate of the DNA repair enzyme Endonuclease VIII with Brominated-DNA

X-RAY DIFFRACTION

synthetic construct

1K3W Crystal structure of a trapped reaction intermediate of the DNA Repair Enzyme Endonuclease VIII with DNA

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See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Notes

Gene Product Resources

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Resource type Source Notes/Reference
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Notes

Accessions in Other Databases

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Database Accession Notes

EcoCyc (EcoliWiki Page)

EcoCyc:G6383-MONOMER

UniProt (EcoliWiki Page)

UniProt:P50465

PFAM (EcoliWiki Page)

PFAM:PF01149

RefSeq (EcoliWiki Page)

RefSeq:NP_415242

ModBase (EcoliWiki Page)

ModBase:P50465

PDB (EcoliWiki Page)

PDB:1K3W

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See Help:Product_accessions for help entering or editing information in this section of EcoliWiki.

Notes

Links

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Name URL Comments
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See Help:Links_table for how to enter or edit information in this section of EcoliWiki.



References

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See Help:References for how to manage references in EcoliWiki.

  1. ↑ 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ EcoCyc (release 12.5; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7


Categories

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