hsdR:Gene Product(s): Difference between revisions

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!align=left |Standard name
!align=left {{table heading style}} |Standard name
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HsdR product  
HsdR product  
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!align=left |Synonyms
!align=left {{table heading style}} |Synonyms
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endonuclease R product<ref name='LIB:Riley_2006'/>, B4350 product<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, Hsr product<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, Hsp product<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, HsdR product<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>  
endonuclease R product<ref name='LIB:Riley_2006'/>, B4350 product<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, Hsr product<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, Hsp product<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, HsdR product<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>  
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!align=left |Product description
!align=left {{table heading style}} |Product description
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host restriction; endonuclease R<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>;  
host restriction; endonuclease R<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>;  
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Endonuclease R, host restriction of foreign DNA; ClpXP-dependent degradation<ref name='LIB:EcoGene'/>
Endonuclease R, host restriction of foreign DNA; ClpXP-dependent degradation<ref name='LIB:EcoGene'/>
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!align=left |EC number (for enzymes)
!align=left {{table heading style}} |EC number (for enzymes)
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* [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.21.3 3.1.21.3]<ref name='LIB:Riley_2006'/>
* [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.21.3 3.1.21.3]<ref name='LIB:Riley_2006'/>
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****************************************************************************************** -->{{Product_GO_help}}
****************************************************************************************** -->{{Product_GO_help}}
{|  id="A46ab2e941f9fb"  class=" tableEdit GO_table_product dataTable"   
{|  id="A46ab2e941f9fb"  class=" tableEdit GO_table_product dataTable"   
|-
|- {{table_heading_style}}
!|Qualifier!!GO ID!!GO term name!!Reference(s)!!Evidence Code!!with/from!!Aspect!!Notes!!Status
!|Qualifier!!GO ID!!GO term name!!Reference(s)!!Evidence Code!!with/from!!Aspect!!Notes!!Status
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|-  
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*  
*  
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{|  id="K46ab2ea8d5e06"  class=" tableEdit Product_interactions_table"   
{|  id="K46ab2ea8d5e06"  class=" tableEdit Product_interactions_table dataTable"   
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!|Partner Type!!Partner!!Notes!!References!!Evidence
!|Partner Type!!Partner!!Notes!!References!!Evidence
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{|  id="Q46ab2eaa35081"  class=" tableEdit Product_localization_table"   
{|  id="Q46ab2eaa35081"  class=" tableEdit Product_localization_table"   
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!|Compartment!!Description!!Evidence!!Source!!Notes
!|Compartment!!Description!!Evidence!!Source!!Notes


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|-
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!align=left |Sequence
!align=left {{table heading style}} |Sequence
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[http://biocyc.org/ECOLI/sequence-aa?object=EG10459-MONOMER at EcoCyc]  
[http://biocyc.org/ECOLI/sequence-aa?object=EG10459-MONOMER at EcoCyc]  
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EKVVLDDDVF KTGNFHRRGG KAMLQRTFDD NLDTLLGKFS DYIWDELA</pre>  
EKVVLDDDVF KTGNFHRRGG KAMLQRTFDD NLDTLLGKFS DYIWDELA</pre>  
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!align=left |Length
!align=left {{table heading style}} |Length
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1,188
1,188
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!align=left |Mol. Wt
!align=left {{table heading style}} |Mol. Wt
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136.103 kDa
136.103 kDa
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!align=left |pI
!align=left {{table heading style}} |pI
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5.9 (calculated)
5.9 (calculated)
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!align=left |Extinction coefficient
!align=left {{table heading style}} |Extinction coefficient
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134,650 - 136,150 (calc based on 35 Y, 15 W, and 12 C residues)
134,650 - 136,150 (calc based on 35 Y, 15 W, and 12 C residues)
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*  
*  
****************************************************************************************** -->{{Product_domains_motifs_help}}
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{|  id="J46ab2eaca49a2"  class=" tableEdit Product_motif_table"   
{|  id="J46ab2eaca49a2"  class=" tableEdit Product_motif_table dataTable"   
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|- {{table heading style}}
!|Type!!Residues!!Description!!Notes
!|Type!!Residues!!Description!!Notes!!References


