Phage lambda cI:Gene Product(s): Difference between revisions

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|-
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!align=left |Standard name
!align=left {{table heading style}} |Standard name
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cI  
cI  
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!align=left |Synonyms
!align=left {{table heading style}} |Synonyms
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cI, lambdap88  
cI, lambdap88  
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!align=left |Product description
!align=left {{table heading style}} |Product description
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repressor  
repressor  
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!align=left |EC number (for enzymes)
!align=left {{table heading style}} |EC number (for enzymes)
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****************************************************************************************** -->{{Product_GO_help}}
****************************************************************************************** -->{{Product_GO_help}}
{|  class=" tableEdit GO_table_product dataTable"   
{|  class=" tableEdit GO_table_product dataTable"   
|-
|- {{table_heading_style}}
!|Qualifier!!GO ID!!GO term name!!Reference(s)!!Evidence Code!!with/from!!Aspect!!Notes!!Status
!|Qualifier!!GO ID!!GO term name!!Reference(s)!!Evidence Code!!with/from!!Aspect!!Notes!!Status


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*  
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****************************************************************************************** -->{{Product_interactions_help}}
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{|  id="D4a848f7275feb"  class=" tableEdit Product_interactions_table"   
{|  id="D4a848f7275feb"  class=" tableEdit Product_interactions_table dataTable"   
|-
|- {{table heading style}}
!|Partner Type!!Partner!!Notes!!References!!Evidence
!|Partner Type!!Partner!!Notes!!References!!Evidence


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****************************************************************************************** -->{{Product_localization_help}}
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{|  class=" tableEdit Product_localization_table"   
{|  class=" tableEdit Product_localization_table"   
|-
|- {{table heading style}}
!|Compartment!!Description!!Evidence!!Source!!Notes
!|Compartment!!Description!!Evidence!!Source!!Notes


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|-
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!align=left |Sequence
!align=left {{table heading style}} |Sequence
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CIARLGGDEF TFKKLIRDSG QVFLQPLNPQ YPMIPCNESC SVVGKVIASQ WPEETFG</pre>  
CIARLGGDEF TFKKLIRDSG QVFLQPLNPQ YPMIPCNESC SVVGKVIASQ WPEETFG</pre>  
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!align=left |Length
!align=left {{table heading style}} |Length
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237
237
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!align=left |Mol. Wt
!align=left {{table heading style}} |Mol. Wt
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26.211 kDa
26.211 kDa
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!align=left |pI
!align=left {{table heading style}} |pI
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4.9 (calculated)
4.9 (calculated)
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|-
!align=left |Extinction coefficient
!align=left {{table heading style}} |Extinction coefficient
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26,930 - 27,305 (calc based on 7 Y, 3 W, and 3 C residues)
26,930 - 27,305 (calc based on 7 Y, 3 W, and 3 C residues)
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****************************************************************************************** -->{{Product_domains_motifs_help}}
****************************************************************************************** -->{{Product_domains_motifs_help}}
{|  class=" tableEdit Product_motif_table"   
{|  class=" tableEdit Product_motif_table dataTable"   
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|- {{table heading style}}
!|Type!!Residues!!Description!!Notes
!|Type!!Residues!!Description!!Notes!!References
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[[interpro:IPR000655|HTH cro/C1-type]]
[[interpro:IPR000655|HTH cro/C1-type]]
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[http://www.uniprot.org/uniprot/P03034#section_features UniProt:P03034]  
[http://www.uniprot.org/uniprot/P03034#section_features UniProt:P03034]
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|<span class="tableEdit_editLink plainlinks">[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79..D46a403a8088eb&page=104187&pagename={{FULLPAGENAMEE}}&type=&template=Product_motif_table edit table]</span> || || || ||
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{|  class=" tableEdit Product_structure_table"   
{|{{Prettytable}} class=" tableEdit Product_structure_table"   


|-
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!align=left |Structures
!align=left {{table heading style}} |Structures
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<beststructure>
<beststructure>
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</beststructure>
</beststructure>
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!align=left |Models
!align=left {{table heading style}} |Models
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View models at:
View models at:
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****************************************************************************************** -->{{Product_resources_help}}
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{|  class=" tableEdit Product_resource_table"   
{|  class=" tableEdit Product_resource_table"   
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!|Resource type!!Source!!Notes/Reference
!|Resource type!!Source!!Notes/Reference


