Essential genes: Difference between revisions
Table edited by JimHu via TableEdit |
Table edited by JimHu via TableEdit |
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[[PMID:15466019]]<ref name=PMID:15466019/> | [[PMID:15466019]]<ref name=PMID:15466019/> | ||
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rpsF, rpsI, rpsM, rpsO, rpsQ, and rpsT | |||
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[[PMID:7751274]]<ref name=PMID:7751274/> | |||
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Revision as of 05:03, 22 August 2008
Introduction and caveats
This page displays a list of E. coli genes that may be essential. The list is generated by removing all genes where Keio deletions have been isolated, and all ins genes that are from insertion elements. The list was then manually curated to remove obvious pseudogenes. Community curation is needed to improve the quality of this list. Genes can be removed from the list by editing the list of gene pages in the wikitext of this page
<essentialGenes> nonessential gene 1:Gene nonessential gene 2:Gene etc. </essentialGenes>
tRNA genes that can be mutated to nonsense suppressors are marked as nonessential. Note that in many cases these are redundant and not all copies of a tRNA isoacceptor can be simultaneously deleted. Similarly, although ribosomal RNA genes are not on this list, at least one of each rRNA is needed for viability.
The list (Edit this)
<essentialGenes> List nonessential gene pages here arpB_2:Gene efeU_2:Gene folA:Gene gatR_2:Gene glnU:Gene glnV:Gene glnX:Gene lacZ:Gene leuX:Gene lysT:Gene mazE:Gene mazF:Gene micF:Gene ilvG_2:Gene istR-1:Gene istR-2:Gene molR_3:Gene rrfA:Gene rrfB:Gene rrfC:Gene rrfD:Gene rrfE:Gene rrfF:Gene rrfG:Gene rrfH:Gene rrsA:Gene rrsB:Gene rrsC:Gene rrsD:Gene rrsE:Gene rrsF:Gene rrsG:Gene rrsH:Gene rrlA:Gene rrlB:Gene rrlC:Gene rrlD:Gene rrlE:Gene rrlF:Gene rrlG:Gene rrlH:Gene serU:Gene serV:Gene ssrA:Gene tusB:Gene tusC:Gene tusD:Gene tusE:Gene tyrT:Gene wbbL_1:Gene yedN_1:Gene yeeL_1:Gene yfaS_1:Gene yi82_1:Gene ylbE_2:Gene yjgX_1:Gene </essentialGenes>
Evidence
Add evidence for nonessentiality here:
| Gene | Reference(s) | Comments |
|---|---|---|
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micF |
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rpsF, rpsI, rpsM, rpsO, rpsQ, and rpsT |
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| edit table |
Add evidence for essentiality here:
| Gene | Reference(s) | Comments |
|---|---|---|
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nusA |
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nusE |
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nusG |
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| edit table |
References
See Help:References for how to manage references in EcoliWiki.
- ↑ Krishnan, BR & Berg, DE (1993) Viability of folA-null derivatives of wild-type (thyA+) Escherichia coli K-12. J. Bacteriol. 175 909-11 PubMed
- ↑ Chen, S et al. (2004) MicC, a second small-RNA regulator of Omp protein expression in Escherichia coli. J. Bacteriol. 186 6689-97 PubMed
- ↑ Liu, MY et al. (1995) The product of the pleiotropic Escherichia coli gene csrA modulates glycogen biosynthesis via effects on mRNA stability. J. Bacteriol. 177 2663-72 PubMed
- ↑ 4.0 4.1 4.2 Bubunenko, M et al. (2007) Essentiality of ribosomal and transcription antitermination proteins analyzed by systematic gene replacement in Escherichia coli. J. Bacteriol. 189 2844-53 PubMed