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|-
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!align=left |Structures
!align=left {{table heading style}} |Structures
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<beststructure>
<beststructure>
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</beststructure>
</beststructure>
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!align=left |Models
!align=left {{table heading style}} |Models
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View models at:
View models at:
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{|  id="H46ab2ead82529"  class=" tableEdit Product_resource_table"   
{|  id="H46ab2ead82529"  class=" tableEdit Product_resource_table"   
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!|Resource type!!Source!!Notes/Reference
!|Resource type!!Source!!Notes/Reference


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{|  id="H46ab2eadeb887"  class=" tableEdit Gene_accessions_table"   
{|  id="H46ab2eadeb887"  class=" tableEdit Gene_accessions_table"   
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!|Database!!Accession!!Notes
!|Database!!Accession!!Notes
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{|  id="J46ab2eb27be05"  class=" tableEdit Links_table"   
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!|Name!!URL!!Comments
!|Name!!URL!!Comments


Revision as of 20:08, 23 February 2010

{{#css:Suppresslinks.css}}<css>h1 .editsection { display:none;} h2 .editsection { display:none;}</css>

Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.

Standard name

HsdR product

Synonyms

endonuclease R product[1], B4350 product[2][1], Hsr product[2][1], Hsp product[2][1], HsdR product[2][1]

Product description

host restriction; endonuclease R[2][3];

Component of [[:Category:Complex:EcoKI restriction-modification system|EcoKI restriction-modification system]][3]

Endonuclease R, host restriction of foreign DNA; ClpXP-dependent degradation[4]

EC number (for enzymes)
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Notes

Function

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Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference(s) Evidence Code with/from Aspect Notes Status
GO:0000166

nucleotide binding

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0547

F

Seeded from EcoCyc [5]

complete

GO:0003676

nucleic acid binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001650

F

Seeded from EcoCyc [5]

complete

GO:0003677

DNA binding

GO_REF:0000002
GO_REF:0000002
GO_REF:0000004

IEA: Inferred from Electronic Annotation

InterPro:IPR006935
InterPro:IPR007409
SP_KW:KW-0238

F

Seeded from EcoCyc [5]

complete

GO:0004386

helicase activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001650

F

Seeded from EcoCyc [5]

complete

GO:0004519

endonuclease activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR007409

F

Seeded from EcoCyc [5]

complete

GO:0005524

ATP binding

GO_REF:0000002
GO_REF:0000002
GO_REF:0000004

IEA: Inferred from Electronic Annotation

InterPro:IPR001650
InterPro:IPR006935
SP_KW:KW-0067

F

Seeded from EcoCyc [5]

complete

GO:0006304

DNA modification

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR007409

P

Seeded from EcoCyc [5]

complete

GO:0009035

Type I site-specific deoxyribonuclease activity

GO_REF:0000003

IEA: Inferred from Electronic Annotation

EC:3.1.21.3

F

Seeded from EcoCyc [5]

complete

GO:0009307

DNA restriction-modification system

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0680

P

Seeded from EcoCyc [5]

complete

GO:0016787

hydrolase activity

GO_REF:0000002
GO_REF:0000004

IEA: Inferred from Electronic Annotation

InterPro:IPR006935
SP_KW:KW-0378

F

Seeded from EcoCyc [5]

complete

GO:0005737

cytoplasm

C

Seeded from EcoCyc 11.1[3].

required fields missing

GO:0006308

DNA catabolic process

P

Seeded from EcoCyc 11.1[3].

required fields missing

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Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type Partner Notes References Evidence

Protein

Subunits of [[:Category:Complex:EcoKI restriction-modification system|EcoKI restriction-modification system]]

could be indirect

Protein

aceF

PMID:15690043[6]

Experiment(s):EBI-889458, EBI-894477

Protein

hsdM

PMID:15690043[6]

Experiment(s):EBI-889458, EBI-890115, EBI-894477, EBI-895107

Protein

lpdA

PMID:15690043[6]

Experiment(s):EBI-889458, EBI-894477

Protein

rplL

PMID:15690043[6]

Experiment(s):EBI-894477
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Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

Compartment Description Evidence Source Notes
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Notes

