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*  ** PLEASE DON'T EDIT THIS TABLE DIRECTLY.  Use the edit table link under the table. **  
*  ** PLEASE DON'T EDIT THIS TABLE DIRECTLY.  Use the edit table link under the table. **  
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|-
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!align=left {{table_heading_style}} |Standard Name
!align=left {{table_heading_style}} |Standard Name
||
''rho''
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!align=left {{table_heading_style}} |Gene Synonym(s)
!align=left {{table_heading_style}} |Gene Synonym(s)
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''ECK3775, b3783, JW3756, nitA, nusD, psuA, rnsC, sun, tsu, psu, sbaA, suA''<ref name='LIB:Riley_2006'/>, hdf, tabC''
|-
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!align=left {{table_heading_style}} |Product Desc.
!align=left {{table_heading_style}} |Product Desc.
||
transcription termination factor Rho;  polarity suppressor<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>;
Component of [[:Category:Complex:transcription termination factor Rho|transcription termination factor Rho]]<ref name='LIB:EcoCyc11.1'/>
Transcription termination factor Rho; bicyclomycin target<ref name='LIB:EcoGene'/>
|-
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!align=left {{table_heading_style}} |Product Synonyms(s)
!align=left {{table_heading_style}} |Product Synonyms(s)
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''transcription termination factor<ref name='LIB:Riley_2006'/>, B3783<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, RnsC<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, Tsu<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, Sun<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, NusD<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, Psu<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, SbaA<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, PsuA<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, NitA<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, Rho<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/> , ECK3775, hdf, JW3756, nitA, nusD, psuA, rnsC, sbaA, sun, tabC, tsu, b3783''
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!align=left {{table_heading_style}} |Function from GO
||
<GO_nr />
|-
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!align=left {{table_heading_style}} |Knock-Out Phenotype
!align=left {{table_heading_style}} |Knock-Out Phenotype
||
|-
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!align=left {{table_heading_style}} |Regulation/Expression
!align=left {{table_heading_style}} |Regulation/Expression
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transcription unit(s): [[:Category:Txn_unit:rhoL|rhoL]]<ref name='LIB:EcoCyc10.6'/>, [[:Category:Txn_unit:rhoL-rho|rhoL-rho]]<ref name='LIB:EcoCyc10.6'/>, rho
|-
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!align=left {{table_heading_style}} |Regulation/Activity
!align=left {{table_heading_style}} |Regulation/Activity
||


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!align=left {{table_heading_style}} |Quick Links
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[[File:porteco.png|link=http://porteco.org/AjaxSearch.jsp?searchString=rho&s=search]] [[File:EcoCyc.gif|link=http://biocyc.org/ECOLI/NEW-IMAGE?type=NIL&object=EG10845]] [[File:regulondb.jpg|link=http://regulondb.ccg.unam.mx/gene?term=ECK120000836&organism=ECK12&format=jsp&type=gene ]] <br/><br/> [[File:dnadisplay.png|link=http://ecoliwiki.net/tools/display_dna.php?gene=rho&loc=MG1655%3A3964440..3965699,W3110%3A3670264..3669005,REL606%3A3928217..3929476,DH10B%3A4063360..4064619,BW2952%3A3854109..3855368]] [[File:proteindisplay.png|link=http://ecoliwiki.net/tools/display_protein.php?f=NC_000913&start=3854109&end=3855368&gene=rho&aa=mnltelkntpvselitlgenmglenlarmrkqdiifailkqhaksgedifgdgvleilqdgfgflrsadssylagpddiyvspsqirrfnlrtgdtisgkirppkegeryfallkvnevnfdkpenarnkilfenltplhansrlrmergngstedltarvldlaspigrgqrglivappkagktmllqniaqsiaynhpdcvlmvlliderpeevtemqrlvkgevvastfdepasrhvqvaemviekakrlvehkkdviilldsitrlarayntvvpasgkvltggvdanalhrpkrffgaarnveeggsltiiatalidtgskmdeviyeefkgtgnmelhlsrkiaekrvfpaidynrsgtrkeellttqeelqkmwilrkiihpmgeidameflinklamtktnddffemmkrs]]&nbsp;&nbsp;  [[File:pubmed.jpg|link=http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=Search&Term=rho+AND+escherichia+coli]]&nbsp;&nbsp;  [[File:textpresso.jpg|link=http://textpresso.tamu.edu/cgi-bin/textpresso/search?q=rho]]&nbsp;&nbsp;
 
