emrE:Quickview: Difference between revisions

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!align=left {{table_heading_style}} |Function from GO
!align=left {{table_heading_style}} |Function from GO
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'''Biological Process'''
<GO_nr />
* GO:0042493 response to drug ([http://www.geneontology.org/GO.evidence.shtml IMP])
* GO:0006805 xenobiotic metabolic process ([http://www.geneontology.org/GO.evidence.shtml IMP])
* GO:0006810 transport ([http://www.geneontology.org/GO.evidence.shtml IDA])
'''Cellular Component'''
* GO:0016020 membrane ([http://www.geneontology.org/GO.evidence.shtml IDA])
* GO:0016021 integral to membrane ([http://www.geneontology.org/GO.evidence.shtml IDA])
'''Molecular Function'''
* GO:0015297 antiporter activity ([http://www.geneontology.org/GO.evidence.shtml IDA])
 
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!align=left {{table_heading_style}} |Knock-Out Phenotype
!align=left {{table_heading_style}} |Knock-Out Phenotype

Revision as of 19:43, 2 February 2010

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions

See Help:Quickview for help with entering information in the Quickview table.

Standard Name

emrE

Gene Synonym(s)

ECK0534, b0543, JW0531, mvrC, eb, mvrB, G6299[1][2]

Product Desc.

EmrE SMR transporter[2][3]

Multidrug resistance pump, DLP12 prophage; methylviologen sensitivity[4]

Product Synonyms(s)

DLP12 prophage; multidrug resistance protein[1], B0543[2][1], MvrC[2][1], EmrE[2][1]

Function from GO

<GO_nr />

Knock-Out Phenotype
Regulation/Expression

transcription unit(s): renD[2]

Regulation/Activity
Quick Links

DNA display    Protein display    Pubmed(emrE)    Textpresso(emrE)

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See Help:Quickview for help with entering information in the Quickview table.

Notes

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EmrE defunct PDB structures 1S7B and 2F2M, and any conclusions derived from these structures, have been retracted due to a software data inversion error (Ma, 2007; Chang, 2007). Correct structures are now available. EmrE belongs to the SMR efflux pump family, DMT superfamily. EmrE accomplishes multidrug efflux by coupling conformational changes between two heterodimers with proton gradient. Dual-topology membrane protein.[4]



References

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  1. ↑ 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 2.4 2.5 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
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