Phage lambda cI:Gene Product(s)

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Gene

Gene Product(s)

Expression

Evolution

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Nomenclature

Function

Interactions

Localization

Sequence

Domains

Structure

Resources

Accessions

Links

References

Suggestions

Nomenclature

Standard name	cI
Synonyms	cI, lambdap88
Product description	repressor
EC number (for enzymes)
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Function

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Gene Ontology

Qualifier	GO ID	GO term name	Reference(s)	Evidence Code	with/from	Aspect	Notes	Status
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Interactions

Localization

Compartment	Description	Evidence	Notes
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Structure and Physical Properties

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Physical Properties

Sequence	MSTKKKPLTQ EQLEDARRLK AIYEKKKNEL GLSQESVADK MGMGQSGVGA LFNGINALNA YNAALLAKIL KVSVEEFSPS IAREIYEMYE AVSMQPSLRS EYEYPVFSHV QAGMFSPELR TFTKGDAERW VSTTKKASDS AFWLEVEGNS MTAPTGSKPS FPDGMLILVD PEQAVEPGDF CIARLGGDEF TFKKLIRDSG QVFLQPLNPQ YPMIPCNESC SVVGKVIASQ WPEETFG
Mol. Wt	26.21 kDa (calc)
pI
Extinction coefficient
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Domains/Motifs/Modification Sites

Type Residues Description Notes edit table

<motif_map/>

Structure

See Help:Jmol in EcoliWiki full length lambda repressor bound to operator DNA <jmol> <jmolApplet> <color>white</color> <uploadedFileContents >3BDN.pdb</uploadedFileContents> <script> wireframe off; spacefill off; trace off; reset;center {11.954998 19.6415 35.014}; rotate z 95.96; rotate y 86.35; rotate z 117.3; cartoon; select protein; color chain; </script> </jmolApplet> </jmol> <jmol> <jmolCheckbox > <scriptWhenChecked > rotate on; </scriptWhenChecked > <scriptWhenUnchecked > rotate off; </scriptWhenUnchecked > <checked>false</checked> <text>rotate</text> </jmolCheckbox > <jmolButton><script>reset; reset;center {11.954998 19.6415 35.014}; rotate z 95.96; rotate y 86.35; rotate z 117.3; cartoon; select protein; color chain; </script><text>reset</text></jmolButton> </jmol>

Coming soon... A new Structure table. We are currently working on reformatting the table to provide more information and references to structures and computational models. We would love to add your research here! If you are interested in adding your data, contact Daniel. You can find our [Blast results here].

See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures	X-ray	X-ray
Models	lambda
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Notes

Lambda repressor consists of an N-terminal DNA binding domain and a C-terminal oligomerization domain, connected by a flexible linker. The N-terminal domain in isolation dimerizes weakly through helix 5-helix 5 contacts. The C-terminal domain is required for dimerization and DNA binding at normal in vivo expression levels. Induction of phage lambda by the SOS response involves autoproteolysis at a specific site in the linker by the C-domain.

Gene Product Resources

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Resource type	Source	Notes/Reference
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Accessions in Other Databases

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Database	Accession	Notes
Genbank (EcoliWiki Page)	Genbank:NP_040628.1
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Links

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Name	URL	Comments
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References

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Categories

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