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===Notes===
===Notes===
{{BacktoTop}}
{{BacktoTop}}
The ''rho'' gene is often misannotated as a polarity suppressor.  Mutations in ''rho'' suppress polarity.<ref name='PMID:132662'/><ref name='PMID:135845'/><ref name='PMID:790156'/><ref name='PMID:6461649'/><ref name='PMID:154103'/>  Wild type ''rho'' is the source of polarity.
* The ''rho'' gene is often misannotated as a polarity suppressor.  Mutations in ''rho'' suppress polarity.<ref name='PMID:132662'/><ref name='PMID:135845'/><ref name='PMID:790156'/><ref name='PMID:6461649'/><ref name='PMID:154103'/>  Wild type ''rho'' is the source of polarity.
 
* ''rho'' has been shown to be an essential gene (Das, 1976; Bubunenko, 2007).<ref name='LIB:EcoGene'/>
rho has been shown to be an essential gene (Das, 1976; Bubunenko, 2007).<ref name='LIB:EcoGene'/>
* ''rho'' is required to maintain genomic integrity by resolving transcription/replication conflicts <ref name='PMID:21183718'/>
 
 
<noinclude>


==References==
==References==

Latest revision as of 21:55, 27 May 2013

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions
Standard Name

rho

Gene Synonym(s)

ECK3775, b3783, JW3756, nitA, nusD, psuA, rnsC, sun, tsu, psu, sbaA, suA[1], hdf, tabC

Product Desc.

transcription termination factor Rho; polarity suppressor[2][3];

Component of transcription termination factor Rho[3]

Transcription termination factor Rho; bicyclomycin target[4]

Product Synonyms(s)

transcription termination factor[1], B3783[2][1], RnsC[2][1], Tsu[2][1], Sun[2][1], NusD[2][1], Psu[2][1], SbaA[2][1], PsuA[2][1], NitA[2][1], Rho[2][1] , ECK3775, hdf, JW3756, nitA, nusD, psuA, rnsC, sbaA, sun, tabC, tsu, b3783

Function from GO

<GO_nr />

Knock-Out Phenotype
Regulation/Expression

transcription unit(s): rhoL[2], rhoL-rho[2], rho

Regulation/Activity
Quick Links



        

See Help:Quickview for help with entering information in the Quickview table.

Notes

[back to top]


  • The rho gene is often misannotated as a polarity suppressor. Mutations in rho suppress polarity.[5][6][7][8][9] Wild type rho is the source of polarity.
  • rho has been shown to be an essential gene (Das, 1976; Bubunenko, 2007).[4]
  • rho is required to maintain genomic integrity by resolving transcription/replication conflicts [10]

References

[back to top]


  1. ↑ 1.00 1.01 1.02 1.03 1.04 1.05 1.06 1.07 1.08 1.09 1.10 1.11 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.00 2.01 2.02 2.03 2.04 2.05 2.06 2.07 2.08 2.09 2.10 2.11 2.12 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  5. ↑ Das, A et al. (1976) Isolation and characterization of conditional lethal mutants of Escherichia coli defective in transcription termination factor rho. Proc. Natl. Acad. Sci. U.S.A. 73 1959-63 PubMed
  6. ↑ Korn, LJ & Yanofsky, C (1976) Polarity suppressors defective in transcription termination at the attenuator of the tryptophan operon of Escherichia coli have altered rho factor. J. Mol. Biol. 106 231-41 PubMed
  7. ↑ Belfort, M & Oppenheim, AB (1976) Efficient suppression of the requirement for N function of bacteriophage lambda by a Rho-defective E.coli suA mutant. Mol. Gen. Genet. 148 171-3 PubMed
  8. ↑ Richardson, JP & Carey, JL 3rd (1982) rho Factors from polarity suppressor mutants with defects in their RNA interactions. J. Biol. Chem. 257 5767-71 PubMed
  9. ↑ Das, A et al. (1978) Interaction of RNA polymerase and rho in transcription termination: coupled ATPase. Proc. Natl. Acad. Sci. U.S.A. 75 4828-32 PubMed
  10. ↑ Washburn, RS & Gottesman, ME (2011) Transcription termination maintains chromosome integrity. Proc. Natl. Acad. Sci. U.S.A. 108 792-7 PubMed