nei:Gene Product(s): Difference between revisions

Standard name	Nei product
Synonyms	endonuclease VIII product^[1], 5-formyluracil/5-hydroxymethyluracil DNA glycosylase product^[1], B0714 product^[2]^[1], Nei product^[2]^[1]
Product description	endonuclease VIII^[2]^[3]
EC number (for enzymes)	3.2.-.-^[1]
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Notes

Function

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Gene Ontology

Qualifier	GO ID	GO term name	Reference(s)	Evidence Code	with/from	Aspect	Notes	Status
	GO:0000703	pyrimidine-specific_oxidized_base_lesion_DNA_N-glycosylase_activity	GO_REF:0000020	IEA: Inferred from Electronic Annotation	HAMAP:MF_01253	F	Seeded from EcoCyc 12.5 ^[4]
	GO:0003676	nucleic_acid_binding	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR010979	F	Seeded from EcoCyc 12.5 ^[4]
	GO:0003677	DNA_binding	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR015886	F	Seeded from EcoCyc 12.5 ^[4]
	GO:0003677	DNA_binding	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0238	F	Seeded from EcoCyc 12.5 ^[4]
	GO:0003684	damaged_DNA_binding	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR012319	F	Seeded from EcoCyc 12.5 ^[4]
	GO:0003824	catalytic_activity	GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR015886	F	Seeded from EcoCyc 12.5 ^[4]
	GO:0005737	cytoplasm				C	Seeded from EcoCyc 11.1^[3].	required fields missing
	GO:0006281	DNA repair				P	Seeded from EcoCyc 11.1^[3].	required fields missing
	GO:0003824	catalytic_activity	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0511	F	Seeded from EcoCyc 12.5 ^[4]
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Interactions

Partner Type	Partner	Notes
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Notes

Localization

Compartment	Description	Evidence	Notes
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Notes

Structure and Physical Properties

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Physical Properties

Sequence	at EcoCyc MPEGPEIRRA ADNLEAAIKG KPLTDVWFAF PQLKPYQSQL IGQHVTHVET RGKALLTHFS NDLTLYSHNQ LYGVWRVVDT GEEPQTTRVL RVKLQTADKT ILLYSASDIE MLTPEQLTTH PFLQRVGPDV LDPNLTPEVV KERLLSPRFR NRQFAGLLLD QAFLAGLGNY LRVEILWQVG LTGNHKAKDL NAAQLDALAH ALLEIPRFSY ATRGQVDENK HHGALFRFKV FHRDGEPCER CGSIIEKTTL SSRPFYWCPG CQH
Mol. Wt	29.85 kDa (calc) ^[2]
pI
Extinction coefficient	32430 - 32930 (calc based on 7 Y, 4 W, and 4 C residues)
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Domains/Motifs/Modification Sites

Type	Residues	Description	Notes
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Structure

Structure Type	Organism	Accession
X-RAY DIFFRACTION	synthetic construct	1K3X Crystal structure of a trapped reaction intermediate of the DNA repair enzyme Endonuclease VIII with Brominated-DNA
X-RAY DIFFRACTION	synthetic construct	1K3W Crystal structure of a trapped reaction intermediate of the DNA Repair Enzyme Endonuclease VIII with DNA
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Notes

Gene Product Resources

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Resource type	Source	Notes/Reference
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Notes

Accessions in Other Databases

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Database	Accession	Notes
EcoCyc (EcoliWiki Page)	EcoCyc:G6383-MONOMER
UniProt (EcoliWiki Page)	UniProt:P50465
PFAM (EcoliWiki Page)	PFAM:PF01149
RefSeq (EcoliWiki Page)	RefSeq:NP_415242
ModBase (EcoliWiki Page)	ModBase:P50465
PDB (EcoliWiki Page)	PDB:1K3W
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Notes

Links

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Name	URL	Comments
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References

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↑ ^1.0 ^1.1 ^1.2 ^1.3 ^1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
↑ ^2.0 ^2.1 ^2.2 ^2.3 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
↑ ^3.0 ^3.1 ^3.2 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
↑ ^4.0 ^4.1 ^4.2 ^4.3 ^4.4 ^4.5 ^4.6 EcoCyc (release 12.5; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7

nei:Gene Product(s): Difference between revisions

Revision as of 03:32, 30 September 2008

Nomenclature

Notes

Function

Notes

Localization

Notes

Structure and Physical Properties

Notes

Gene Product Resources

Notes

Accessions in Other Databases

Notes

Links

References

Categories

Navigation menu

@@ Line 164: / Line 164: @@
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 InterPro:IPR012319
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+F
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+Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
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+|-
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+[[Category:GO:0003824_!_catalytic_activity]][http://gowiki.tamu.edu/wiki/index.php/Category:GO:0003824_!_catalytic_activity GO:0003824]
+|
+catalytic_activity
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+[http://www.geneontology.org/cgi-bin/references.cgi/#GO_REF:0000002 GO_REF:0000002]<br />
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+IEA: Inferred from Electronic Annotation
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+InterPro:IPR015886
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 F
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 catalytic_activity
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-[http://www.geneontology.org/cgi-bin/references.cgi/#GO_REF:0000002 GO_REF:0000002]<br />
+[http://www.geneontology.org/cgi-bin/references.cgi/#GO_REF:0000004 GO_REF:0000004]<br />
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 IEA: Inferred from Electronic Annotation
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-InterPro:IPR015886
+SP_KW:KW-0511
 |
 F

nei:Gene Product(s): Difference between revisions

Revision as of 03:32, 30 September 2008

Nomenclature

Notes

Function

Notes

Localization

Notes

Structure and Physical Properties

Notes

Gene Product Resources

Notes

Accessions in Other Databases

Notes

Links

References

Categories

Navigation menu

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