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{| | {| id="D49b0228a6fa90" class=" tableEdit New_Quickview_Table" | ||
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!align=left {{table_heading_style}} |Standard Name | !align=left {{table_heading_style}} |Standard Name | ||
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''rho'' | |||
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!align=left {{table_heading_style}} |Gene Synonym(s) | !align=left {{table_heading_style}} |Gene Synonym(s) | ||
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''ECK3775, b3783, JW3756, nitA, nusD, psuA, rnsC, sun, tsu, psu, sbaA, suA''<ref name='LIB:Riley_2006'/>, hdf, tabC'' | |||
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!align=left {{table_heading_style}} |Product Desc. | !align=left {{table_heading_style}} |Product Desc. | ||
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transcription termination factor Rho; polarity suppressor<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>; | |||
Component of [[:Category:Complex:transcription termination factor Rho|transcription termination factor Rho]]<ref name='LIB:EcoCyc11.1'/> | |||
Transcription termination factor Rho; bicyclomycin target<ref name='LIB:EcoGene'/> | |||
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!align=left {{table_heading_style}} |Product Synonyms(s) | !align=left {{table_heading_style}} |Product Synonyms(s) | ||
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''transcription termination factor<ref name='LIB:Riley_2006'/>, B3783<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, RnsC<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, Tsu<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, Sun<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, NusD<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, Psu<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, SbaA<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, PsuA<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, NitA<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, Rho<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/> , ECK3775, hdf, JW3756, nitA, nusD, psuA, rnsC, sbaA, sun, tabC, tsu, b3783'' | |||
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!align=left {{table_heading_style}} |Function from GO | |||
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<GO_nr /> | |||
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!align=left {{table_heading_style}} |Knock-Out Phenotype | !align=left {{table_heading_style}} |Knock-Out Phenotype | ||
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!align=left {{table_heading_style}} |Regulation/Expression | !align=left {{table_heading_style}} |Regulation/Expression | ||
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transcription unit(s): [[:Category:Txn_unit:rhoL|rhoL]]<ref name='LIB:EcoCyc10.6'/>, [[:Category:Txn_unit:rhoL-rho|rhoL-rho]]<ref name='LIB:EcoCyc10.6'/>, rho | |||
|- | |- | ||
!align=left {{table_heading_style}} |Regulation/Activity | !align=left {{table_heading_style}} |Regulation/Activity | ||
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[[File:porteco.png|link=http://porteco.org/AjaxSearch.jsp?searchString=rho&s=search]] [[File:EcoCyc.gif|link=http://biocyc.org/ECOLI/NEW-IMAGE?type=NIL&object=EG10845]] [[File:regulondb.jpg|link=http://regulondb.ccg.unam.mx/gene?term=ECK120000836&organism=ECK12&format=jsp&type=gene ]] <br/><br/> [[File:dnadisplay.png|link=http://ecoliwiki.net/tools/display_dna.php?gene=rho&loc=MG1655%3A3964440..3965699,W3110%3A3670264..3669005,REL606%3A3928217..3929476,DH10B%3A4063360..4064619,BW2952%3A3854109..3855368]] [[File:proteindisplay.png|link=http://ecoliwiki.net/tools/display_protein.php?f=NC_000913&start=3854109&end=3855368&gene=rho&aa=mnltelkntpvselitlgenmglenlarmrkqdiifailkqhaksgedifgdgvleilqdgfgflrsadssylagpddiyvspsqirrfnlrtgdtisgkirppkegeryfallkvnevnfdkpenarnkilfenltplhansrlrmergngstedltarvldlaspigrgqrglivappkagktmllqniaqsiaynhpdcvlmvlliderpeevtemqrlvkgevvastfdepasrhvqvaemviekakrlvehkkdviilldsitrlarayntvvpasgkvltggvdanalhrpkrffgaarnveeggsltiiatalidtgskmdeviyeefkgtgnmelhlsrkiaekrvfpaidynrsgtrkeellttqeelqkmwilrkiihpmgeidameflinklamtktnddffemmkrs]] [[File:pubmed.jpg|link=http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=Search&Term=rho+AND+escherichia+coli]] [[File:textpresso.jpg|link=http://textpresso.tamu.edu/cgi-bin/textpresso/search?q=rho]] | |||
