ada:Gene Product(s): Difference between revisions

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Fix GO terms with changed names.
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!|Qualifier!!GO ID!!GO term name!!Reference(s)!!Evidence Code!!with/from!!Aspect!!Notes!!Status
!|Qualifier!!GO ID!!GO term name!!Reference(s)!!Evidence Code!!with/from!!Aspect!!Notes!!Status
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GO:0005622
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intracellular
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GO_REF:0000002
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IEA: Inferred from Electronic Annotation
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InterPro:IPR000005
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C
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Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
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complete
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GO:0003908
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methylated-DNA-(protein)-cysteine S-methyltransferase activity
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GO_REF:0000002<br />GO_REF:0000002<br />GO_REF:0000003
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IEA: Inferred from Electronic Annotation
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InterPro:IPR001497<br />InterPro:IPR008332<br />EC:2.1.1.63
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F
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Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
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complete
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GO:0003677
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DNA binding
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GO_REF:0000002<br />GO_REF:0000004
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IEA: Inferred from Electronic Annotation
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InterPro:IPR004026<br />SP_KW:KW-0238
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F
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Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
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complete
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GO:0003700
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transcription factor activity
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GO_REF:0000002
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IEA: Inferred from Electronic Annotation
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InterPro:IPR000005
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F
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Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
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complete
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GO:0003824
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catalytic activity
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GO_REF:0000002
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IEA: Inferred from Electronic Annotation
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InterPro:IPR014048
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F
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Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
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complete
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GO:0046872
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metal ion binding
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GO_REF:0000004
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IEA: Inferred from Electronic Annotation
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SP_KW:KW-0479
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F
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Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
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complete
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GO:0016740
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transferase activity
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GO_REF:0000004
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IEA: Inferred from Electronic Annotation
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SP_KW:KW-0808
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F
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Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
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complete
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GO:0043565
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sequence-specific DNA binding
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GO_REF:0000002
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IEA: Inferred from Electronic Annotation
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InterPro:IPR000005
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F
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Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
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complete
|-
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GO:0006281
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DNA repair
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GO_REF:0000002<br />GO_REF:0000002<br />GO_REF:0000002<br />GO_REF:0000002<br />GO_REF:0000004
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IEA: Inferred from Electronic Annotation
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InterPro:IPR001497<br />InterPro:IPR004026<br />InterPro:IPR008332<br />InterPro:IPR014048<br />SP_KW:KW-0234
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P
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Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
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complete
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GO:0006350
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transcription<input name="field[2]" type="hidden" value="transcription" />
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GO_REF:0000004
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IEA: Inferred from Electronic Annotation
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SP_KW:KW-0804
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P
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Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
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complete
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GO:0006355
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regulation of transcription, DNA-dependent
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GO_REF:0000002<br />GO_REF:0000002<br />GO_REF:0000004
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IEA: Inferred from Electronic Annotation
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InterPro:IPR000005<br />InterPro:IPR004026<br />SP_KW:KW-0805
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P
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Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
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complete
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GO:0006974
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response to DNA damage stimulus
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GO_REF:0000004
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IEA: Inferred from Electronic Annotation
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SP_KW:KW-0227
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P
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Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
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complete
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GO:0008168
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methyltransferase activity
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GO_REF:0000002<br />GO_REF:0000004
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IEA: Inferred from Electronic Annotation
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InterPro:IPR004026<br />SP_KW:KW-0489
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F
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Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
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complete
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GO:0008270
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zinc ion binding
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GO_REF:0000002<br />GO_REF:0000004
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IEA: Inferred from Electronic Annotation
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InterPro:IPR004026<br />SP_KW:KW-0862
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F
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Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
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complete
|-
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GO:0005737
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cytoplasm
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C
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Seeded from EcoCyc 11.1<ref name='LIB:EcoCyc11.1'/>.
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required fields missing 
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GO:0016563
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transcription activator activity
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F
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Seeded from EcoCyc 11.1<ref name='LIB:EcoCyc11.1'/>.
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required fields missing 
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GO:0016564
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transcription repressor activity
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F
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Seeded from EcoCyc 11.1<ref name='LIB:EcoCyc11.1'/>.
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required fields missing 
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Revision as of 20:35, 10 June 2010

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.

Standard name

Ada

Synonyms

fused DNA-binding transcriptional dual regulator[1], O6-methylguanine-DNA methyltransferase[1], B2213[2][1], Ada[2][1]

Product description

Ada transcriptional dual regulator[2][3]

O6-methylguanine-DNA methyltransferase, transcription factor; inducible; DNA repair against methylating and alkylating agents; binds Zn(II)[4]

EC number (for enzymes)
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Notes

Function

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Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference(s) Evidence Code with/from Aspect Notes Status
GO:0008270

zinc ion binding

PMID:1581309[5]

IDA: Inferred from Direct Assay

F

N-terminal domain binds Zn

complete

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Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type Partner Notes References Evidence

Protein

rplB

PMID:16606699[6]

Experiment(s):EBI-1142195

Protein

rpsC

PMID:16606699[6]

Experiment(s):EBI-1142195

Protein

moeB

PMID:16606699[6]

Experiment(s):EBI-1142195

Protein

fur

PMID:16606699[6]

Experiment(s):EBI-1142195

Protein

rpsG

PMID:16606699[6]

Experiment(s):EBI-1142195

Protein

ybiA

PMID:16606699[6]

Experiment(s):EBI-1142195
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Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

Compartment Description Evidence Source Notes

membrane

From EcoCyc[3]


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Notes

Structure and Physical Properties

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Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Sequence

at EcoCyc 

MKKATCLTDD QRWQSVLARD PNADGEFVFA VRTTGIFCRP SCRARHALRE NVSFYANASE
ALAAGFRPCK RCQPEKANAQ QHRLDKITHA CRLLEQETPV TLEALADQVA MSPFHLHRLF
KATTGMTPKA WQQAWRARRL RESLAKGESV TTSILNAGFP DSSSYYRKAD ETLGMTAKQF
RHGGENLAVR YALADCELGR CLVAESERGI CAILLGDDDA TLISELQQMF PAADNAPADL
MFQQHVREVI ASLNQRDTPL TLPLDIRGTA FQQQVWQALR TIPCGETVSY QQLANAIGKP
KAVRAVASAC AANKLAIIIP CHRVVRGDGT LSGYRWGVSR KAQLLRREAE NEER
Length

354

Mol. Wt

39.323 kDa

pI

8.8 (calculated)

Extinction coefficient

36,440 - 37,940 (calc based on 6 Y, 5 W, and 12 C residues)

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Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Type Residues Description Notes References
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<motif_map/>

Structure
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

<beststructure> gene=ada taxon=562,83333 </beststructure>

Models

View models at:

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Structure figures

Notes

Gene Product Resources

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See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type Source Notes/Reference
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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

EcoCyc (EcoliWiki Page)

EcoCyc:PD00230

UniProt (EcoliWiki Page)

UniProt:P06134

PFAM (EcoliWiki Page)

PFAM:PF02805

RefSeq (EcoliWiki Page)

RefSeq:NP_416717


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Notes

Links

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References

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See Help:References for how to manage references in EcoliWiki.

  1. ↑ 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  5. ↑ Myers, LC et al. (1992) Zinc binding by the methylation signaling domain of the Escherichia coli Ada protein. Biochemistry 31 4541-7 PubMed
  6. ↑ 6.0 6.1 6.2 6.3 6.4 6.5 Arifuzzaman, M et al. (2006) Large-scale identification of protein-protein interaction of Escherichia coli K-12. Genome Res. 16 686-91 PubMed

Categories

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