trmD:Gene Product(s): Difference between revisions

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GO:0009451
GO:0030488
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RNA modification
tRNA methylation
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PMID:342495
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IMP: Inferred from Mutant Phenotype
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P  
P
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Seeded from Riley et  al 2006 <ref name='LIB:Riley_2006'/>.
Seeded from EcoCyc
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required fields missing 
complete
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GO:0030488
GO:0009451
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tRNA methylation
RNA modification
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PMID:342495
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IMP: Inferred from Mutant Phenotype
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P
P  
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Seeded from EcoCyc
Seeded from Riley et  al 2006 <ref name='LIB:Riley_2006'/>.
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complete
required fields missing 


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!align=left {{table heading style}} |Mol. Wt
!align=left {{table heading style}} |Mol. Wt
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28.42 kDa (calc) <ref name='LIB:EcoCyc10.6'/>
28.422 kDa
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!align=left {{table heading style}} |pI
!align=left {{table heading style}} |pI
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5.7 (calculated)
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!align=left {{table heading style}} |Extinction coefficient
!align=left {{table heading style}} |Extinction coefficient
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36440 - 36690 (calc based on 6 Y, 5 W, and 2 C residues)  
36,440 - 36,690 (calc based on 6 Y, 5 W, and 2 C residues)


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Revision as of 22:07, 19 June 2009

{{#css:Suppresslinks.css}}<css>h1 .editsection { display:none;} h2 .editsection { display:none;}</css>

Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.

Standard name

TrmD

Synonyms

tRNA (guanine-1-)-methyltransferase[1], B2607[2][1], TrmD[2][1]

Product description

TrmD[2][3];

Component of tRNA (guanine-1-)-methyltransferase[3]

tRNA m(1)G37 methyltransferase[4]

EC number (for enzymes)
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Notes

Function

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Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference(s) Evidence Code with/from Aspect Notes Status
GO:0009019

tRNA (guanine-N1-)-methyltransferase activity

GO_REF:0000003
GO_REF:0000020

IEA: Inferred from Electronic Annotation

EC:2.1.1.31
HAMAP:MF_00605

F

Seeded from EcoCyc 12.5 [5]

complete

GO:0005737

cytoplasm

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0963

C

Seeded from EcoCyc 12.5 [5]

complete

GO:0003723

RNA binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR002649

F

Seeded from EcoCyc [6]

complete

GO:0006400

tRNA modification

GO_REF:0000020

IEA: Inferred from Electronic Annotation

HAMAP:MF_00605

P

Seeded from EcoCyc [6]

complete

GO:0008033

tRNA processing

GO_REF:0000002
GO_REF:0000004

IEA: Inferred from Electronic Annotation

InterPro:IPR002649
SP_KW:KW-0819

P

Seeded from EcoCyc [6]

complete

GO:0008168

methyltransferase activity

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0489

F

Seeded from EcoCyc [6]

complete

GO:0008175

tRNA methyltransferase activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR002649

F

Seeded from EcoCyc [6]

complete

GO:0016740

transferase activity

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0808

F

Seeded from EcoCyc [6]

complete

GO:0030488

tRNA methylation

PMID:342495[7]

IMP: Inferred from Mutant Phenotype

P

Seeded from EcoCyc [6]

complete

GO:0003723

RNA binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR002649

F

Seeded from EcoCyc

complete

GO:0005737

cytoplasm

GO_REF:0000020
GO_REF:0000004
GO_REF:0000023

IEA: Inferred from Electronic Annotation

HAMAP:MF_00605
SP_KW:KW-0963
SP_SL:SL-0086

C

Seeded from EcoCyc

complete

GO:0006400

tRNA modification

GO_REF:0000020

IEA: Inferred from Electronic Annotation

HAMAP:MF_00605

P

Seeded from EcoCyc

complete

GO:0008033

tRNA processing

GO_REF:0000002
GO_REF:0000004

IEA: Inferred from Electronic Annotation

InterPro:IPR002649
SP_KW:KW-0819

P

Seeded from EcoCyc

complete

GO:0008168

methyltransferase activity

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0489

F

Seeded from EcoCyc

complete

GO:0008175

tRNA methyltransferase activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR002649

F

Seeded from EcoCyc

complete

GO:0009019

tRNA (guanine-N1-)-methyltransferase activity

GO_REF:0000020
GO_REF:0000003
PMID:6337136[8]

IDA: Inferred from Direct Assay

HAMAP:MF_00605
EC:2.1.1.31

F

Seeded from EcoCyc

complete

GO:0016740

transferase activity

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0808

F

Seeded from EcoCyc

complete

GO:0030488

tRNA methylation

PMID:342495[7]

IMP: Inferred from Mutant Phenotype

P

Seeded from EcoCyc

complete

GO:0009451

RNA modification

P

Seeded from Riley et al 2006 [1].

required fields missing

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Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type Partner Notes References Evidence

Protein

Subunits of tRNA (guanine-1-)-methyltransferase

could be indirect


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Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

Compartment Description Evidence Notes
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Notes

Structure and Physical Properties

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Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Sequence

at EcoCyc 

MWIGIISLFP EMFRAITDYG VTGRAVKNGL LSIQSWSPRD FTHDRHRTVD DRPYGGGPGM
LMMVQPLRDA IHAAKAAAGE GAKVIYLSPQ GRKLDQAGVS ELATNQKLIL VCGRYEGIDE
RVIQTEIDEE WSIGDYVLSG GELPAMTLID SVSRFIPGVL GHEASATEDS FAEGLLDCPH
YTRPEVLEGM EVPPVLLSGN HAEIRRWRLK QSLGRTWLRR PELLENLALT EEQARLLAEF
KTEHAQQQHK HDGMA
Length

255

Mol. Wt

28.422 kDa

pI

5.7 (calculated)

Extinction coefficient

36,440 - 36,690 (calc based on 6 Y, 5 W, and 2 C residues)

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Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Type Residues Description Notes
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<motif_map/>

Structure See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

<beststructure>trmD 562</beststructure>

Models

View models at:

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Notes

Gene Product Resources

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See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type Source Notes/Reference
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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

EcoCyc (EcoliWiki Page)

EcoCyc:EG11023-MONOMER

UniProt (EcoliWiki Page)

UniProt:P0A873

PFAM (EcoliWiki Page)

PFAM:PF01746

RefSeq (EcoliWiki Page)

RefSeq:NP_417098

ModBase (EcoliWiki Page)

ModBase:P0A873


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Notes

Links

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Name URL Comments
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References

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  1. ↑ 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  5. ↑ 5.0 5.1 EcoCyc (release 12.5; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  6. ↑ 6.0 6.1 6.2 6.3 6.4 6.5 6.6 EcoCyc (release 13.0; 2009) Keseler, IM et al. (2009) Nucleic Acids Res. 37(Database issue):D464-70
  7. ↑ 7.0 7.1 Björk, GR & Kjellin-Stråby, K (1978) Escherichia coli mutants with defects in the biosynthesis of 5-methylaminomethyl-2-thio-uridine or 1-methylguanosine in their tRNA. J Bacteriol 133 508-17 PubMed
  8. ↑ Hjalmarsson, KJ et al. (1983) Purification and characterization of transfer RNA (guanine-1)methyltransferase from Escherichia coli. J. Biol. Chem. 258 1343-51 PubMed


Categories

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