sbcC:Quickview: Difference between revisions
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!align=left | !align=left {{table_heading_style}} |Standard Name | ||
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''sbcC'' | ''sbcC'' | ||
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!align=left | !align=left {{table_heading_style}} |Gene Synonym(s) | ||
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''ECK0391, b0397, JW0387, rmuA''<ref name='LIB:Riley_2006'/> | ''ECK0391, b0397, JW0387, rmuA''<ref name='LIB:Riley_2006'/> | ||
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!align=left | !align=left {{table_heading_style}} |Product Desc. | ||
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ATP-dependent dsDNA exonuclease<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>; | ATP-dependent dsDNA exonuclease<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>; | ||
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DNA hairpin dsDNA 3'-exonuclease SbcCD, Mn(2+), ATP-dependent; ATP-independent 5' ssDNA endonuclease; required for recombinational repair of dsDNA breaks; cosuppressor with sbcB of recB recC mutations; heterodimeric<ref name='LIB:EcoGene'/> | DNA hairpin dsDNA 3'-exonuclease SbcCD, Mn(2+), ATP-dependent; ATP-independent 5' ssDNA endonuclease; required for recombinational repair of dsDNA breaks; cosuppressor with sbcB of recB recC mutations; heterodimeric<ref name='LIB:EcoGene'/> | ||
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!align=left | !align=left {{table_heading_style}} |Product Synonyms(s) | ||
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exonuclease, dsDNA, ATP-dependent<ref name='LIB:Riley_2006'/>, B0397<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, SbcC<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/> | exonuclease, dsDNA, ATP-dependent<ref name='LIB:Riley_2006'/>, B0397<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, SbcC<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/> | ||
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!align=left | !align=left {{table_heading_style}} |Function from GO | ||
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'''Molecular Function''' | |||
* GO:0005515 protein binding ([http://www.geneontology.org/GO.evidence.shtml IPI]) | |||
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!align=left | !align=left {{table_heading_style}} |Knock-Out Phenotype | ||
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!align=left {{table_heading_style}} |Regulation/Expression | |||
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transcription unit(s): [[:Category:Txn_unit:sbcC|sbcC]]<ref name='LIB:EcoCyc10.6'/> | transcription unit(s): [[:Category:Txn_unit:sbcC|sbcC]]<ref name='LIB:EcoCyc10.6'/> | ||
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!align=left | !align=left {{table_heading_style}} |Regulation/Activity | ||
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!align=left {{table_heading_style}} |Quick Links | |||
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[http://ecoliwiki.net/tools/display_dna.php?gene=sbcC&loc=MG1655:414977..411831,W3110:414977..411831,DH10B:354308..351162,REL606:384176..381030 DNA display] [http://ecoliwiki.net/tools/display_protein.php?f=NC_000913&start=384176&end=381030&gene=sbcC&aa=mkilslrlknlnslkgewkidftrepfasnglfaitgptgagkttlldaiclalyhetprlsnvsqsqndlmtrdtaeclaevefevkgeayrafwsqnrarnqpdgnlqvprvelarcadgkiladkvkdkleltatltgldygrftrsmllsqgqfaaflnakpkeraelleeltgteiygqisamvfeqhksarteleklqaqasgvtlltpeqvqsltaslqvltdeekqlitaqqqeqqslnwltrqdelqqeasrrqqalqqalaeeekaqpqlaalslaqparnlrphweriaehsaalahirqqieevntrlqstmalrasirhhaakqsaelqqqqqslntwlqehdrfrqwnnepagwraqfsqqtsdrehlrqwqqqlthaeqklnalaaitltltadevatalaqhaeqrplrqhlvalhgqivpqqkrlaqlqvaiqnvtqeqtqrnaalnemrqrykektqqladvkticeqeariktleaqraqlqagqpcplcgstshpaveayqalepgvnqsrllalenevkklgeegatlrgqldaitkqlqrdeneaqslrqdeqaltqqwqavtaslnitlqplddiqpwldaqdeherqlrllsqrhelqgqiaahnqqiiqyqqqieqrqqlllttltgyaltlpqedeeeswlatrqqeaqswqqrqneltalqnriqqltpiletlpqsdelphceetvvlenwrqvheqclalhsqqqtlqqqdvlaaqslqkaqaqfdtalqasvfddqqaflaalmdeqtltqleqlkqnlenqrrqaqtlvtqtaetlaqhqqhrpddglaltvtveqiqqelaqthqklrenttsqgeirqqlkqdadnrqqqqtlmqqiaqmtqqvedwgylnsligskegdkfrkfaqgltldnlvhlanqqltrlhgryllqrkasealevevvdtwqadavrdtrtlsggesflvslalalalsdlvshktridslfldegfgtldsetldtaldaldalnasgktigvishveamkeripvqikvkkinglgysklestfavk Protein display] [http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=Search&Term=sbcC+AND+escherichia+coli Pubmed(sbcC)] [http://trimer.tamu.edu/cgi-bin/textpresso/2.1/ecoli/search?searchstring=sbcC Textpresso(sbcC)] | |||
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Revision as of 23:33, 21 January 2010
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| Quickview | Gene | Gene Product(s) | Expression | Evolution | On One Page |
| References | Suggestions |
See Help:Quickview for help with entering information in the Quickview table.
| Standard Name |
sbcC |
|---|---|
| Gene Synonym(s) |
ECK0391, b0397, JW0387, rmuA[1] |
| Product Desc. |
ATP-dependent dsDNA exonuclease[2][3]; Component of SbcCD ATP-dependent dsDNA exonuclease[3] DNA hairpin dsDNA 3'-exonuclease SbcCD, Mn(2+), ATP-dependent; ATP-independent 5' ssDNA endonuclease; required for recombinational repair of dsDNA breaks; cosuppressor with sbcB of recB recC mutations; heterodimeric[4] |
| Product Synonyms(s) |
exonuclease, dsDNA, ATP-dependent[1], B0397[2][1], SbcC[2][1] |
| Function from GO |
Molecular Function
|
| Knock-Out Phenotype | |
| Regulation/Expression | |
| Regulation/Activity | |
| Quick Links | |
| edit table |
See Help:Quickview for help with entering information in the Quickview table.
Notes
SbcCD can cleave dsDNA 5' ends sealed by a hairpin or by covalent linko a protein. SbcCD limits recombination between short inverted repeats, but is also reported to be required for palindrome-stimulated deletion. SbcCD protein forms a large 1.2 megadalton complex. Second amino acid was sequenced in protein as Gly, but in all DNA samples is a Lys codon. Coiled coil protein.[4]
References
- ↑ 1.0 1.1 1.2 1.3 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
- ↑ 2.0 2.1 2.2 2.3 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.