lpxM:Gene Product(s): Difference between revisions

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|-
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!align=left |Standard name
!align=left {{table heading style}} |Standard name
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LpxM  
LpxM  
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!align=left |Synonyms
!align=left {{table heading style}} |Synonyms
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myristoyl-acyl carrier protein (ACP)-dependent acyltransferase<ref name='LIB:Riley_2006'/>, B1855<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, WaaN<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, Mlt<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, LpxM<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, MsbB<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>  
myristoyl-acyl carrier protein (ACP)-dependent acyltransferase<ref name='LIB:Riley_2006'/>, B1855<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, WaaN<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, Mlt<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, LpxM<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, MsbB<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>  
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!align=left |Product description
!align=left {{table heading style}} |Product description
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Lipid A biosynthesis; KDO2-lauroyl-lipid IVA myristoyl-ACP acyltransferase<ref name='LIB:EcoGene'/>
Lipid A biosynthesis; KDO2-lauroyl-lipid IVA myristoyl-ACP acyltransferase<ref name='LIB:EcoGene'/>
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!align=left |EC number (for enzymes)
!align=left {{table heading style}} |EC number (for enzymes)
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* [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.1.- 2.3.1.-]<ref name='LIB:Riley_2006'/>
* [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.1.- 2.3.1.-]<ref name='LIB:Riley_2006'/>
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{|  id="P46aa820cc8586"  class=" tableEdit GO_table_product dataTable"   
{|  id="P46aa820cc8586"  class=" tableEdit GO_table_product dataTable"   
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|- {{table_heading_style}}
!|Qualifier!!GO ID!!GO term name!!Reference(s)!!Evidence Code!!with/from!!Aspect!!Notes!!Status
!|Qualifier!!GO ID!!GO term name!!Reference(s)!!Evidence Code!!with/from!!Aspect!!Notes!!Status
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!|Partner Type!!Partner!!Notes!!References!!Evidence
!|Partner Type!!Partner!!Notes!!References!!Evidence
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{|  id="R46aa82172ca5f"  class=" tableEdit Product_localization_table"   
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!|Compartment!!Description!!Evidence!!Source!!Notes
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|-
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!align=left |Sequence
!align=left {{table heading style}} |Sequence
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[http://biocyc.org/ECOLI/sequence-aa?object=MYRISTOYLACYLTRAN-MONOMER at EcoCyc]  
[http://biocyc.org/ECOLI/sequence-aa?object=MYRISTOYLACYLTRAN-MONOMER at EcoCyc]  
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KLLKTRKPGE IQPYKRKDLY PIK</pre>  
KLLKTRKPGE IQPYKRKDLY PIK</pre>  
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!align=left |Length
!align=left {{table heading style}} |Length
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323
323
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!align=left |Mol. Wt
!align=left {{table heading style}} |Mol. Wt
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37.411 kDa
37.411 kDa
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!align=left |pI
!align=left {{table heading style}} |pI
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10.0 (calculated)
10.0 (calculated)
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!align=left |Extinction coefficient
!align=left {{table heading style}} |Extinction coefficient
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54,890 - 55,140 (calc based on 11 Y, 7 W, and 2 C residues)
54,890 - 55,140 (calc based on 11 Y, 7 W, and 2 C residues)
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{|  id="Z46aa8219315eb"  class=" tableEdit Product_motif_table"   
{|  id="Z46aa8219315eb"  class=" tableEdit Product_motif_table dataTable"   
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!|Type!!Residues!!Description!!Notes
!|Type!!Residues!!Description!!Notes!!References


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|-
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!align=left |Structures
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<beststructure>
<beststructure>
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</beststructure>
</beststructure>
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!align=left |Models
!align=left {{table heading style}} |Models
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View models at:
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{|  id="Y46aa8219e9c96"  class=" tableEdit Product_resource_table"   
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!|Resource type!!Source!!Notes/Reference
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!|Database!!Accession!!Notes
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!|Name!!URL!!Comments
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Revision as of 20:21, 23 February 2010

{{#css:Suppresslinks.css}}<css>h1 .editsection { display:none;} h2 .editsection { display:none;}</css>

Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.

Standard name

LpxM

Synonyms

myristoyl-acyl carrier protein (ACP)-dependent acyltransferase[1], B1855[2][1], WaaN[2][1], Mlt[2][1], LpxM[2][1], MsbB[2][1]

Product description

Lipid A biosynthesis; KDO2-lauroyl-lipid IVA myristoyl-ACP acyltransferase[3]

EC number (for enzymes)
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Notes

Function

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Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference(s) Evidence Code with/from Aspect Notes Status
GO:0016747

transferase activity, transferring acyl groups other than amino-acyl groups

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR011921

F

Seeded from EcoCyc [4]

complete

GO:0016740

transferase activity

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0808

F

Seeded from EcoCyc [4]

complete

GO:0016021

integral to membrane

GO_REF:0000002
GO_REF:0000002
GO_REF:0000004

IEA: Inferred from Electronic Annotation

InterPro:IPR004960
InterPro:IPR011921
SP_KW:KW-0812

C

Seeded from EcoCyc [4]

complete

GO:0016020

membrane

GO_REF:0000004
GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0397
SP_KW:KW-0472

