mltA:Quickview: Difference between revisions

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!align=left |Standard Name
!align=left {{table_heading_style}} |Standard Name
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''mltA''  
''mltA''  
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!align=left |Gene Synonym(s)
!align=left {{table_heading_style}} |Gene Synonym(s)
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''ECK2809, b2813, JW2784, waaN, mlt, ygdM, G330''<ref name='LIB:Riley_2006'/><ref name='LIB:EcoCyc10.6'/>
''ECK2809, b2813, JW2784, waaN, mlt, ygdM, G330''<ref name='LIB:Riley_2006'/><ref name='LIB:EcoCyc10.6'/>
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!align=left |Product Desc.
!align=left {{table_heading_style}} |Product Desc.
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membrane-bound lytic murein transglycosylase A<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>
membrane-bound lytic murein transglycosylase A<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>
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Membrane-bound lytic transglycosylase A, murein hydrolase; periplasmic OM-attached lipoprotein<ref name='LIB:EcoGene'/>
Membrane-bound lytic transglycosylase A, murein hydrolase; periplasmic OM-attached lipoprotein<ref name='LIB:EcoGene'/>
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!align=left |Product Synonyms(s)
!align=left {{table_heading_style}} |Product Synonyms(s)
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membrane-bound lytic murein transglycosylase A<ref name='LIB:Riley_2006'/>, B2813<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, YgdM<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, Mlt<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, MltA<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>  
membrane-bound lytic murein transglycosylase A<ref name='LIB:Riley_2006'/>, B2813<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, YgdM<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, Mlt<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, MltA<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>  
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!align=left |Knock-Out Phenotype
!align=left {{table_heading_style}} |Function from GO
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'''Biological Process'''
* GO:0000910 cytokinesis ([http://www.geneontology.org/GO.evidence.shtml IGI])
* GO:0009252 peptidoglycan biosynthetic process ([http://www.geneontology.org/GO.evidence.shtml IDA])
'''Molecular Function'''
* GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds ([http://www.geneontology.org/GO.evidence.shtml IDA])
* GO:0005515 protein binding ([http://www.geneontology.org/GO.evidence.shtml IPI])
* GO:0008933 lytic transglycosylase activity ([http://www.geneontology.org/GO.evidence.shtml IDA])
'''Cellular Component'''
* GO:0005887 integral to plasma membrane ([http://www.geneontology.org/GO.evidence.shtml IDA])


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!align=left |Regulation/Expression
!align=left {{table_heading_style}} |Knock-Out Phenotype
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!align=left {{table_heading_style}} |Regulation/Expression
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transcription unit(s): [[:Category:Txn_unit:mltA|mltA]]<ref name='LIB:EcoCyc10.6'/>  
transcription unit(s): [[:Category:Txn_unit:mltA|mltA]]<ref name='LIB:EcoCyc10.6'/>  
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!align=left |Regulation/Activity
!align=left {{table_heading_style}} |Regulation/Activity
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!align=left {{table_heading_style}} |Quick Links
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[http://ecoliwiki.net/tools/display_dna.php?gene=mltA&loc=MG1655:2945200..2944103,W3110:2945834..2944737,DH10B:3039070..3037973,REL606:2841797..2840700 DNA display]&nbsp;&nbsp;&nbsp; [http://ecoliwiki.net/tools/display_protein.php?f=NC_000913&start=2841797&end=2840700&gene=mltA&aa=mkgrwvkyllmgtvvamlaacsskptdrgqqykdgkftqpfslvnqpdavgapinagdfaeqinhirnssprlygnqsnvynavqewlraggdtrnmrqfgidawqmegadnygnvqftgyytpviqarhtrqgefqypiyrmppkrgrlpsraeiyagalsdkyilaysnslmdnfimdvqgsgyidfgdgsplnffsyagknghayrsigkvlidrgevkkedmsmqairhwgethseaevrelleqnpsfvffkpqsfapvkgasavplvgrasvasdrsiippgttllaevplldnngkfngqyelrlmvaldvggaikgqhfdiyqgigpeaghragwynhygrvwvlktapgagnvfsg Protein display]&nbsp;&nbsp;&nbsp; [http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=Search&Term=mltA+AND+escherichia+coli Pubmed(mltA)]&nbsp;&nbsp;&nbsp; [http://trimer.tamu.edu/cgi-bin/textpresso/2.1/ecoli/search?searchstring=mltA Textpresso(mltA)]


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Revision as of 23:43, 21 January 2010

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions

See Help:Quickview for help with entering information in the Quickview table.

Standard Name

mltA

Gene Synonym(s)

ECK2809, b2813, JW2784, waaN, mlt, ygdM, G330[1][2]

Product Desc.

membrane-bound lytic murein transglycosylase A[2][3]

Membrane-bound lytic transglycosylase A, murein hydrolase; periplasmic OM-attached lipoprotein[4]

Product Synonyms(s)

membrane-bound lytic murein transglycosylase A[1], B2813[2][1], YgdM[2][1], Mlt[2][1], MltA[2][1]

Function from GO

Biological Process

Molecular Function

Cellular Component

Knock-Out Phenotype
Regulation/Expression

transcription unit(s): mltA[2]

Regulation/Activity
Quick Links

DNA display    Protein display    Pubmed(mltA)    Textpresso(mltA)

See Help:Quickview for help with entering information in the Quickview table.

Notes

[back to top]


MltA cleaves the glycosidic bonds between the N-acetylmuramic acid and N-acetylglucosamine residues in murein. Unlike Slt and MltB, MltA can use peptide-free glycan as substrate. First 20 aa are a type II signal peptide. MltA forms a complex with MrcB and MipA.[4]



References

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  1. ↑ 1.0 1.1 1.2 1.3 1.4 1.5 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 2.4 2.5 2.6 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.