Structure and Physical Properties

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Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Sequence

at EcoCyc 

MLWALNIWTG PHSNGLITMM NKSNFEFLKG VNDFTYAIAC AAENNYPDDP NTTLIKMRMF
GEATAKHLGL LLNIPPCENQ HDLLRELGKI AFVDDNILSV FHKLRRIGNQ AVHEYHNDLN
DAQMCLRLGF RLAVWYYRLV TKDYDFPVPV FVLPERGENL YHQEVLTLKQ QLEQQVREKA
QTQAEVEAQQ QKLVALNGYI AILEGKQQET EAQTQARLAA LEAQLAEKNA ELAKQTEQER
KAYHKEITDQ AIKRTLNLSE EESRFLIDAQ LRKAGWQADS KTLRFSKGAR PEPGVNKAIA
EWPTGKDETG NQGFADYVLF VGLKPIAVVE AKRNNIDVPA RLNESYRYSK CFDNGFLRET
LLEHYSPDEV HEAVPEYETS WQDTSGKQRF KIPFCYSTNG REYRATMKTK SGIWYRDVRD
TRNMSKALPE WHRPEELLEM LGSEPQKQNQ WFADNPGMSE LGLRYYQEDA VRAVEKAIVK
GQQEILLAMA TGTGKTRTAI AMMFRLIQSQ RFKRILFLVD RRSLGEQALG AFEDTRINGD
TFNSIFDIKG LTDKFPEDST KIHVATVQSL VKRTLQSDEP MPVARYDCIV VDEAHRGYIL
DKEQTEGELQ FRSQLDYVSA YRRILDHFDA VKIALTATPA LHTVQIFGEP VYRYTYRTAV
IDGFLIDQDP PIQIITRNAQ EGVYLSKGEQ VERISPQGEV INDTLEDDQD FEVADFNRGL
VIPAFNRAVC NELTNYLDPT GSQKTLVFCV TNAHADMVVE ELRAAFKKKY PQLEHDAIIK
ITGDADKDAR KVQTMITRFN KERLPNIVVT VDLLTTGVDI PSICNIVFLR KVRSRILYEQ
MKGRATRLCP EVNKTSFKIF DCVDIYSTLE SVDTMRPVVV RPKVELQTLV NEITDSETYK
ITEADGRSFA EHSHEQLVAK LQRIIGLATF NRDRSETIDK QVRRLDELCQ DAAGVNFNGF
ASRLREKGPH WSAEVFNKLP GFIARLEKLK TDINNLNDAP IFLDIDDEVV SVKSLYGDYD
TPQDFLEAFD SLVQRSPNAQ PALQAVINRP RDLTRKGLVE LQEWFDRQHF EESSLRKAWK
ETRNEDIAAR LIGHIRRAAV GDALKPFEER VDHALTRIKG ENDWSSEQLS WLDRLAQALK
EKVVLDDDVF KTGNFHRRGG KAMLQRTFDD NLDTLLGKFS DYIWDELA
Length

1,188

Mol. Wt

136.103 kDa

pI

5.9 (calculated)

Extinction coefficient

134,650 - 136,150 (calc based on 35 Y, 15 W, and 12 C residues)

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Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Type Residues Description Notes References
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<motif_map/>

Structure
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

<beststructure> gene=hsdR taxon=562,83333 </beststructure>

Models

View models at:

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Structure figures

Notes

Gene Product Resources

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See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type Source Notes/Reference
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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

EcoCyc (EcoliWiki Page)

EcoCyc:EG10459-MONOMER

UniProt (EcoliWiki Page)

UniProt:P08956

PFAM (EcoliWiki Page)

PFAM:PF04313

RefSeq (EcoliWiki Page)

RefSeq:NP_418770

ECOO157CYC (EcoliWiki Page)

ECOO157CYC:Z5948-MONOMER


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Notes

Links

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References

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See Help:References for how to manage references in EcoliWiki.

  1. ↑ 1.0 1.1 1.2 1.3 1.4 1.5 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 2.4 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ 3.0 3.1 3.2 3.3 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  5. ↑ 5.00 5.01 5.02 5.03 5.04 5.05 5.06 5.07 5.08 5.09 EcoCyc (release 13.0; 2009) Keseler, IM et al. (2009) Nucleic Acids Res. 37(Database issue):D464-70
  6. ↑ 6.0 6.1 6.2 6.3 Butland, G et al. (2005) Interaction network containing conserved and essential protein complexes in Escherichia coli. Nature 433 531-7 PubMed

Categories

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[[Category:Complex:EcoKI restriction-modification system]]

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