C

Seeded from EcoCyc 12.5 [5]

complete

GO:0009276

Gram-negative-bacterium-type cell wall

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR011921

C

Seeded from EcoCyc [4]

complete

GO:0009244

lipopolysaccharide core region biosynthetic process

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR004960

P

Seeded from EcoCyc [4]

complete

GO:0009103

lipopolysaccharide biosynthetic process

GO_REF:0000002
GO_REF:0000004

IEA: Inferred from Electronic Annotation

InterPro:IPR011921
SP_KW:KW-0448

P

Seeded from EcoCyc [4]

complete

GO:0008415

acyltransferase activity

GO_REF:0000002
GO_REF:0000004

IEA: Inferred from Electronic Annotation

InterPro:IPR004960
SP_KW:KW-0012

F

Seeded from EcoCyc [4]

complete

GO:0031225

anchored to membrane

C

Seeded from Riley et al 2006 [1].

required fields missing

GO:0005886

plasma membrane

GO_REF:0000004
GO_REF:0000004
GO_REF:0000023

IEA: Inferred from Electronic Annotation

SP_KW:KW-0997
SP_KW:KW-1003
SP_SL:SL-0037

C

Seeded from EcoCyc [4]

complete

GO:0009245

lipid A biosynthetic process

P

Seeded from EcoCyc 11.1[6].

required fields missing

GO:0042280

cell surface antigen activity, host-interacting

F

Seeded from Riley et al 2006 [1].

required fields missing

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Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type Partner Notes References Evidence

Protein

groL

PMID:16606699[7]

Experiment(s):EBI-1141045

Protein

alaS

PMID:16606699[7]

Experiment(s):EBI-1141045

Protein

glpD

PMID:16606699[7]

Experiment(s):EBI-1141045

Protein

ymfG

PMID:16606699[7]

Experiment(s):EBI-1141045

Protein

relE

PMID:16606699[7]

Experiment(s):EBI-1141045

Protein

ahpF

PMID:16606699[7]

Experiment(s):EBI-1141045

Protein

fusA

PMID:16606699[7]

Experiment(s):EBI-1141045

Protein

rpsM

PMID:16606699[7]

Experiment(s):EBI-1141045

Protein

recB

PMID:16606699[7]

Experiment(s):EBI-1141045

Protein

aceE

PMID:16606699[7]

Experiment(s):EBI-1141045

Protein

zwf

PMID:16606699[7]

Experiment(s):EBI-1141045

Protein

gyrA

PMID:16606699[7]

Experiment(s):EBI-1141045

Protein

clpB

PMID:16606699[7]

Experiment(s):EBI-1141045

Protein

glnD

PMID:16606699[7]

Experiment(s):EBI-1141045

Protein

htrB

PMID:16606699[7]

Experiment(s):EBI-1141045

Protein

acnB

PMID:16606699[7]

Experiment(s):EBI-1141045

Protein

ymfM

PMID:16606699[7]

Experiment(s):EBI-1141045

Protein

nuoG

PMID:16606699[7]

Experiment(s):EBI-1141045

Protein

topA

PMID:16606699[7]

Experiment(s):EBI-1141045

Protein

fliY

PMID:16606699[7]

Experiment(s):EBI-1141045
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Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

Compartment Description Evidence Source Notes

plasma membrane

From EcoCyc[6]


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Notes

Structure and Physical Properties

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Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Sequence

at EcoCyc 

METKKNNSEY IPEFDKSFRH PRYWGAWLGV AAMAGIALTP PKFRDPILAR LGRFAGRLGK
SSRRRALINL SLCFPERSEA EREAIVDEMF ATAPQAMAMM AELAIRGPEK IQPRVDWQGL
EIIEEMRRNN EKVIFLVPHG WAVDIPAMLM ASQGQKMAAM FHNQGNPVFD YVWNTVRRRF
GGRLHARNDG IKPFIQSVRQ GYWGYYLPDQ DHGPEHSEFV DFFATYKATL PAIGRLMKVC
RARVVPLFPI YDGKTHRLTI QVRPPMDDLL EADDHTIARR MNEEVEIFVG PRPEQYTWIL
KLLKTRKPGE IQPYKRKDLY PIK
Length

323

Mol. Wt

37.411 kDa

pI

10.0 (calculated)

Extinction coefficient

54,890 - 55,140 (calc based on 11 Y, 7 W, and 2 C residues)

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Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Type Residues Description Notes References
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<motif_map/>

Structure
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

<beststructure> gene=lpxM taxon=562,83333 </beststructure>

Models

View models at:

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Structure figures

Notes

Gene Product Resources

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See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type Source Notes/Reference
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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

EcoCyc (EcoliWiki Page)

EcoCyc:MYRISTOYLACYLTRAN-MONOMER

UniProt (EcoliWiki Page)

UniProt:P24205

PFAM (EcoliWiki Page)

PFAM:PF03279

RefSeq (EcoliWiki Page)

RefSeq:NP_416369


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Notes

Links

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References

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See Help:References for how to manage references in EcoliWiki.

  1. ↑ 1.0 1.1 1.2 1.3 1.4 1.5 1.6 1.7 1.8 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 2.4 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  4. ↑ 4.0 4.1 4.2 4.3 4.4 4.5 4.6 4.7 EcoCyc (release 13.0; 2009) Keseler, IM et al. (2009) Nucleic Acids Res. 37(Database issue):D464-70
  5. ↑ EcoCyc (release 12.5; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  6. ↑ 6.0 6.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  7. ↑ 7.00 7.01 7.02 7.03 7.04 7.05 7.06 7.07 7.08 7.09 7.10 7.11 7.12 7.13 7.14 7.15 7.16 7.17 7.18 7.19 Arifuzzaman, M et al. (2006) Large-scale identification of protein-protein interaction of Escherichia coli K-12. Genome Res. 16 686-91 PubMed

Categories

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