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****************************************************************************************** -->{{Gene_accessions_help}}
****************************************************************************************** -->{{Gene_accessions_help}}
{|  class=" tableEdit Gene_accessions_table"   
{|  class=" tableEdit Gene_accessions_table"   
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|- {{table_heading_style}}
!|Database!!Accession!!Notes
!|Database!!Accession!!Notes
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{|  class=" tableEdit Links_table"   
{|  class=" tableEdit Links_table"   
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!|Name!!URL!!Comments
!|Name!!URL!!Comments


Revision as of 20:42, 23 February 2010

{{#css:Suppresslinks.css}}<css>h1 .editsection { display:none;} h2 .editsection { display:none;}</css>

Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.

Standard name

cI

Synonyms

cI, lambdap88

Product description

repressor

EC number (for enzymes)


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Notes

Function

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Gene Ontology See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference(s) Evidence Code with/from Aspect Notes Status
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Interactions <protect> See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type Partner Notes References Evidence
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Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

Compartment Description Evidence Source Notes
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Notes

Structure and Physical Properties

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Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Sequence 
MSTKKKPLTQ EQLEDARRLK AIYEKKKNEL GLSQESVADK MGMGQSGVGA LFNGINALNA
YNAALLAKIL KVSVEEFSPS IAREIYEMYE AVSMQPSLRS EYEYPVFSHV QAGMFSPELR
TFTKGDAERW VSTTKKASDS AFWLEVEGNS MTAPTGSKPS FPDGMLILVD PEQAVEPGDF
CIARLGGDEF TFKKLIRDSG QVFLQPLNPQ YPMIPCNESC SVVGKVIASQ WPEETFG
Length

237

Mol. Wt

26.211 kDa

pI

4.9 (calculated)

Extinction coefficient

26,930 - 27,305 (calc based on 7 Y, 3 W, and 3 C residues)

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Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Type Residues Description Notes References

Domain

19 - 77

HTH cro/C1-type

UniProt:P03034


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<motif_map/>

Structure

See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

<beststructure> gene=Phage_lambda_cI taxon=10710 </beststructure>

Models

View models at:

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Structure figures

See Help:Jmol in EcoliWiki

full length lambda repressor bound to operator DNA
<jmol> <jmolApplet> <color>white</color> <uploadedFileContents >3BDN.pdb</uploadedFileContents> <script> wireframe off; spacefill off; trace off; reset;center {11.954998 19.6415 35.014}; rotate z 95.96; rotate y 86.35; rotate z 117.3; cartoon; select protein; color chain; </script> </jmolApplet> </jmol>
<jmol> <jmolCheckbox > <scriptWhenChecked > rotate on; </scriptWhenChecked > <scriptWhenUnchecked > rotate off; </scriptWhenUnchecked > <checked>false</checked> <text>rotate</text> </jmolCheckbox > <jmolButton><script>reset; reset;center {11.954998 19.6415 35.014}; rotate z 95.96; rotate y 86.35; rotate z 117.3; cartoon; select protein; color chain; </script><text>reset</text></jmolButton> </jmol>









Notes

Lambda repressor consists of an N-terminal DNA binding domain and a C-terminal oligomerization domain, connected by a flexible linker. The N-terminal domain in isolation dimerizes weakly through helix 5-helix 5 contacts. The C-terminal domain is required for dimerization and DNA binding at normal in vivo expression levels. Induction of phage lambda by the SOS response involves autoproteolysis at a specific site in the linker by the C-domain.

Gene Product Resources

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See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type Source Notes/Reference
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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

Genbank (EcoliWiki Page)

Genbank:NP_040628.1


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Notes

Links

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Name URL Comments
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References

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See Help:References for how to manage references in EcoliWiki.


Categories

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