mdh:Quickview: Difference between revisions

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Quickview

Standard Name	mdh
Gene Synonym(s)	ECK3225, b3236, JW3205^[1], JW3205
Product Desc.	Mdh^[2]^[3]; Component of malate dehydrogenase^[2]^[3] Malate dehydrogenase, NAD-dependent^[4]
Product Synonyms(s)	malate dehydrogenase, NAD(P)-binding^[1], B3236^[2]^[1], Mdh^[2]^[1] , ECK3225, JW3205, b3236
Function from GO	<GO_nr />
Knock-Out Phenotype
Regulation/Expression	transcription unit(s): mdh^[2], OP00149
Regulation/Activity
Quick Links
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Notes

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Mdh is elevated 4X during growth at 4C (enabled by Oleispira antarctica Cpn10/60 transgene). Deletion of mdh induces growth defects on all substrates except glucose. After four hours of Zn(II) stress, protein levels increased (Easton, 2006).^[4]

References

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↑ ^1.0 ^1.1 ^1.2 ^1.3 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
↑ ^2.0 ^2.1 ^2.2 ^2.3 ^2.4 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
↑ ^3.0 ^3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
↑ ^4.0 ^4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.

[LIB:Riley_2006-1] 1.0 ^1.1 ^1.2 ^1.3 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)

[LIB:EcoCyc10.6-2] 2.0 ^2.1 ^2.2 ^2.3 ^2.4 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7

[LIB:EcoCyc11.1-3] 3.0 ^3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7

[LIB:EcoGene-4] 4.0 ^4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.

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 <noinclude>{{TabsTop}}
 {{Tab On|Quickview|mdh}}{{Tab|Gene|mdh}}{{Tab|Gene Product(s)|mdh}}{{Tab|Expression|mdh}}{{Tab|Evolution|mdh}}{{Tab|On One Page|mdh}}{{TabsBottom}}
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 |-
-!{{table_heading_style}} |Gene Name
+!align=left {{table_heading_style}} |Standard Name
-|
+||
-[[mdh:Gene|''mdh]]'' (synonyms: ''ECK3225, b3236, JW3205'')<ref name='LIB:Riley_2006'/>
+''mdh''
 |-
-!{{table_heading_style}} |Product(s)
+!align=left {{table_heading_style}} |Gene Synonym(s)
-|
+||
-[[mdh:Gene_Product(s)|Mdh product]]<ref name='LIB:Riley_2006'/>: malate dehydrogenase, NAD(P)-binding product, B3236 product
+''ECK3225, b3236, JW3205''<ref name='LIB:Riley_2006'/>, JW3205''
 |-
-!{{table_heading_style}} |Description
+!align=left {{table_heading_style}} |Product Desc.
-|
+||
-Mdh<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>
+Mdh<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>;
-Component of [[:Category:Complex:malate dehydrogenase|malate dehydrogenase]]<ref name='LIB:EcoCyc10.6'/>
+Component of [[:Category:Complex:malate dehydrogenase|malate dehydrogenase]]<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>
+Malate dehydrogenase, NAD-dependent<ref name='LIB:EcoGene'/>
+|-
+!align=left {{table_heading_style}} |Product Synonyms(s)
+||
+''malate dehydrogenase, NAD(P)-binding<ref name='LIB:Riley_2006'/>, B3236<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, Mdh<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/> , ECK3225, JW3205, b3236''
+|-
+!align=left {{table_heading_style}} |Function from GO
+||
+<GO_nr />
 |-
-!{{table_heading_style}} |Knock-Out Phenotype
+!align=left {{table_heading_style}} |Knock-Out Phenotype
-|
+||
 |-
-!{{table_heading_style}} |Regulation/Expression
+!align=left {{table_heading_style}} |Regulation/Expression
-|
+||
 transcription unit(s): [[:Category:Txn_unit:mdh|mdh]]<ref name='LIB:EcoCyc10.6'/>, OP00149
 |-
-!{{table_heading_style}} |Regulation/Activity
+!align=left {{table_heading_style}} |Regulation/Activity
-|
+||
 |-
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+!align=left {{table_heading_style}} |Quick Links
+||
+[[File:porteco.png|link=http://porteco.org/AjaxSearch.jsp?searchString=mdh&s=search]] [[File:EcoCyc.gif|link=http://biocyc.org/ECOLI/NEW-IMAGE?type=NIL&object=EG10576]] [[File:regulondb.jpg|link=http://regulondb.ccg.unam.mx/gene?term=ECK120000569&organism=ECK12&format=jsp&type=gene ]] <br/><br/> [[File:dnadisplay.png|link=http://ecoliwiki.net/tools/display_dna.php?gene=mdh&loc=MG1655%3A3382290..3381352,W3110%3A3384123..3383185,REL606%3A3312165..3311227,DH10B%3A3480035..3479097,BW2952%3A3268500..3269438]] [[File:proteindisplay.png|link=http://ecoliwiki.net/tools/display_protein.php?f=NC_000913&start=3268500&end=3269438&gene=mdh&aa=mkvavlgaaggigqalalllktqlpsgselslydiapvtpgvavdlshiptavkikgfsgedatpalegadvvlisagvarkpgmdrsdlfnvnagivknlvqqvaktcpkacigiitnpvnttvaiaaevlkkagvydknklfgvttldiirsntfvaelkgkqpgevevpvigghsgvtilpllsqvpgvsfteqevadltkriqnagtevveakagggsatlsmgqaaarfglslvralqgeqgvvecayvegdgqyarffsqplllgkngveerksigtlsafeqnalegmldtlkkdialgeefvnk]]&nbsp;&nbsp;  [[File:pubmed.jpg|link=http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=Search&Term=mdh+AND+escherichia+coli]]&nbsp;&nbsp;  [[File:textpresso.jpg|link=http://textpresso.tamu.edu/cgi-bin/textpresso/search?q=mdh]]&nbsp;&nbsp;
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 <protect><!--Quickview_notes--></protect>
-==Notes==
+===Notes===
+{{BacktoTop}}
+Mdh is elevated 4X during growth at 4C (enabled by Oleispira antarctica Cpn10/60 transgene).  Deletion of mdh induces growth defects on all substrates except glucose. After four hours of Zn(II) stress, protein levels increased (Easton, 2006).<ref name='LIB:EcoGene'/>
 <noinclude>
 ==References==
+{{BacktoTop}}
 <references/>
 </noinclude>

mdh:Quickview: Difference between revisions

Latest revision as of 21:48, 27 May 2013

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