mhpF:Gene Product(s): Difference between revisions

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touch the Product_motif_table table.
Table edited by Kbguillory via TableEdit
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required fields missing   
required fields missing   
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GO:0005515
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protein binding
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PMID:16782065
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IDA: Inferred from Direct Assay
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C
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complete
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GO:0008774
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acetaldehyde dehydrogenase (acetylating) activity
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PMID:9098055
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IDA: Inferred from Direct Assay
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F
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complete


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Revision as of 22:48, 3 May 2010

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.

Standard name

MhpF

Synonyms

acetaldehyde-CoA dehydrogenase II, NAD-binding[1], B0351[2][1], MhpF[2][1]

Product description

acetaldehyde dehydrogenase 2[2][3]

Acetaldehyde dehydrogenase, acylating; utilizes MHP[4]

EC number (for enzymes)


Notes

Function

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Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference(s) Evidence Code with/from Aspect Notes Status
GO:0005737

cytoplasm

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000534

C

Seeded from EcoCyc [5]

complete

GO:0006520

amino acid metabolic process

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000534

P

Seeded from EcoCyc [5]

complete

GO:0008774

acetaldehyde dehydrogenase (acetylating) activity

GO_REF:0000003

IEA: Inferred from Electronic Annotation

EC:1.2.1.10

F

Seeded from EcoCyc 12.5 [6]

complete

GO:0016491

oxidoreductase activity

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0560

F

Seeded from EcoCyc [5]

complete

GO:0016620

oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000534

F

Seeded from EcoCyc [5]

complete

GO:0019439

aromatic compound catabolic process

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0058

P

Seeded from EcoCyc 12.5 [6]

complete

GO:0051287

NAD or NADH binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000534

F

Seeded from EcoCyc [5]

complete

GO:0003824

catalytic activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR016040

F

Seeded from EcoCyc [5]

complete

GO:0005488

binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR016040

F

Seeded from EcoCyc [5]

complete

GO:0008152

metabolic process

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR016040

P

Seeded from EcoCyc [5]

complete

GO:0055114

oxidation reduction

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0560

P

Seeded from EcoCyc [5]

complete

GO:0019395

fatty acid oxidation

P

Seeded from EcoCyc 11.1[3].

required fields missing

GO:0005515

protein binding

PMID:16782065[7]

IDA: Inferred from Direct Assay

C

complete

GO:0008774

acetaldehyde dehydrogenase (acetylating) activity

PMID:9098055[8]

IDA: Inferred from Direct Assay

F

complete

Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type Partner Notes References Evidence

Protein

dnaK

PMID:16606699[9]

Experiment(s):EBI-1136338

Protein

glpD

PMID:16606699[9]

Experiment(s):EBI-1136338

Protein

nadE

PMID:16606699[9]

Experiment(s):EBI-1136338


Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

Compartment Description Evidence Source Notes


Notes

Structure and Physical Properties

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Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Sequence

at EcoCyc

MSKRKVAIIG SGNIGTDLMI KILRHGQHLE MAVMVGIDPQ SDGLARARRM GVATTHEGVI
GLMNMPEFAD IDIVFDATSA GAHVKNDAAL REAKPDIRLI DLTPAAIGPY CVPVVNLEAN
VDQLNVNMVT CGGQATIPMV AAVSRVARVH YAEIIASIAS KSAGPGTRAN IDEFTETTSR
AIEVVGGAAK GKAIIVLNPA EPPLMMRDTV YVLSDEASQD DIEASINEMA EAVQAYVPGY
RLKQRVQFEV IPQDKPVNLP GVGQFSGLKT AVWLEVEGAA HYLPAYAGNL DIMTSSALAT
AEKMAQSLAR KAGEAA
Length

316

Mol. Wt

33.442 kDa

pI

5.3 (calculated)

Extinction coefficient

15,930 - 16,180 (calc based on 7 Y, 1 W, and 2 C residues)


Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Type Residues Description Notes References

<motif_map/>

Structure
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

<beststructure> gene=mhpF taxon=562,83333 </beststructure>

Models

View models at:

Structure figures

Notes

Gene Product Resources

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See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type Source Notes/Reference


Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

EcoCyc (EcoliWiki Page)

EcoCyc:MHPF-MONOMER

SwissModel (EcoliWiki Page)

SwissModel:P77580

UniProt (EcoliWiki Page)

UniProt:P77580

PFAM (EcoliWiki Page)

PFAM:PF02396

RefSeq (EcoliWiki Page)

RefSeq:NP_414885



Notes

Links

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References

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See Help:References for how to manage references in EcoliWiki.

  1. ↑ 1.0 1.1 1.2 1.3 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  5. ↑ 5.0 5.1 5.2 5.3 5.4 5.5 5.6 5.7 5.8 EcoCyc (release 13.0; 2009) Keseler, IM et al. (2009) Nucleic Acids Res. 37(Database issue):D464-70
  6. ↑ 6.0 6.1 EcoCyc (release 12.5; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  7. ↑ Lee, SJ et al. (2006) Coupled expression of MhpE aldolase and MhpF dehydrogenase in Escherichia coli. Biochem. Biophys. Res. Commun. 346 1009-15 PubMed
  8. ↑ Ferrández, A et al. (1997) Genetic characterization and expression in heterologous hosts of the 3-(3-hydroxyphenyl)propionate catabolic pathway of Escherichia coli K-12. J. Bacteriol. 179 2573-81 PubMed
  9. ↑ 9.0 9.1 9.2 Arifuzzaman, M et al. (2006) Large-scale identification of protein-protein interaction of Escherichia coli K-12. Genome Res. 16 686-91 PubMed

Categories

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