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!align=left {{table_heading_style}} |Standard Name
!align=left {{table_heading_style}} |Standard Name
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''putA''
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!align=left {{table_heading_style}} |Gene Synonym(s)
!align=left {{table_heading_style}} |Gene Synonym(s)
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''ECK1005, b1014, JW0999, poaA, putC, proline utilization A''<ref name='LIB:Riley_2006'/><ref name='LIB:EcoCyc10.6'/>
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!align=left {{table_heading_style}} |Product Desc.
!align=left {{table_heading_style}} |Product Desc.
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PutA bifunctional enzyme and transcriptional regulator<ref name='LIB:EcoCyc10.6'/>; PutA transcriptional repressor, Proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase<ref name='LIB:EcoCyc11.1'/>;
Component of [[:Category:Complex:PUTA-CPLX|PUTA-CPLX]]<ref name='LIB:EcoCyc10.6'/>; [[:Category:Complex:PUTA-CPLX|PutA transcriptional repressor, Proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase]]<ref name='LIB:EcoCyc11.1'/>
Proline dehydrogenase and repressor for the putAP divergon<ref name='LIB:EcoGene'/>
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!align=left {{table_heading_style}} |Product Synonyms(s)
!align=left {{table_heading_style}} |Product Synonyms(s)
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''fused DNA-binding transcriptional regulator<ref name='LIB:Riley_2006'/>, proline dehydrogenase<ref name='LIB:Riley_2006'/>, pyrroline-5-carboxylate dehydrogenase<ref name='LIB:Riley_2006'/>, B1014<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, PutC<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, PoaA<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, PutA<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/> , ECK1005, JW0999, poaA, putC, b1014''
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!align=left {{table_heading_style}} |Function from GO
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<GO_nr />
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!align=left {{table_heading_style}} |Knock-Out Phenotype
!align=left {{table_heading_style}} |Knock-Out Phenotype
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!align=left {{table_heading_style}} |Regulation/Expression
!align=left {{table_heading_style}} |Regulation/Expression
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transcription unit(s): [[:Category:Txn_unit:putA|putA]]<ref name='LIB:EcoCyc10.6'/>
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!align=left {{table_heading_style}} |Regulation/Activity
!align=left {{table_heading_style}} |Regulation/Activity
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!align=left {{table_heading_style}} |Quick Links
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[[File:porteco.png|link=http://porteco.org/AjaxSearch.jsp?searchString=putA&s=search]] [[File:EcoCyc.gif|link=http://biocyc.org/ECOLI/NEW-IMAGE?type=NIL&object=EG10801]] [[File:regulondb.jpg|link=http://regulondb.ccg.unam.mx/gene?term=ECK120000792&organism=ECK12&format=jsp&type=gene ]] <br/><br/> [[File:dnadisplay.png|link=http://ecoliwiki.net/tools/display_dna.php?gene=putA&loc=MG1655%3A1078105..1074143,W3110%3A1079304..1075342,DH10B%3A1132033..1128071,REL606%3A1095166..1091204,BW2952%3A977111..981073]] [[File:proteindisplay.png|link=http://ecoliwiki.net/tools/display_protein.php?f=NC_000913&start=977111&end=981073&gene=putA&aa=mgtttmgvklddatreriksaatridrtphwlikqaifsyleqlensdtlpelpallsgaanesdeaptpaeephqpfldfaeqilpqsvsraaitaayrrpeteavsmlleqarlpqpvaeqahklayqladklrnqknasgragmvqgllqefslssqegvalmclaeallripdkatrdalirdkisngnwqshigrspslfvnaatwgllftgklvsthneaslsrslnriigksgeplirkgvdmamrlmgeqfvtgetiaealanarkleekgfrysydmlgeaaltaadaqaymvsyqqaihaigkasngrgiyegpgisiklsalhprysraqydrvmeelyprlksltllarqydiginidaeesdrleisldlleklcfepelagwngigfviqayqkrcplvidylidlatrsrrrlmirlvkgaywdseikraqmdglegypvytrkvytdvsylacakkllavpnliypqfathnahtlaaiyqlagqnyypgqyefqclhgmgeplyeqvtgkvadgklnrpcriyapvgthetllaylvrrllengantsfvnriadtslpldelvadpvtaveklaqqegqtglphpkiplprdlyghgrdnsagldlanehrlaslssallnsalqkwqalpmleqpvaagemspvinpaepkdivgyvreatpreveqalesavnnapiwfatppaeraailhraavlmesqmqqligilvreagktfsnaiaevreavdflhyyagqvrddfanethrplgpvvcispwnfplaiftgqiaaalaagnsvlakpaeqtpliaaqgiailleagvppgvvqllpgrgetvgaqltgddrvrgvmftgstevatllqrniasrldaqgrpipliaetggmnamivdssalteqvvvdvlasafdsagqrcsalrvlclqdeiadhtlkmlrgamaecrmgnpgrlttdigpvidseakanierhiqtmrskgrpvfqavrensedarewqsgtfvaptlielddfaelqkevfgpvlhvvrynrnqlpelieqinasgygltlgvhtridetiaqvtgsahvgnlyvnrnmvgavvgvqpfggeglsgtgpkaggplylyrllanrpesalavtlarqdakypvdaqlkaaltqplnalrewaanrpelqalctqygelaqagtqrllpgptgerntwtllprervlciaddeqdaltqlaavlavgsqvlwpddalhrqlvkalpsavseriqlakaenitaqpfdavifhgdsdqlralceavaardgtivsvqgfargesnillerlyierslsvntaaaggnaslmtig]]&nbsp;&nbsp;  [[File:pubmed.jpg|link=http://www.ncbi.nlm.nih.gov/sites/entrez?db=pubmed&cmd=Search&Term=putA+AND+escherichia+coli]]&nbsp;&nbsp;  [[File:textpresso.jpg|link=http://textpresso.tamu.edu/cgi-bin/textpresso/search?q=putA]]&nbsp;&nbsp;


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Latest revision as of 21:54, 27 May 2013

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
References Suggestions
Standard Name

putA

Gene Synonym(s)

ECK1005, b1014, JW0999, poaA, putC, proline utilization A[1][2]

Product Desc.

PutA bifunctional enzyme and transcriptional regulator[2]; PutA transcriptional repressor, Proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase[3];

Component of PUTA-CPLX[2]; PutA transcriptional repressor, Proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase[3]

Proline dehydrogenase and repressor for the putAP divergon[4]

Product Synonyms(s)

fused DNA-binding transcriptional regulator[1], proline dehydrogenase[1], pyrroline-5-carboxylate dehydrogenase[1], B1014[2][1], PutC[2][1], PoaA[2][1], PutA[2][1] , ECK1005, JW0999, poaA, putC, b1014

Function from GO

<GO_nr />

Knock-Out Phenotype
Regulation/Expression

transcription unit(s): putA[2]

Regulation/Activity
Quick Links



        

See Help:Quickview for help with entering information in the Quickview table.

Notes

[back to top]


PutA is a multifunctional membrane-associated flavoprotein involved in proline catabolism: the central proline dehydrogenese domain feeds its product to the C-terminal Delta(1)-pyrroline-5-carboxylate dehydrogenese domain, to produce glutamate. The N-terminal 90 residue domain is the DNA-binding repressor domain. A divergon is a regulon comprised of two adjacent divergent operons or genes. Binds TrxA (Kumar, 2004).[4]



References

[back to top]


  1. ↑ 1.0 1.1 1.2 1.3 1.4 1.5 1.6 1.7 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 2.4 2.5 2.6 2.7 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.