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!align=left |Standard Name
!align=left {{table_heading_style}} |Standard Name
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''hns''  
''hns''  
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!align=left |Gene Synonym(s)
!align=left {{table_heading_style}} |Gene Synonym(s)
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''ECK1232, b1237, JW1225, bglY, cur, drc, drdX, drs, irk, mssyA, msyA, osmZ, pilG, topX, virR, hnsA, topS, B1, H1''<ref name='LIB:Riley_2006'/>
''ECK1232, b1237, JW1225, bglY, cur, drc, drdX, drs, irk, mssyA, msyA, osmZ, pilG, topX, virR, hnsA, topS, B1, H1''<ref name='LIB:Riley_2006'/>
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!align=left |Product Desc.
!align=left {{table_heading_style}} |Product Desc.
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H-NS transcriptional dual regulator<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>
H-NS transcriptional dual regulator<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>
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DNA-binding global regulator H-NS; diverse mutant phenotypes affecting transcription, transposition, inversion, cryptic-gene expression; involved in chromosome organization; preferentially binds bent DNA; has N-terminal dimerization domain<ref name='LIB:EcoGene'/>
DNA-binding global regulator H-NS; diverse mutant phenotypes affecting transcription, transposition, inversion, cryptic-gene expression; involved in chromosome organization; preferentially binds bent DNA; has N-terminal dimerization domain<ref name='LIB:EcoGene'/>
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!align=left |Product Synonyms(s)
!align=left {{table_heading_style}} |Product Synonyms(s)
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global DNA-binding transcriptional dual regulator H-NS<ref name='LIB:Riley_2006'/>, B1237<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, Irk<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, MsyA<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, PilG<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, TopS<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, TopX<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, VirR<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, Drs<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, Drc<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, Cur<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, Hns<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, DrdX<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, BglY<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, HnsA<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, DNA-binding protein HLP-II (HU, BH2, HD, NS); pleiotropic regulator<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, OsmZ<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, DNA-binding protein HLP-II (HU, BH2, HD, NS)<ref name='LIB:EcoCyc11.1'/><ref name='LIB:Riley_2006'/>  
global DNA-binding transcriptional dual regulator H-NS<ref name='LIB:Riley_2006'/>, B1237<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, Irk<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, MsyA<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, PilG<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, TopS<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, TopX<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, VirR<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, Drs<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, Drc<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, Cur<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, Hns<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, DrdX<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, BglY<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, HnsA<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, DNA-binding protein HLP-II (HU, BH2, HD, NS); pleiotropic regulator<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, OsmZ<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, DNA-binding protein HLP-II (HU, BH2, HD, NS)<ref name='LIB:EcoCyc11.1'/><ref name='LIB:Riley_2006'/>  
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!align=left |Knock-Out Phenotype
!align=left {{table_heading_style}} |Function from GO
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!align=left |Regulation/Expression
!align=left {{table_heading_style}} |Knock-Out Phenotype
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!align=left {{table_heading_style}} |Regulation/Expression
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transcription unit(s): [[:Category:Txn_unit:hns|hns]]<ref name='LIB:EcoCyc10.6'/>, OP00190  
transcription unit(s): [[:Category:Txn_unit:hns|hns]]<ref name='LIB:EcoCyc10.6'/>, OP00190  
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!align=left |Regulation/Activity
!align=left {{table_heading_style}} |Regulation/Activity
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!align=left {{table_heading_style}} |Quick Links
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[http://ecoliwiki.net/tools/display_dna.php?gene=hns&loc=MG1655:1292145..1291732,W3110:1294499..1294086,DH10B:1332386..1331973,REL606:1292716..1292303 DNA display]&nbsp;&nbsp;&nbsp; [http://ecoliwiki.net/tools/display_protein.php?f=NC_000913&start=1292716&end=1292303&gene=hns&aa=msealkilnnirtlraqarectletleemleklevvvnerreeesaaaaeveertrklqqyremliadgidpnellnslaavksgtkakraqrpakysyvdengetktwtgqgrtpavikkamdeqgkslddflikq Protein display]&nbsp;&nbsp;&nbsp; [http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=Search&Term=hns+AND+escherichia+coli Pubmed(hns)]&nbsp;&nbsp;&nbsp; [http://trimer.tamu.edu/cgi-bin/textpresso/2.1/ecoli/search?searchstring=hns Textpresso(hns)]


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Revision as of 23:52, 21 January 2010

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions

See Help:Quickview for help with entering information in the Quickview table.

Standard Name

hns

Gene Synonym(s)

ECK1232, b1237, JW1225, bglY, cur, drc, drdX, drs, irk, mssyA, msyA, osmZ, pilG, topX, virR, hnsA, topS, B1, H1[1]

Product Desc.

H-NS transcriptional dual regulator[2][3]

DNA-binding global regulator H-NS; diverse mutant phenotypes affecting transcription, transposition, inversion, cryptic-gene expression; involved in chromosome organization; preferentially binds bent DNA; has N-terminal dimerization domain[4]

Product Synonyms(s)

global DNA-binding transcriptional dual regulator H-NS[1], B1237[2][1], Irk[2][1], MsyA[2][1], PilG[2][1], TopS[2][1], TopX[2][1], VirR[2][1], Drs[2][1], Drc[2][1], Cur[2][1], Hns[2][1], DrdX[2][1], BglY[2][1], HnsA[2][1], DNA-binding protein HLP-II (HU, BH2, HD, NS); pleiotropic regulator[2][1], OsmZ[2][1], DNA-binding protein HLP-II (HU, BH2, HD, NS)[3][1]

Function from GO
Knock-Out Phenotype
Regulation/Expression

transcription unit(s): hns[2], OP00190

Regulation/Activity
Quick Links

DNA display    Protein display    Pubmed(hns)    Textpresso(hns)

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See Help:Quickview for help with entering information in the Quickview table.

Notes

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HN-S forms heteromeric complexes with Hha and Cnu, which modulates HN-S function, expression and stability. Mutations affect chromosomal supercoiling. HT_Cmplx32_Mem: CspC+Hns+HupA.[4]



References

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  1. ↑ 1.00 1.01 1.02 1.03 1.04 1.05 1.06 1.07 1.08 1.09 1.10 1.11 1.12 1.13 1.14 1.15 1.16 1.17 1.18 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.00 2.01 2.02 2.03 2.04 2.05 2.06 2.07 2.08 2.09 2.10 2.11 2.12 2.13 2.14 2.15 2.16 2.17 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
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