putA:Quickview: Difference between revisions

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!align=left |Standard Name
!align=left {{table_heading_style}} |Standard Name
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''putA''  
''putA''  
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!align=left |Gene Synonym(s)
!align=left {{table_heading_style}} |Gene Synonym(s)
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''ECK1005, b1014, JW0999, poaA, putC, proline utilization A''<ref name='LIB:Riley_2006'/><ref name='LIB:EcoCyc10.6'/>
''ECK1005, b1014, JW0999, poaA, putC, proline utilization A''<ref name='LIB:Riley_2006'/><ref name='LIB:EcoCyc10.6'/>
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!align=left |Product Desc.
!align=left {{table_heading_style}} |Product Desc.
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PutA bifunctional enzyme and transcriptional regulator<ref name='LIB:EcoCyc10.6'/>; PutA transcriptional repressor, Proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase<ref name='LIB:EcoCyc11.1'/>;  
PutA bifunctional enzyme and transcriptional regulator<ref name='LIB:EcoCyc10.6'/>; PutA transcriptional repressor, Proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase<ref name='LIB:EcoCyc11.1'/>;  
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Proline dehydrogenase and repressor for the putAP divergon<ref name='LIB:EcoGene'/>
Proline dehydrogenase and repressor for the putAP divergon<ref name='LIB:EcoGene'/>
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!align=left |Product Synonyms(s)
!align=left {{table_heading_style}} |Product Synonyms(s)
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fused DNA-binding transcriptional regulator<ref name='LIB:Riley_2006'/>, proline dehydrogenase<ref name='LIB:Riley_2006'/>, pyrroline-5-carboxylate dehydrogenase<ref name='LIB:Riley_2006'/>, B1014<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, PutC<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, PoaA<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, PutA<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>  
fused DNA-binding transcriptional regulator<ref name='LIB:Riley_2006'/>, proline dehydrogenase<ref name='LIB:Riley_2006'/>, pyrroline-5-carboxylate dehydrogenase<ref name='LIB:Riley_2006'/>, B1014<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, PutC<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, PoaA<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, PutA<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>  
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!align=left |Knock-Out Phenotype
!align=left {{table_heading_style}} |Function from GO
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'''Molecular Function'''
* GO:0005515 protein binding ([http://www.geneontology.org/GO.evidence.shtml IPI])


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!align=left |Regulation/Expression
!align=left {{table_heading_style}} |Knock-Out Phenotype
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!align=left {{table_heading_style}} |Regulation/Expression
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transcription unit(s): [[:Category:Txn_unit:putA|putA]]<ref name='LIB:EcoCyc10.6'/>  
transcription unit(s): [[:Category:Txn_unit:putA|putA]]<ref name='LIB:EcoCyc10.6'/>  
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!align=left |Regulation/Activity
!align=left {{table_heading_style}} |Regulation/Activity
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!align=left {{table_heading_style}} |Quick Links
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[http://ecoliwiki.net/tools/display_dna.php?gene=putA&loc=MG1655:1078105..1074143,W3110:1079304..1075342,DH10B:1132033..1128071,REL606:1095166..1091204 DNA display]&nbsp;&nbsp;&nbsp; [http://ecoliwiki.net/tools/display_protein.php?f=NC_000913&start=1095166&end=1091204&gene=putA&aa=mgtttmgvklddatreriksaatridrtphwlikqaifsyleqlensdtlpelpallsgaanesdeaptpaeephqpfldfaeqilpqsvsraaitaayrrpeteavsmlleqarlpqpvaeqahklayqladklrnqknasgragmvqgllqefslssqegvalmclaeallripdkatrdalirdkisngnwqshigrspslfvnaatwgllftgklvsthneaslsrslnriigksgeplirkgvdmamrlmgeqfvtgetiaealanarkleekgfrysydmlgeaaltaadaqaymvsyqqaihaigkasngrgiyegpgisiklsalhprysraqydrvmeelyprlksltllarqydiginidaeesdrleisldlleklcfepelagwngigfviqayqkrcplvidylidlatrsrrrlmirlvkgaywdseikraqmdglegypvytrkvytdvsylacakkllavpnliypqfathnahtlaaiyqlagqnyypgqyefqclhgmgeplyeqvtgkvadgklnrpcriyapvgthetllaylvrrllengantsfvnriadtslpldelvadpvtaveklaqqegqtglphpkiplprdlyghgrdnsagldlanehrlaslssallnsalqkwqalpmleqpvaagemspvinpaepkdivgyvreatpreveqalesavnnapiwfatppaeraailhraavlmesqmqqligilvreagktfsnaiaevreavdflhyyagqvrddfanethrplgpvvcispwnfplaiftgqiaaalaagnsvlakpaeqtpliaaqgiailleagvppgvvqllpgrgetvgaqltgddrvrgvmftgstevatllqrniasrldaqgrpipliaetggmnamivdssalteqvvvdvlasafdsagqrcsalrvlclqdeiadhtlkmlrgamaecrmgnpgrlttdigpvidseakanierhiqtmrskgrpvfqavrensedarewqsgtfvaptlielddfaelqkevfgpvlhvvrynrnqlpelieqinasgygltlgvhtridetiaqvtgsahvgnlyvnrnmvgavvgvqpfggeglsgtgpkaggplylyrllanrpesalavtlarqdakypvdaqlkaaltqplnalrewaanrpelqalctqygelaqagtqrllpgptgerntwtllprervlciaddeqdaltqlaavlavgsqvlwpddalhrqlvkalpsavseriqlakaenitaqpfdavifhgdsdqlralceavaardgtivsvqgfargesnillerlyierslsvntaaaggnaslmtig Protein display]&nbsp;&nbsp;&nbsp; [http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=Search&Term=putA+AND+escherichia+coli Pubmed(putA)]&nbsp;&nbsp;&nbsp; [http://trimer.tamu.edu/cgi-bin/textpresso/2.1/ecoli/search?searchstring=putA Textpresso(putA)]


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Revision as of 00:21, 22 January 2010

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions

See Help:Quickview for help with entering information in the Quickview table.

Standard Name

putA

Gene Synonym(s)

ECK1005, b1014, JW0999, poaA, putC, proline utilization A[1][2]

Product Desc.

PutA bifunctional enzyme and transcriptional regulator[2]; PutA transcriptional repressor, Proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase[3];

Component of PUTA-CPLX[2]; PutA transcriptional repressor, Proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase[3]

Proline dehydrogenase and repressor for the putAP divergon[4]

Product Synonyms(s)

fused DNA-binding transcriptional regulator[1], proline dehydrogenase[1], pyrroline-5-carboxylate dehydrogenase[1], B1014[2][1], PutC[2][1], PoaA[2][1], PutA[2][1]

Function from GO

Molecular Function

Knock-Out Phenotype
Regulation/Expression

transcription unit(s): putA[2]

Regulation/Activity
Quick Links

DNA display    Protein display    Pubmed(putA)    Textpresso(putA)

edit table

See Help:Quickview for help with entering information in the Quickview table.

Notes

[back to top]


PutA is a multifunctional membrane-associated flavoprotein involved in proline catabolism: the central proline dehydrogenese domain feeds its product to the C-terminal Delta(1)-pyrroline-5-carboxylate dehydrogenese domain, to produce glutamate. The N-terminal 90 residue domain is the DNA-binding repressor domain. A divergon is a regulon comprised of two adjacent divergent operons or genes. Binds TrxA (Kumar, 2004).[4]



References

[back to top]


  1. ↑ 1.0 1.1 1.2 1.3 1.4 1.5 1.6 1.7 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 2.4 2.5 2.6 2.7 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
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