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!align=left {{table_heading_style}} |Standard Name
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!align=left {{table_heading_style}} |Gene Synonym(s)
!align=left {{table_heading_style}} |Gene Synonym(s)
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!align=left {{table_heading_style}} |Quick Links
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[http://ecoliwiki.net/tools/display_dna.php?gene=hfq&loc=MG1655:4398311..4398619,W3110:4404968..4405276,DH10B:4498673..4498981,REL606:4378443..4378751 DNA display]    [http://ecoliwiki.net/tools/display_protein.php?f=NC_000913&start=4378443&end=4378751&gene=hfq&aa=makgqslqdpflnalrrervpvsiylvngiklqgqiesfdqfvillkntvsqmvykhaistvvpsrpvshhsnnagggtssnyhhgssaqntsaqqdseete Protein display]    [http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=Search&Term=hfq+AND+escherichia+coli Pubmed(hfq)]    [http://trimer.tamu.edu/cgi-bin/textpresso/2.1/ecoli/search?searchstring=hfq Textpresso(hfq)]
[http://ecoliwiki.net/tools/display_dna.php?gene=hfq&loc=MG1655:4398311..4398619,W3110:4404968..4405276,DH10B:4498673..4498981,REL606:4378443..4378751 DNA display]    [http://ecoliwiki.net/tools/display_protein.php?f=NC_000913&start=4378443&end=4378751&gene=hfq&aa=makgqslqdpflnalrrervpvsiylvngiklqgqiesfdqfvillkntvsqmvykhaistvvpsrpvshhsnnagggtssnyhhgssaqntsaqqdseete Protein display]    [http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=Search&Term=hfq+AND+escherichia+coli Pubmed(hfq)]    [http://trimer.tamu.edu/cgi-bin/textpresso/dev/search?q=hfq Textpresso(hfq)]


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Revision as of 22:15, 2 March 2010

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions

See Help:Quickview for help with entering information in the Quickview table.

Standard Name

hfq

Gene Synonym(s)

ECK4168, b4172, JW4130, HF-I, HF-1[1][2]

Product Desc.

RNA-binding protein that affects many cellular processes; homolog of mammalian Sm/Sm-like proteins[2][3];

Component of HF-I, host factor for RNA phage Q β replication[3]

Global regulator of sRNA function; host factor for RNA phage Q beta replication; HF-I; DNA- and RNA-binding protein; RNA chaperone; multiple regulatory roles: destabilzes ompA mRNA, improves rpoS translation, sRNA DsrA co-factor; binds RNAP; ATPase[4]

Product Synonyms(s)

HF-I, host factor for RNA phage Q beta replication product[1], B4172 product[2][1], Hfq product[2][1], HF-I product[2][1], host factor I product[2][1]

Function from GO

<GO_nr />

Knock-Out Phenotype
Regulation/Expression

transcription unit(s): yjeFE-amiB-mutL-miaA-hfq-hflXKC[2], ORF55-ORF17-amiB-mutL-miaA-hfq-hflXKC

Regulation/Activity
Quick Links

DNA display    Protein display    Pubmed(hfq)    Textpresso(hfq)

See Help:Quickview for help with entering information in the Quickview table.

Notes

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The C-terminal of Hfq is not necessary for hexamerization. RNA binding is located primarily at the N-terminal. Hfq has intrinsic ATPase activity (Sukhodolets, 2003; Arluison, 2007).[4]



References

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  1. ↑ 1.0 1.1 1.2 1.3 1.4 1.5 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 2.4 2.5 2.6 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.