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===Notes=== | ===Notes=== | ||
{{BacktoTop}} | {{BacktoTop}} | ||
The ''rho'' gene is often misannotated as a polarity suppressor. Mutations in ''rho'' suppress polarity.<ref name='PMID:132662'/><ref name='PMID:135845'/><ref name='PMID:790156'/><ref name='PMID:6461649'/><ref name='PMID:154103'/> Wild type ''rho'' is the source of polarity. | * The ''rho'' gene is often misannotated as a polarity suppressor. Mutations in ''rho'' suppress polarity.<ref name='PMID:132662'/><ref name='PMID:135845'/><ref name='PMID:790156'/><ref name='PMID:6461649'/><ref name='PMID:154103'/> Wild type ''rho'' is the source of polarity. | ||
* ''rho'' has been shown to be an essential gene (Das, 1976; Bubunenko, 2007).<ref name='LIB:EcoGene'/> | |||
rho has been shown to be an essential gene (Das, 1976; Bubunenko, 2007).<ref name='LIB:EcoGene'/> | * ''rho'' is required to maintain genomic integrity by resolving transcription/replication conflicts <ref name='PMID:21183718'/> | ||
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==References== | ==References== | ||
Latest revision as of 21:55, 27 May 2013
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| Quickview | Gene | Gene Product(s) | Expression | Evolution | On One Page |
| References | Suggestions |
| Standard Name |
rho |
|---|---|
| Gene Synonym(s) |
ECK3775, b3783, JW3756, nitA, nusD, psuA, rnsC, sun, tsu, psu, sbaA, suA[1], hdf, tabC |
| Product Desc. |
transcription termination factor Rho; polarity suppressor[2][3]; Component of transcription termination factor Rho[3] Transcription termination factor Rho; bicyclomycin target[4] |
| Product Synonyms(s) |
transcription termination factor[1], B3783[2][1], RnsC[2][1], Tsu[2][1], Sun[2][1], NusD[2][1], Psu[2][1], SbaA[2][1], PsuA[2][1], NitA[2][1], Rho[2][1] , ECK3775, hdf, JW3756, nitA, nusD, psuA, rnsC, sbaA, sun, tabC, tsu, b3783 |
| Function from GO |
<GO_nr /> |
| Knock-Out Phenotype | |
| Regulation/Expression | |
| Regulation/Activity | |
| Quick Links | |
| edit table |
See Help:Quickview for help with entering information in the Quickview table.
Notes
- The rho gene is often misannotated as a polarity suppressor. Mutations in rho suppress polarity.[5][6][7][8][9] Wild type rho is the source of polarity.
- rho has been shown to be an essential gene (Das, 1976; Bubunenko, 2007).[4]
- rho is required to maintain genomic integrity by resolving transcription/replication conflicts [10]
References
- ↑ 1.00 1.01 1.02 1.03 1.04 1.05 1.06 1.07 1.08 1.09 1.10 1.11 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
- ↑ 2.00 2.01 2.02 2.03 2.04 2.05 2.06 2.07 2.08 2.09 2.10 2.11 2.12 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
- ↑ Das, A et al. (1976) Isolation and characterization of conditional lethal mutants of Escherichia coli defective in transcription termination factor rho. Proc. Natl. Acad. Sci. U.S.A. 73 1959-63 PubMed
- ↑ Korn, LJ & Yanofsky, C (1976) Polarity suppressors defective in transcription termination at the attenuator of the tryptophan operon of Escherichia coli have altered rho factor. J. Mol. Biol. 106 231-41 PubMed
- ↑ Belfort, M & Oppenheim, AB (1976) Efficient suppression of the requirement for N function of bacteriophage lambda by a Rho-defective E.coli suA mutant. Mol. Gen. Genet. 148 171-3 PubMed
- ↑ Richardson, JP & Carey, JL 3rd (1982) rho Factors from polarity suppressor mutants with defects in their RNA interactions. J. Biol. Chem. 257 5767-71 PubMed
- ↑ Das, A et al. (1978) Interaction of RNA polymerase and rho in transcription termination: coupled ATPase. Proc. Natl. Acad. Sci. U.S.A. 75 4828-32 PubMed
- ↑ Washburn, RS & Gottesman, ME (2011) Transcription termination maintains chromosome integrity. Proc. Natl. Acad. Sci. U.S.A. 108 792-7 PubMed


