coaE:Gene Product(s)

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Gene

Gene Product(s)

Expression

Evolution

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Nomenclature

Function

Interactions

Localization

Sequence

Domains

Structure

Resources

Accessions

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References

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Nomenclature

See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.

Standard name	CoaE
Synonyms	dephospho-CoA kinase, B0103, YacE, CoaE
Product description	EG12312 Dephospho-CoA kinase; final step in CoA synthesis
EC number (for enzymes)	2.7.1.24
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Notes

yacE is reported to encode dephospho-CoA kinase, which catalyzes the final step of Coenzyme A anabolism.

Function

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Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier	GO ID	GO term name	Reference(s)	Evidence Code	with/from	Aspect	Notes	Status
	GO:0030288	outer membrane-bounded periplasmic space				C	Seeded from Riley et al 2006 .	required fields missing
	GO:0000166	nucleotide binding	GOA:spkw SP_KW:GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0547	F	Seeded from EcoCyc (v14.0)
	GO:0004140	dephospho-CoA kinase activity	GOA:hamap GO_REF:0000020	IEA: Inferred from Electronic Annotation	HAMAP:MF_00376	F	Seeded from EcoCyc (v14.0)
	GO:0004140	dephospho-CoA kinase activity	GOA:interpro GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR001977	F	Seeded from EcoCyc (v14.0)
	GO:0004140	dephospho-CoA kinase activity	GOA:spec GO_REF:0000003	IEA: Inferred from Electronic Annotation	EC:2.7.1.24	F	Seeded from EcoCyc (v14.0)
	GO:0005524	ATP binding	GOA:hamap GO_REF:0000020	IEA: Inferred from Electronic Annotation	HAMAP:MF_00376	F	Seeded from EcoCyc (v14.0)
	GO:0005524	ATP binding	GOA:interpro GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR001977	F	Seeded from EcoCyc (v14.0)
	GO:0005524	ATP binding	GOA:spkw SP_KW:GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0067	F	Seeded from EcoCyc (v14.0)
	GO:0005737	cytoplasm	GOA:hamap GO_REF:0000020	IEA: Inferred from Electronic Annotation	HAMAP:MF_00376	C	Seeded from EcoCyc (v14.0)
	GO:0005737	cytoplasm	GOA:spkw SP_KW:GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0963	C	Seeded from EcoCyc (v14.0)
	GO:0005737	cytoplasm	GO_REF:0000023	IEA: Inferred from Electronic Annotation	SP_SL:SL-0086	C	Seeded from EcoCyc (v14.0)
	GO:0015937	coenzyme A biosynthetic process	GOA:hamap GO_REF:0000020	IEA: Inferred from Electronic Annotation	HAMAP:MF_00376	P	Seeded from EcoCyc (v14.0)
	GO:0015937	coenzyme A biosynthetic process	GOA:interpro GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR001977	P	Seeded from EcoCyc (v14.0)
	GO:0015937	coenzyme A biosynthetic process	GOA:spkw SP_KW:GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0173	P	Seeded from EcoCyc (v14.0)
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Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type	Partner	Notes	References	Evidence
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Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

Compartment	Description	Evidence	Source	Notes
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Structure and Physical Properties

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Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Sequence	at EcoCyc MRYIVALTGG IGSGKSTVAN AFADLGINVI DADIIARQVV EPGAPALHAI ADHFGANMIA ADGTLQRRAL RERIFANPEE KNWLNALLHP LIQQETQHQI QQATSPYVLW VVPLLVENSL YKKANRVLVV DVSPETQLKR TMQRDDVTRE HVEQILAAQA TREARLAVAD DVIDNNGAPD AIASDVARLH AHYLQLASQF VSQEKP
Length	206
Mol. Wt	22.621 kDa
pI	6.2 (calculated)
Extinction coefficient	16,960 (calc based on 4 Y, 2 W, and C residues)
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Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki. Type Residues Description Notes References edit table

<motif_map/>

Structure See Help:Product_structure for help entering or editing information in this section of EcoliWiki. Structures <beststructure> gene=coaE taxon=562,83333 </beststructure> Models View models at: EcoliPredict ModBase PSI-PRED Protein Quaternary Structure (PQS) Genomes TO Protein (GTOP) edit table

Gene Product Resources

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See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type	Source	Notes/Reference
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Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database	Accession	Notes
EcoCyc (EcoliWiki Page)	EcoCyc:EG12312-MONOMER
UniProt (EcoliWiki Page)	UniProt:P0A6I9
PFAM (EcoliWiki Page)	PFAM:PF01121
RefSeq (EcoliWiki Page)	RefSeq:NP_414645
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Links

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Name	URL	Comments
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References

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Categories

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